E Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Probable intramembrane protease YKL100C
Description | Intramembrane aspartyl protease of the perinuclear ER membrane; acts in a branch of ER-associated degradation (ERAD) that degrades functional proteins rather than misfolded proteins; regulates abundance of high-affinity plasma membrane transporters, such as Ctr1p and Zrt1p, during the starvation response; has a presenilin fold; member of the GxGD family of intramembrane proteases; closest human homolog is signal peptide peptidase (SPP) [Source:SGD;Acc:S000001583]; transcript_id=YKL100C_mRNA |
Organism | YEAST - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Locus | [ Chromosome XI ]: 253697 ... 255460 |
Number of exons | 1 |
Exons | complement(253697..255460) |