E Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Pre-mRNA-splicing factor 8 [PRP8]
Description | Component of U4/U6-U5 snRNP complex; involved in second catalytic step of splicing; participates in spliceosomal assembly through its interaction with U1 snRNA; largest and most evolutionarily conserved protein of the spliceosome; mutations in human ortholog, PRPF8, cause Retinitis pigmentosa and missplicing in Myelodysplastic syndrome; mouse ortholog interacts with androgen receptor and may have a role in prostate cancer [Source:SGD;Acc:S000001208]; transcript_id=YHR165C_mRNA |
Organism | YEAST - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Locus | [ Chromosome VIII ]: 429707 ... 436948 |
Number of exons | 1 |
Exons | complement(429707..436948) |