Gene YEAST02950 (PRP8_YEAST)

E Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Pre-mRNA-splicing factor 8 [PRP8]

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General Information

DescriptionComponent of U4/U6-U5 snRNP complex; involved in second catalytic step of splicing; participates in spliceosomal assembly through its interaction with U1 snRNA; largest and most evolutionarily conserved protein of the spliceosome; mutations in human ortholog, PRPF8, cause Retinitis pigmentosa and missplicing in Myelodysplastic syndrome; mouse ortholog interacts with androgen receptor and may have a role in prostate cancer [Source:SGD;Acc:S000001208]; transcript_id=YHR165C_mRNA
Organism YEAST - Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Locus[ Chromosome VIII ]: 429707 ... 436948
Number of exons1
Exonscomplement(429707..436948)

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