E Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | E3 ubiquitin-protein ligase complex SLX5-SLX8 subu [SLX5]
Description | Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex; role in Ub-mediated degradation of histone variant Cse4p preventing mislocalization to euchromatin; role in proteolysis of spindle positioning protein Kar9p, and DNA repair proteins Rad52p and Rad57p; forms SUMO- dependent nuclear foci, including DNA repair centers; contains a RING domain and two SIM motifs; associates with the centromere; required for maintenance of genome integrity like human ortholog RNF4 [Source:SGD;Acc:S000002171]; transcript_id=YDL013W_mRNA |
Organism | YEAST - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Locus | [ Chromosome IV ]: 429067 ... 430926 |
Number of exons | 1 |
Exons | 429067..430926 |