E Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Degradation in the endoplasmic reticulum protein 1 [DER1]
Description | ER membrane protein that promotes export of misfolded polypeptides; required for ER-associated protein degradation of misfolded or unassembled proteins; initiates export of aberrant polypeptides from ER lumen by threading them into ER membrane and routing them to Hrd1p for ubiquitination; function normally requires N-terminal acetylation by NatB; N- and C- termini protrude into cytoplasm; similar to Dfm1p; homolog of mammalian derlin-1 [Source:SGD;Acc:S000000405]; transcript_id=YBR201W_mRNA |
Organism | YEAST - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Locus | [ Chromosome II ]: 623576 ... 624211 |
Number of exons | 1 |
Exons | 623576..624211 |