Entry MYCBO03714 (PKNF_MYCBO)

B Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)


General Information

Description
ANCHORED-MEMBRANE SERINE/THREONINE-PROTEIN KINASE PKNF (PROTEIN KINASE F) (STPK F) Mb1775, pknF, len: 476 aa. Equivalent to Rv1746, len: 476 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 476 aa overlap). pknF, transmembrane serine/threonine-protein kinase (EC 2.7.1.-) (see citations below), highly similar to KY28_MYCTU|Q10697 probable serine/threonine-protein kinase from Mycobacterium tuberculosis (589 aa), FASTA scores: opt: 870, E(): 0, (41.6% identity in 406 aa overlap). Contains PS00108 Serine/Threonine protein kinases active-site signature. Contains Hank's kinase subdomain. BELONGS TO THE SER/THR FAMILY OF PROTEIN KINASES. Experimental studies show evidence of auto-phosphorylation. Start site chosen by homology, may extend further upstream.
Organism
MYCBO - Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (Taxon-ID: 233413)
Locus
A43536..44966
Number of exons
1

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

Download: Fasta
MPLAEGSTFA GFTIVRQLGS GGMGEVYLAR HPRLPRQDAL KVLRADVSAD GEYRARFNRE    60
ADAAASLWHP HIVAVHDRGE FDGQLWIDMD FVDGTDTVSL LRDRYPNGMP GPEVTEIITA   120
VAEALDYAHE RRLLHRDVKP ANILIANPDS PDRRIMLADF GIAGWVDDPS GLTATNMTVG   180
TVSYAAPEQL MGNELDGRAD QYALAATAFH LLTGSPPFQH ANPAVVISQH LSASPPAIGD   240
RVPELTPLDP VFAKALAKQP KDRYQRCVDF ARALGHRLGG AGDPDDTRVS QPVAVAAPAK   300
RSLLRTAVIV PAVLAMLLVM AVAVTVREFQ RADDERAAQP ARTRTTTSAG TTTSVAPAST   360
TRPAPTTPTT TGAADTATAS PTAAVVAIGA LCFPLGSTGT TKTGATAYCS TLQGTNTTIW   420
SLTEDTVASP TVTATADPTE APLPIEQESP IRVCMQQTGQ TRRECREEIR RSNGWP       476

Coding Sequence

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ATGCCGCTCG CGGAAGGTTC GACGTTCGCC GGCTTCACCA TCGTCCGGCA GTTGGGATCC    60
GGCGGGATGG GCGAGGTGTA CCTGGCCCGG CATCCCAGAC TGCCCCGCCA GGACGCGCTC   120
AAGGTACTGC GGGCCGATGT GTCAGCCGAC GGCGAATACC GGGCACGGTT CAACCGCGAA   180
GCCGATGCCG CGGCGTCGCT GTGGCATCCA CACATCGTCG CCGTCCACGA CCGCGGCGAG   240
TTCGACGGCC AGCTCTGGAT CGACATGGAC TTCGTCGACG GCACCGACAC CGTATCCCTT   300
CTCAGGGATC GTTATCCGAA CGGGATGCCC GGCCCCGAGG TCACCGAGAT CATCACTGCG   360
GTGGCCGAAG CGCTCGACTA TGCCCACGAA CGTCGGCTGT TGCACCGCGA CGTCAAACCC   420
GCCAACATCC TGATCGCCAA TCCTGATTCA CCTGATCGTC GAATCATGTT GGCCGACTTC   480
GGGATCGCCG GCTGGGTCGA TGATCCAAGC GGATTGACCG CCACAAACAT GACTGTGGGC   540
ACCGTGTCAT ACGCGGCTCC GGAACAGCTT ATGGGCAACG AGCTCGATGG ACGGGCCGAC   600
CAATACGCAC TAGCCGCGAC GGCGTTTCAC TTGCTGACCG GCTCCCCGCC CTTTCAGCAC   660
GCCAACCCCG CCGTGGTGAT CAGCCAGCAT CTCAGCGCGT CACCCCCGGC GATCGGCGAT   720
CGGGTTCCCG AGCTGACACC GCTGGACCCG GTCTTCGCCA AAGCGCTGGC CAAGCAACCC   780
AAGGACCGTT ACCAGCGGTG TGTCGACTTC GCGCGCGCAC TCGGCCATCG TCTGGGCGGC   840
GCGGGTGATC CTGACGACAC GCGGGTGTCG CAACCGGTCG CCGTGGCCGC GCCCGCGAAA   900
CGCTCGCTGC TGCGGACCGC CGTCATCGTC CCCGCGGTGC TGGCGATGCT GCTGGTGATG   960
GCCGTCGCGG TCACCGTGCG GGAGTTCCAG CGTGCTGACG ACGAGCGTGC AGCGCAGCCT  1020
GCGCGGACGC GGACCACCAC ATCGGCCGGC ACGACCACTT CGGTAGCCCC CGCGAGCACA  1080
ACGCGCCCGG CCCCCACGAC CCCGACCACG ACTGGCGCCG CCGACACCGC GACTGCATCG  1140
CCGACCGCTG CGGTTGTCGC CATCGGCGCC CTCTGCTTCC CGCTCGGCAG CACCGGCACC  1200
ACCAAGACCG GGGCGACGGC CTACTGCTCG ACGCTGCAAG GCACCAACAC CACCATCTGG  1260
TCGCTGACCG AGGACACCGT GGCCAGTCCG ACTGTGACCG CCACTGCTGA CCCGACGGAG  1320
GCGCCGCTGC CCATCGAGCA GGAATCGCCG ATTCGAGTGT GCATGCAGCA GACCGGCCAG  1380
ACCCGACGGG AATGTCGCGA GGAGATTCGC AGAAGCAACG GCTGGCCGTG A           1431