Entry HUMAN27668 (WRN_HUMAN)

E Homo sapiens


General Information

Description
Werner syndrome RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:12791]
Organism
HUMAN - Homo sapiens (Taxon-ID: 9606)
Locus
8join(31058448..31058543, 31059153..31059265, 31064289..31064434, 31064915..31065063, 31067033..31067182, 31068258..31068327, 31076173..31076287, 31080867..31081296, 31083699..31083779, 31085166..31085246, 31087776..31087920, 31088890..31088965, 31090465..31090532, 31090834..31090942, 31091830..31091898, 31096768..31096850, 31100849..31100955, 31111615..31111799, 31116354..31116528, 31120243..31120424, 31124522..31124623, 31124908..31125000, 31132365..31132506, 31141430..31141600, 31141681..31141775, 31142626..31142701, 31143550..31143623, 31147053..31147128, 31147364..31147476, 31150341..31150455, 31154624..31154755, 31157368..31157530, 31167022..31167230, 31172995..31173102)
Number of exons
34

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

Download: Fasta
MSEKKLETTA QQRKCPEWMN VQNKRCAVEE RKACVRKSVF EDDLPFLEFT GSIVYSYDAS    60
DCSFLSEDIS MSLSDGDVVG FDMEWPPLYN RGKLGKVALI QLCVSESKCY LFHVSSMSVF   120
PQGLKMLLEN KAVKKAGVGI EGDQWKLLRD FDIKLKNFVE LTDVANKKLK CTETWSLNSL   180
VKHLLGKQLL KDKSIRCSNW SKFPLTEDQK LYAATDAYAG FIIYRNLEIL DDTVQRFAIN   240
KEEEILLSDM NKQLTSISEE VMDLAKHLPH AFSKLENPRR VSILLKDISE NLYSLRRMII   300
GSTNIETELR PSNNLNLLSF EDSTTGGVQQ KQIREHEVLI HVEDETWDPT LDHLAKHDGE   360
DVLGNKVERK EDGFEDGVED NKLKENMERA CLMSLDITEH ELQILEQQSQ EEYLSDIAYK   420
STEHLSPNDN ENDTSYVIES DEDLEMEMLK HLSPNDNEND TSYVIESDED LEMEMLKSLE   480
NLNSGTVEPT HSKCLKMERN LGLPTKEEEE DDENEANEGE EDDDKDFLWP APNEEQVTCL   540
KMYFGHSSFK PVQWKVIHSV LEERRDNVAV MATGYGKSLC FQYPPVYVGK IGLVISPLIS   600
LMEDQVLQLK MSNIPACFLG SAQSENVLTD IKLGKYRIVY VTPEYCSGNM GLLQQLEADI   660
GITLIAVDEA HCISEWGHDF RDSFRKLGSL KTALPMVPIV ALTATASSSI REDIVRCLNL   720
RNPQITCTGF DRPNLYLEVR RKTGNILQDL QPFLVKTSSH WEFEGPTIIY CPSRKMTQQV   780
TGELRKLNLS CGTYHAGMSF STRKDIHHRF VRDEIQCVIA TIAFGMGINK ADIRQVIHYG   840
APKDMESYYQ EIGRAGRDGL QSSCHVLWAP ADINLNRHLL TEIRNEKFRL YKLKMMAKME   900
KYLHSSRCRR QIILSHFEDK QVQKASLGIM GTEKCCDNCR SRLDHCYSMD DSEDTSWDFG   960
PQAFKLLSAV DILGEKFGIG LPILFLRGSN SQRLADQYRR HSLFGTGKDQ TESWWKAFSR  1020
QLITEGFLVE VSRYNKFMKI CALTKKGRNW LHKANTESQS LILQANEELC PKKLLLPSSK  1080
TVSSGTKEHC YNQVPVELST EKKSNLEKLY SYKPCDKISS GSNISKKSIM VQSPEKAYSS  1140
SQPVISAQEQ ETQIVLYGKL VEARQKHANK MDVPPAILAT NKILVDMAKM RPTTVENVKR  1200
IDGVSEGKAA MLAPLLEVIK HFCQTNSVQT DLFSSTKPQE EQKTSLVAKN KICTLSQSMA  1260
ITYSLFQEKK MPLKSIAESR ILPLMTIGMH LSQAVKAGCP LDLERAGLTP EVQKIIADVI  1320
RNPPVNSDMS KISLIRMLVP ENIDTYLIHM AIEILKHGPD SGLQPSCDVN KRRCFPGSEE  1380
ICSSSKRSKE EVGINTETSS AERKRRLPVW FAKGSDTSKK LMDKTKRGGL FS          1432

Coding Sequence

Download: Fasta
ATGAGTGAAA AAAAATTGGA AACAACTGCA CAGCAGCGGA AATGTCCTGA ATGGATGAAT    60
GTGCAGAATA AAAGATGTGC TGTAGAAGAA AGAAAGGCAT GTGTTCGGAA GAGTGTTTTT   120
GAAGATGACC TCCCCTTCTT AGAATTCACT GGATCCATTG TGTATAGTTA CGATGCTAGT   180
GATTGCTCTT TCCTGTCAGA AGATATTAGC ATGAGTCTAT CAGATGGGGA TGTGGTGGGA   240
TTTGACATGG AGTGGCCACC ATTATACAAT AGAGGGAAAC TTGGCAAAGT TGCACTAATT   300
CAGTTGTGTG TTTCTGAGAG CAAATGTTAC TTGTTCCACG TTTCTTCCAT GTCAGTTTTT   360
CCCCAGGGAT TAAAAATGTT GCTTGAAAAT AAAGCAGTTA AAAAGGCAGG TGTAGGAATT   420
GAAGGAGATC AGTGGAAACT TCTACGTGAC TTTGATATCA AATTGAAGAA TTTTGTGGAG   480
TTGACAGATG TTGCCAATAA AAAGCTGAAA TGCACAGAGA CCTGGAGCCT TAACAGTCTG   540
GTTAAACACC TCTTAGGTAA ACAGCTCCTG AAAGACAAGT CTATCCGCTG TAGCAATTGG   600
AGTAAATTTC CTCTCACTGA GGACCAGAAA CTGTATGCAG CCACTGATGC TTATGCTGGT   660
TTTATTATTT ACCGAAATTT AGAGATTTTG GATGATACTG TGCAAAGGTT TGCTATAAAT   720
AAAGAGGAAG AAATCCTACT TAGCGACATG AACAAACAGT TGACTTCAAT CTCTGAGGAA   780
GTGATGGATC TGGCTAAGCA TCTTCCTCAT GCTTTCAGTA AATTGGAAAA CCCACGGAGG   840
GTTTCTATCT TACTAAAGGA TATTTCAGAA AATCTATATT CACTGAGGAG GATGATAATT   900
GGGTCTACTA ACATTGAGAC TGAACTGAGG CCCAGCAATA ATTTAAACTT ATTATCCTTT   960
GAAGATTCAA CTACTGGGGG AGTACAACAG AAACAAATTA GAGAACATGA AGTTTTAATT  1020
CACGTTGAAG ATGAAACATG GGACCCAACA CTTGATCATT TAGCTAAACA TGATGGAGAA  1080
GATGTACTTG GAAATAAAGT GGAACGAAAA GAAGATGGAT TTGAAGATGG AGTAGAAGAC  1140
AACAAATTGA AAGAGAATAT GGAAAGAGCT TGTTTGATGT CGTTAGATAT TACAGAACAT  1200
GAACTCCAAA TTTTGGAACA GCAGTCTCAG GAAGAATATC TTAGTGATAT TGCTTATAAA  1260
TCTACTGAGC ATTTATCTCC CAATGATAAT GAAAACGATA CGTCCTATGT AATTGAGAGT  1320
GATGAAGATT TAGAAATGGA GATGCTTAAG CATTTATCTC CCAATGATAA TGAAAACGAT  1380
ACGTCCTATG TAATTGAGAG TGATGAAGAT TTAGAAATGG AGATGCTTAA GTCTTTAGAA  1440
AACCTCAATA GTGGCACGGT AGAACCAACT CATTCTAAAT GCTTAAAAAT GGAAAGAAAT  1500
CTGGGTCTTC CTACTAAAGA AGAAGAAGAA GATGATGAAA ATGAAGCTAA TGAAGGGGAA  1560
GAAGATGATG ATAAGGACTT TTTGTGGCCA GCACCCAATG AAGAGCAAGT TACTTGCCTC  1620
AAGATGTACT TTGGCCATTC CAGTTTTAAA CCAGTTCAGT GGAAAGTGAT TCATTCAGTA  1680
TTAGAAGAAA GAAGAGATAA TGTTGCTGTC ATGGCAACTG GATATGGAAA GAGTTTGTGC  1740
TTCCAGTATC CACCTGTTTA TGTAGGCAAG ATTGGCCTTG TTATCTCTCC CCTTATTTCT  1800
CTGATGGAAG ACCAAGTGCT ACAGCTTAAA ATGTCCAACA TCCCAGCTTG CTTCCTTGGA  1860
TCAGCACAGT CAGAAAATGT TCTAACAGAT ATTAAATTAG GTAAATACCG GATTGTATAC  1920
GTAACTCCAG AATACTGTTC AGGTAACATG GGCCTGCTCC AGCAACTTGA GGCTGATATT  1980
GGTATCACGC TCATTGCTGT GGATGAGGCT CACTGTATTT CTGAGTGGGG GCATGATTTT  2040
AGGGATTCAT TCAGGAAGTT GGGCTCCCTA AAGACAGCAC TGCCAATGGT TCCAATCGTT  2100
GCACTTACTG CTACTGCAAG TTCTTCAATC CGGGAAGACA TTGTACGTTG CTTAAATCTG  2160
AGAAATCCTC AGATCACCTG TACTGGTTTT GATCGACCAA ACCTGTATTT AGAAGTTAGG  2220
CGAAAAACAG GGAATATCCT TCAGGATCTG CAGCCATTTC TTGTCAAAAC AAGTTCCCAC  2280
TGGGAATTTG AAGGTCCAAC AATCATCTAC TGTCCTTCTA GAAAAATGAC ACAACAAGTT  2340
ACAGGTGAAC TTAGGAAACT GAATCTATCC TGTGGAACAT ACCATGCGGG CATGAGTTTT  2400
AGCACAAGGA AAGACATTCA TCATAGGTTT GTAAGAGATG AAATTCAGTG TGTCATAGCT  2460
ACCATAGCTT TTGGAATGGG CATTAATAAA GCTGACATTC GCCAAGTCAT TCATTACGGT  2520
GCTCCTAAGG ACATGGAATC ATATTATCAG GAGATTGGTA GAGCTGGTCG TGATGGACTT  2580
CAAAGTTCTT GTCACGTCCT CTGGGCTCCT GCAGACATTA ACTTAAATAG GCACCTTCTT  2640
ACTGAGATAC GTAATGAGAA GTTTCGATTA TACAAATTAA AGATGATGGC AAAGATGGAA  2700
AAATATCTTC ATTCTAGCAG ATGTAGGAGA CAAATCATCT TGTCTCATTT TGAGGACAAA  2760
CAAGTACAAA AAGCCTCCTT GGGAATTATG GGAACTGAAA AATGCTGTGA TAATTGCAGG  2820
TCCAGATTGG ATCATTGCTA TTCCATGGAT GACTCAGAGG ATACATCCTG GGACTTTGGT  2880
CCACAAGCAT TTAAGCTTTT GTCTGCTGTG GACATCTTAG GCGAAAAATT TGGAATTGGG  2940
CTTCCAATTT TATTTCTCCG AGGATCTAAT TCTCAGCGTC TTGCCGATCA ATATCGCAGG  3000
CACAGTTTAT TTGGCACTGG CAAGGATCAA ACAGAGAGTT GGTGGAAGGC TTTTTCCCGT  3060
CAGCTGATCA CTGAGGGATT CTTGGTAGAA GTTTCTCGGT ATAACAAATT TATGAAGATT  3120
TGCGCCCTTA CGAAAAAGGG TAGAAATTGG CTTCATAAAG CTAATACAGA ATCTCAGAGC  3180
CTCATCCTTC AAGCTAATGA AGAATTGTGT CCAAAGAAGT TGCTTCTGCC TAGTTCGAAA  3240
ACTGTATCTT CGGGCACCAA AGAGCATTGT TATAATCAAG TACCAGTTGA ATTAAGTACA  3300
GAGAAGAAGT CTAACTTGGA GAAGTTATAT TCTTATAAAC CATGTGATAA GATTTCTTCT  3360
GGGAGTAACA TTTCTAAAAA AAGTATCATG GTACAGTCAC CAGAAAAAGC TTACAGTTCC  3420
TCACAGCCTG TTATTTCGGC ACAAGAGCAG GAGACTCAGA TTGTGTTATA TGGCAAATTG  3480
GTAGAAGCTA GGCAGAAACA TGCCAATAAA ATGGATGTTC CCCCAGCTAT TCTGGCAACA  3540
AACAAGATAC TGGTGGATAT GGCCAAAATG AGACCAACTA CGGTTGAAAA CGTAAAAAGG  3600
ATTGATGGTG TTTCTGAAGG CAAAGCTGCC ATGTTGGCCC CTCTGTTGGA AGTCATCAAA  3660
CATTTCTGCC AAACAAATAG TGTTCAGACA GACCTCTTTT CAAGTACAAA ACCTCAAGAA  3720
GAACAGAAGA CGAGTCTGGT AGCAAAAAAT AAAATATGCA CACTTTCACA GTCTATGGCC  3780
ATCACATACT CTTTATTCCA AGAAAAGAAG ATGCCTTTGA AGAGCATAGC TGAGAGCAGG  3840
ATTCTGCCTC TCATGACAAT TGGCATGCAC TTATCCCAAG CGGTGAAAGC TGGCTGCCCC  3900
CTTGATTTGG AGCGAGCAGG CCTGACTCCA GAGGTTCAGA AGATTATTGC TGATGTTATC  3960
CGAAACCCTC CCGTCAACTC AGATATGAGT AAAATTAGCC TAATCAGAAT GTTAGTTCCT  4020
GAAAACATTG ACACGTACCT TATCCACATG GCAATTGAGA TCCTTAAACA TGGTCCTGAC  4080
AGCGGACTTC AACCTTCATG TGATGTCAAC AAAAGGAGAT GTTTTCCCGG TTCTGAAGAG  4140
ATCTGTTCAA GTTCTAAGAG AAGCAAGGAA GAAGTAGGCA TCAATACTGA GACTTCATCT  4200
GCAGAGAGAA AGAGACGATT ACCTGTGTGG TTTGCCAAAG GAAGTGATAC CAGCAAGAAA  4260
TTAATGGACA AAACGAAAAG GGGAGGTCTT TTTAGTTAA                         4299