Entry HUMAN25699 (GRM1_HUMAN)

E Homo sapiens


General Information

Description
glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593]
Organism
HUMAN - Homo sapiens (Taxon-ID: 9606)
Locus
6join(146029518..146030217, 146159348..146159597, 146304611..146304846, 146352250..146352496, 146357526..146357694, 146386890..146387016, 146398769..146399699, 146433872..146434796)
Number of exons
8

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

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MVGLLLFFFP AIFLEVSLLP RSPGRKVLLA GASSQRSVAR MDGDVIIGAL FSVHHQPPAE    60
KVPERKCGEI REQYGIQRVE AMFHTLDKIN ADPVLLPNIT LGSEIRDSCW HSSVALEQSI   120
EFIRDSLISI RDEKDGINRC LPDGQSLPPG RTKKPIAGVI GPGSSSVAIQ VQNLLQLFDI   180
PQIAYSATSI DLSDKTLYKY FLRVVPSDTL QARAMLDIVK RYNWTYVSAV HTEGNYGESG   240
MDAFKELAAQ EGLCIAHSDK IYSNAGEKSF DRLLRKLRER LPKARVVVCF CEGMTVRGLL   300
SAMRRLGVVG EFSLIGSDGW ADRDEVIEGY EVEANGGITI KLQSPEVRSF DDYFLKLRLD   360
TNTRNPWFPE FWQHRFQCRL PGHLLENPNF KRICTGNESL EENYVQDSKM GFVINAIYAM   420
AHGLQNMHHA LCPGHVGLCD AMKPIDGSKL LDFLIKSSFI GVSGEEVWFD EKGDAPGRYD   480
IMNLQYTEAN RYDYVHVGTW HEGVLNIDDY KIQMNKSGVV RSVCSEPCLK GQIKVIRKGE   540
VSCCWICTAC KENEYVQDEF TCKACDLGWW PNADLTGCEP IPVRYLEWSN IESIIAIAFS   600
CLGILVTLFV TLIFVLYRDT PVVKSSSREL CYIILAGIFL GYVCPFTLIA KPTTTSCYLQ   660
RLLVGLSSAM CYSALVTKTN RIARILAGSK KKICTRKPRF MSAWAQVIIA SILISVQLTL   720
VVTLIIMEPP MPILSYPSIK EVYLICNTSN LGVVAPLGYN GLLIMSCTYY AFKTRNVPAN   780
FNEAKYIAFT MYTTCIIWLA FVPIYFGSNY KIITTCFAVS LSVTVALGCM FTPKMYIIIA   840
KPERNVRSAF TTSDVVRMHV GDGKLPCRSN TFLNIFRRKK AGAGNANSNG KSVSWSEPGG   900
GQVPKGQHMW HRLSVHVKTN ETACNQTAVI KPLTKSYQGS GKSLTFSDTS TKTLYNVEEE   960
EDAQPIRFSP PGSPSMVVHR RVPSAATTPP LPSHLTAEET PLFLAEPALP KGLPPPLQQQ  1020
QQPPPQQKSL MDQLQGVVSN FSTAIPDFHA VLAGPGGPGN GLRSLYPPPP PPQHLQMLPL  1080
QLSTFGEELV SPPADDDDDS ERFKLLQEYV YEHEREGNTE EDELEEEEED LQAASKLTPD  1140
DSPALTPPSP FRDSVASGSS VPSSPVSESV LCTPPNVSYA SVILRDYKQS SSTL        1194

Coding Sequence

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ATGGTCGGGC TCCTTTTGTT TTTTTTCCCA GCGATCTTTT TGGAGGTGTC CCTTCTCCCC    60
AGAAGCCCCG GCAGGAAAGT GTTGCTGGCA GGAGCGTCGT CTCAGCGCTC GGTGGCCAGA   120
ATGGACGGAG ATGTCATCAT TGGAGCCCTC TTCTCAGTCC ATCACCAGCC TCCGGCCGAG   180
AAAGTGCCCG AGAGGAAGTG TGGGGAGATC AGGGAGCAGT ATGGCATCCA GAGGGTGGAG   240
GCCATGTTCC ACACGTTGGA TAAGATCAAC GCGGACCCGG TCCTCCTGCC CAACATCACC   300
CTGGGCAGTG AGATCCGGGA CTCCTGCTGG CACTCTTCCG TGGCTCTGGA ACAGAGCATT   360
GAGTTCATTA GGGACTCTCT GATTTCCATT CGAGATGAGA AGGATGGGAT CAACCGGTGT   420
CTGCCTGACG GCCAGTCCCT CCCCCCAGGC AGGACTAAGA AGCCCATTGC GGGAGTGATC   480
GGTCCCGGCT CCAGCTCTGT AGCCATTCAA GTGCAGAACC TGCTCCAGCT CTTCGACATC   540
CCCCAGATCG CTTATTCAGC CACAAGCATC GACCTGAGTG ACAAAACTTT GTACAAATAC   600
TTCCTGAGGG TTGTCCCTTC TGACACTTTG CAGGCAAGGG CCATGCTTGA CATAGTCAAA   660
CGTTACAATT GGACCTATGT CTCTGCAGTC CACACGGAAG GGAATTATGG GGAGAGCGGA   720
ATGGACGCTT TCAAAGAGCT GGCTGCCCAG GAAGGCCTCT GTATCGCCCA TTCTGACAAA   780
ATCTACAGCA ACGCTGGGGA GAAGAGCTTT GACCGACTCT TGCGCAAACT CCGAGAGAGG   840
CTTCCCAAGG CTAGAGTGGT GGTCTGCTTC TGTGAAGGCA TGACAGTGCG AGGACTCCTG   900
AGCGCCATGC GGCGCCTTGG CGTCGTGGGC GAGTTCTCAC TCATTGGAAG TGATGGATGG   960
GCAGACAGAG ATGAAGTCAT TGAAGGTTAT GAGGTGGAAG CCAACGGGGG AATCACGATA  1020
AAGCTGCAGT CTCCAGAGGT CAGGTCATTT GATGATTATT TCCTGAAACT GAGGCTGGAC  1080
ACTAACACGA GGAATCCCTG GTTCCCTGAG TTCTGGCAAC ATCGGTTCCA GTGCCGCCTT  1140
CCAGGACACC TTCTGGAAAA TCCCAACTTT AAACGAATCT GCACAGGCAA TGAAAGCTTA  1200
GAAGAAAACT ATGTCCAGGA CAGTAAGATG GGGTTTGTCA TCAATGCCAT CTATGCCATG  1260
GCACATGGGC TGCAGAACAT GCACCATGCC CTCTGCCCTG GCCACGTGGG CCTCTGCGAT  1320
GCCATGAAGC CCATCGACGG CAGCAAGCTG CTGGACTTCC TCATCAAGTC CTCATTCATT  1380
GGAGTATCTG GAGAGGAGGT GTGGTTTGAT GAGAAAGGAG ACGCTCCTGG AAGGTATGAT  1440
ATCATGAATC TGCAGTACAC TGAAGCTAAT CGCTATGACT ATGTGCACGT TGGAACCTGG  1500
CATGAAGGAG TGCTGAACAT TGATGATTAC AAAATCCAGA TGAACAAGAG TGGAGTGGTG  1560
CGGTCTGTGT GCAGTGAGCC TTGCTTAAAG GGCCAGATTA AGGTTATACG GAAAGGAGAA  1620
GTGAGCTGCT GCTGGATTTG CACGGCCTGC AAAGAGAATG AATATGTGCA AGATGAGTTC  1680
ACCTGCAAAG CTTGTGACTT GGGATGGTGG CCCAATGCAG ATCTAACAGG CTGTGAGCCC  1740
ATTCCTGTGC GCTATCTTGA GTGGAGCAAC ATCGAATCCA TTATAGCCAT CGCCTTTTCA  1800
TGCCTGGGAA TCCTTGTTAC CTTGTTTGTC ACCCTAATCT TTGTACTGTA CCGGGACACA  1860
CCAGTGGTCA AATCCTCCAG TCGGGAGCTC TGCTACATCA TCCTAGCTGG CATCTTCCTT  1920
GGTTATGTGT GCCCATTCAC TCTCATTGCC AAACCTACTA CCACCTCCTG CTACCTCCAG  1980
CGCCTCTTGG TTGGCCTCTC CTCTGCGATG TGCTACTCTG CTTTAGTGAC TAAAACCAAT  2040
CGTATTGCAC GCATCCTGGC TGGCAGCAAG AAGAAGATCT GCACCCGGAA GCCCAGGTTC  2100
ATGAGTGCCT GGGCTCAGGT GATCATTGCC TCAATTCTGA TTAGTGTGCA ACTAACCCTG  2160
GTGGTAACCC TGATCATCAT GGAACCCCCT ATGCCCATTC TGTCCTACCC AAGTATCAAG  2220
GAAGTCTACC TTATCTGCAA TACCAGCAAC CTGGGTGTGG TGGCCCCTTT GGGCTACAAT  2280
GGACTCCTCA TCATGAGCTG TACCTACTAT GCCTTCAAGA CCCGCAACGT GCCCGCCAAC  2340
TTCAACGAGG CCAAATATAT CGCGTTCACC ATGTACACCA CCTGTATCAT CTGGCTAGCT  2400
TTTGTGCCCA TTTACTTTGG GAGCAACTAC AAGATCATCA CAACTTGCTT TGCAGTGAGT  2460
CTCAGTGTAA CAGTGGCTCT GGGGTGCATG TTCACTCCCA AGATGTACAT CATTATTGCC  2520
AAGCCTGAGA GGAATGTCCG CAGTGCCTTC ACCACCTCTG ATGTTGTCCG CATGCATGTT  2580
GGCGATGGCA AGCTGCCCTG CCGCTCCAAC ACTTTCCTCA ACATCTTCCG AAGAAAGAAG  2640
GCAGGGGCAG GGAATGCCAA TTCTAATGGC AAGTCTGTGT CATGGTCTGA ACCAGGTGGA  2700
GGACAGGTGC CCAAGGGACA GCATATGTGG CACCGCCTCT CTGTGCACGT GAAGACCAAT  2760
GAGACGGCCT GCAACCAAAC AGCCGTCATC AAGCCCCTCA CTAAAAGTTA CCAAGGCTCT  2820
GGCAAGAGCC TGACCTTTTC AGATACCAGC ACCAAGACCC TTTACAACGT AGAGGAGGAG  2880
GAGGATGCCC AGCCGATTCG CTTTAGCCCG CCTGGTAGCC CTTCCATGGT GGTGCACAGG  2940
CGCGTGCCAA GCGCGGCGAC CACTCCGCCT CTGCCGTCCC ACCTGACCGC AGAGGAGACC  3000
CCCCTCTTCC TGGCCGAACC AGCCCTCCCC AAGGGCTTGC CCCCTCCTCT CCAGCAGCAG  3060
CAGCAACCCC CTCCACAGCA GAAATCGCTG ATGGACCAGC TCCAGGGAGT GGTCAGCAAC  3120
TTCAGTACCG CGATCCCGGA TTTTCACGCG GTGCTGGCAG GCCCCGGTGG TCCCGGGAAC  3180
GGGCTGCGGT CCCTGTACCC GCCCCCGCCA CCTCCGCAGC ACCTGCAGAT GCTGCCGCTG  3240
CAGCTGAGCA CCTTTGGGGA GGAGCTGGTC TCCCCGCCCG CGGACGACGA CGACGACAGC  3300
GAGAGGTTTA AGCTCCTCCA GGAGTACGTG TATGAGCACG AGCGGGAAGG GAACACGGAA  3360
GAAGACGAAC TGGAAGAGGA GGAGGAGGAC CTGCAGGCGG CCAGCAAACT GACCCCGGAT  3420
GATTCGCCTG CGCTGACGCC TCCGTCGCCT TTCCGCGACT CGGTGGCCTC GGGCAGCTCG  3480
GTGCCCAGCT CCCCCGTGTC CGAGTCGGTG CTCTGCACCC CTCCCAACGT ATCCTACGCC  3540
TCTGTCATTC TGCGGGACTA CAAGCAAAGC TCTTCCACCC TGTAA                  3585