Entry HUMAN22857 (PLK4_HUMAN)

E Homo sapiens


General Information

Description
polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397]
Organism
HUMAN - Homo sapiens (Taxon-ID: 9606)
Locus
4join(127881135..127881164, 127881831..127881926, 127883262..127883357, 127883439..127883553, 127885708..127886728, 127887396..127887496, 127889866..127890236, 127891092..127891196, 127891579..127891681, 127892365..127892514, 127893285..127893418, 127893513..127893604, 127893734..127893881, 127894953..127895093, 127896801..127896907, 127898439..127898541)
Number of exons
16

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

Download: Fasta
MATCIGEKIE DFKVGNLLGK GSFAGVYRAE SIHTGLEVAI KMIDKKAMYK AGMVQRVQNE    60
VKIHCQLKHP SILELYNYFE DSNYVYLVLE MCHNGEMNRY LKNRVKPFSE NEARHFMHQI   120
ITGMLYLHSH GILHRDLTLS NLLLTRNMNI KIADFGLATQ LKMPHEKHYT LCGTPNYISP   180
EIATRSAHGL ESDVWSLGCM FYTLLIGRPP FDTDTVKNTL NKVVLADYEM PSFLSIEAKD   240
LIHQLLRRNP ADRLSLSSVL DHPFMSRNSS TKSKDLGTVE DSIDSGHATI STAITASSST   300
SISGSLFDKR RLLIGQPLPN KMTVFPKNKS STDFSSSGDG NSFYTQWGNQ ETSNSGRGRV   360
IQDAEERPHS RYLRRAYSSD RSGTSNSQSQ AKTYTMERCH SAEMLSVSKR SGGGENEERY   420
SPTDNNANIF NFFKEKTSSS SGSFERPDNN QALSNHLCPG KTPFPFADPT PQTETVQQWF   480
GNLQINAHLR KTTEYDSISP NRDFQGHPDL QKDTSKNAWT DTKVKKNSDA SDNAHSVKQQ   540
NTMKYMTALH SKPEIIQQEC VFGSDPLSEQ SKTRGMEPPW GYQNRTLRSI TSPLVAHRLK   600
PIRQKTKKAV VSILDSEEVC VELVKEYASQ EYVKEVLQIS SDGNTITIYY PNGGRGFPLA   660
DRPPSPTDNI SRYSFDNLPE KYWRKYQYAS RFVQLVRSKS PKITYFTRYA KCILMENSPG   720
ADFEVWFYDG VKIHKTEDFI QVIEKTGKSY TLKSESEVNS LKEEIKMYMD HANEGHRICL   780
ALESIISEEE RKTRSAPFFP IIIGRKPGST SSPKALSPPP SVDSNYPTRE RASFNRMVMH   840
SAASPTQAPI LNPSMVTNEG LGLTTTASGT DISSNSLKDC LPKSAQLLKS VFVKNVGWAT   900
QLTSGAVWVQ FNDGSQLVVQ AGVSSISYTS PNGQTTRYGE NEKLPDYIKQ KLQCLSSILL   960
MFSNPTPNFH                                                          970

Coding Sequence

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ATGGCGACCT GCATCGGGGA GAAGATCGAG GATTTTAAAG TTGGAAATCT GCTTGGTAAA    60
GGATCATTTG CTGGTGTCTA CAGAGCTGAG TCCATTCACA CTGGTTTGGA AGTTGCAATC   120
AAAATGATAG ATAAGAAAGC CATGTACAAA GCAGGAATGG TACAGAGAGT CCAAAATGAG   180
GTGAAAATAC ATTGCCAATT GAAACATCCT TCTATCTTGG AGCTTTATAA CTATTTTGAA   240
GATAGCAATT ATGTGTATCT GGTATTAGAA ATGTGCCATA ATGGAGAAAT GAACAGGTAT   300
CTAAAGAATA GAGTGAAACC CTTCTCAGAA AATGAAGCTC GACACTTCAT GCACCAGATC   360
ATCACAGGGA TGTTGTATCT TCATTCTCAT GGTATACTAC ACCGGGACCT CACACTTTCT   420
AACCTCCTAC TGACTCGTAA TATGAACATC AAGATTGCTG ATTTTGGGCT GGCAACTCAA   480
CTGAAAATGC CACATGAAAA GCACTATACA TTATGTGGAA CTCCTAACTA CATTTCACCA   540
GAAATTGCCA CTCGAAGTGC ACATGGCCTT GAATCTGATG TTTGGTCCCT GGGCTGTATG   600
TTTTATACAT TACTTATCGG GAGACCACCC TTCGACACTG ACACAGTCAA GAACACATTA   660
AATAAAGTAG TATTGGCAGA TTATGAAATG CCATCTTTTT TGTCAATAGA GGCCAAGGAC   720
CTTATTCACC AGTTACTTCG TAGAAATCCA GCAGATCGTT TAAGTCTGTC TTCAGTATTG   780
GACCATCCTT TTATGTCCCG AAATTCTTCA ACAAAAAGTA AAGATTTAGG AACTGTGGAA   840
GACTCAATTG ATAGTGGGCA TGCCACAATT TCTACTGCAA TTACAGCTTC TTCCAGTACC   900
AGTATAAGTG GTAGTTTATT TGACAAAAGA AGACTTTTGA TTGGTCAGCC ACTCCCAAAT   960
AAAATGACTG TATTTCCAAA GAATAAAAGT TCAACTGATT TTTCTTCTTC AGGAGATGGA  1020
AACAGTTTTT ATACTCAGTG GGGAAATCAA GAAACCAGTA ATAGTGGAAG GGGAAGAGTA  1080
ATTCAAGATG CAGAAGAAAG GCCACATTCT CGATACCTTC GTAGAGCTTA TTCCTCTGAT  1140
AGATCTGGCA CTTCTAATAG TCAGTCTCAA GCAAAAACAT ATACAATGGA ACGATGTCAC  1200
TCAGCAGAAA TGCTTTCAGT GTCCAAAAGA TCAGGAGGAG GTGAAAATGA AGAGAGGTAC  1260
TCACCCACAG ACAACAATGC CAACATTTTT AACTTCTTTA AAGAAAAGAC ATCCAGTAGT  1320
TCTGGATCTT TTGAAAGACC TGATAACAAT CAAGCACTCT CCAATCATCT TTGTCCAGGA  1380
AAAACTCCTT TTCCATTTGC AGACCCGACA CCTCAGACTG AAACCGTACA ACAGTGGTTT  1440
GGGAATCTGC AAATAAATGC TCATTTAAGA AAAACTACTG AATATGACAG CATCAGCCCA  1500
AACCGGGACT TCCAGGGCCA TCCAGATTTG CAGAAGGACA CATCAAAAAA TGCCTGGACT  1560
GATACAAAAG TCAAAAAGAA CTCTGATGCT TCTGATAATG CACATTCTGT AAAACAGCAA  1620
AATACCATGA AATATATGAC TGCACTTCAC AGTAAACCTG AGATAATCCA ACAAGAATGT  1680
GTTTTTGGCT CAGATCCTCT TTCTGAACAG AGCAAGACTA GGGGTATGGA GCCACCATGG  1740
GGTTATCAGA ATCGTACATT AAGAAGCATT ACATCTCCGT TGGTTGCTCA CAGGTTAAAA  1800
CCAATCAGAC AGAAAACCAA AAAGGCTGTG GTGAGCATAC TTGATTCAGA GGAGGTGTGT  1860
GTGGAGCTTG TAAAGGAGTA TGCATCTCAA GAATATGTGA AAGAAGTTCT TCAGATATCT  1920
AGTGATGGAA ATACGATCAC TATTTATTAT CCAAATGGTG GTAGAGGTTT TCCTCTTGCT  1980
GATAGACCAC CCTCACCTAC TGACAACATC AGTAGGTACA GCTTTGACAA TTTACCAGAA  2040
AAATACTGGC GAAAATATCA ATATGCTTCC AGGTTTGTAC AGCTTGTAAG ATCTAAATCT  2100
CCCAAAATCA CTTATTTTAC AAGATATGCT AAATGCATTT TGATGGAGAA TTCTCCTGGT  2160
GCTGATTTTG AGGTTTGGTT TTATGATGGG GTAAAAATAC ACAAAACAGA AGATTTCATT  2220
CAGGTGATTG AAAAGACAGG GAAGTCTTAC ACTTTAAAAA GTGAAAGTGA AGTTAATAGC  2280
TTGAAAGAGG AGATAAAAAT GTATATGGAC CATGCTAATG AGGGTCATCG TATTTGTTTA  2340
GCACTGGAAT CCATAATTTC AGAAGAGGAA AGGAAAACTA GGAGTGCTCC CTTTTTCCCA  2400
ATAATCATAG GAAGAAAACC TGGTAGTACT AGTTCACCTA AGGCCTTATC ACCTCCTCCT  2460
TCTGTGGATT CAAATTACCC AACGAGAGAG AGAGCATCTT TCAACAGAAT GGTCATGCAT  2520
AGTGCTGCTT CTCCAACACA GGCACCAATC CTTAATCCCT CTATGGTTAC AAATGAAGGA  2580
CTTGGTCTTA CAACTACAGC TTCTGGAACA GACATCTCTT CTAATAGTCT AAAAGATTGT  2640
CTTCCTAAAT CAGCACAACT TTTGAAATCT GTTTTTGTGA AAAATGTTGG TTGGGCTACA  2700
CAGTTAACTA GTGGAGCTGT GTGGGTTCAG TTTAATGATG GGTCCCAGTT GGTTGTGCAG  2760
GCAGGAGTGT CTTCTATCAG TTATACCTCA CCAAATGGTC AAACAACTAG GTATGGAGAA  2820
AATGAAAAAT TACCAGACTA CATCAAACAG AAATTACAGT GTCTGTCTTC CATCCTTTTG  2880
ATGTTTTCTA ATCCGACTCC TAATTTTCAT TGA                               2913