Entry HUMAN20602 (TOP2B_HUMAN)

E Homo sapiens


General Information

Description
topoisomerase (DNA) II beta [Source:HGNC Symbol;Acc:HGNC:11990]
Organism
HUMAN - Homo sapiens (Taxon-ID: 9606)
Locus
3join(complement(25664229..25664297), complement(25645300..25645470), complement(25643694..25643784), complement(25642322..25642385), complement(25638165..25638310), complement(25637215..25637312), complement(25635936..25636148), complement(25633841..25634014), complement(25632693..25632794), complement(25632446..25632583), complement(25630801..25630939), complement(25630312..25630469), complement(25630029..25630154), complement(25629035..25629145), complement(25628847..25628952), complement(25627187..25627296), complement(25626772..25626864), complement(25626560..25626674), complement(25624682..25624803), complement(25624297..25624445), complement(25623515..25623746), complement(25620682..25620816), complement(25619862..25620062), complement(25618654..25618849), complement(25618418..25618509), complement(25615431..25615586), complement(25615205..25615288), complement(25612515..25612709), complement(25609568..25609712), complement(25609183..25609344), complement(25607171..25607375), complement(25606043..25606122), complement(25604760..25604870), complement(25601100..25601225), complement(25599435..25599529), complement(25598307..25598477))
Number of exons
36

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

Download: Fasta
MAKSGGCGAG AGVGGGNGAL TWVTLFDQNN AAKKEESETA NKNDSSKKLS VERVYQKKTQ    60
LEHILLRPDT YIGSVEPLTQ FMWVYDEDVG MNCREVTFVP GLYKIFDEIL VNAADNKQRD   120
KNMTCIKVSI DPESNIISIW NNGKGIPVVE HKVEKVYVPA LIFGQLLTSS NYDDDEKKVT   180
GGRNGYGAKL CNIFSTKFTV ETACKEYKHS FKQTWMNNMM KTSEAKIKHF DGEDYTCITF   240
QPDLSKFKME KLDKDIVALM TRRAYDLAGS CRGVKVMFNG KKLPVNGFRS YVDLYVKDKL   300
DETGVALKVI HELANERWDV CLTLSEKGFQ QISFVNSIAT TKGGRHVDYV VDQVVGKLIE   360
VVKKKNKAGV SVKPFQVKNH IWVFINCLIE NPTFDSQTKE NMTLQPKSFG SKCQLSEKFF   420
KAASNCGIVE SILNWVKFKA QTQLNKKCSS VKYSKIKGIP KLDDANDAGG KHSLECTLIL   480
TEGDSAKSLA VSGLGVIGRD RYGVFPLRGK ILNVREASHK QIMENAEINN IIKIVGLQYK   540
KSYDDAESLK TLRYGKIMIM TDQDQDGSHI KGLLINFIHH NWPSLLKHGF LEEFITPIVK   600
ASKNKQELSF YSIPEFDEWK KHIENQKAWK IKYYKGLGTS TAKEAKEYFA DMERHRILFR   660
YAGPEDDAAI TLAFSKKKID DRKEWLTNFM EDRRQRRLHG LPEQFLYGTA TKHLTYNDFI   720
NKELILFSNS DNERSIPSLV DGFKPGQRKV LFTCFKRNDK REVKVAQLAG SVAEMSAYHH   780
GEQALMMTIV NLAQNFVGSN NINLLQPIGQ FGTRLHGGKD AASPRYIFTM LSTLARLLFP   840
AVDDNLLKFL YDDNQRVEPE WYIPIIPMVL INGAEGIGTG WACKLPNYDA REIVNNVRRM   900
LDGLDPHPML PNYKNFKGTI QELGQNQYAV SGEIFVVDRN TVEITELPVR TWTQVYKEQV   960
LEPMLNGTDK TPALISDYKE YHTDTTVKFV VKMTEEKLAQ AEAAGLHKVF KLQTTLTCNS  1020
MVLFDHMGCL KKYETVQDIL KEFFDLRLSY YGLRKEWLVG MLGAESTKLN NQARFILEKI  1080
QGKITIENRS KKDLIQMLVQ RGYESDPVKA WKEAQEKAAE EDETQNQHDD SSSDSGTPSG  1140
PDFNYILNMS LWSLTKEKVE ELIKQRDAKG REVNDLKRKS PSDLWKEDLA AFVEELDKVE  1200
SQEREDVLAG MSGKAIKGKV GKPKVKKLQL EETMPSPYGR RIIPEITAMK ADASKKLLKK  1260
KKGDLDTAAV KVEFDEEFSG APVEGAGEEA LTPSVPINKG PKPKREKKEP GTRVRKTPTS  1320
SGKPSAKKVK KRNPWSDDES KSESDLEETE PVVIPRDSLL RRAAAERPKY TFDFSEEEDD  1380
DADDDDDDNN DLEELKVKAS PITNDGEDEF VPSDGLDKDE YTFSPGKSKA TPEKSLHDKK  1440
SQDFGNLFSF PSYSQKSEDD SAKFDSNEED SASVFSPSFG LKQTDKVPSK TVAAKKGKPS  1500
SDTVPKPKRA PKQKKVVEAV NSDSDSEFGI PKKTTTPKGK GRGAKKRKAS GSENEGDYNP  1560
GRKTSKTTSK KPKKTSFDQD SDVDIFPSDF PTEPPSLPRT GRARKEVKYF AESDEEEDDV  1620
DFAMFN                                                             1626

Coding Sequence

Download: Fasta
ATGGCCAAGT CGGGTGGCTG CGGCGCGGGA GCCGGCGTGG GCGGCGGCAA CGGGGCACTG    60
ACCTGGGTGA CTCTTTTTGA TCAGAACAAT GCTGCAAAAA AAGAAGAGTC AGAAACTGCC   120
AACAAAAATG ATTCTTCAAA GAAGTTGTCT GTTGAGAGAG TGTATCAGAA GAAGACACAA   180
CTTGAACACA TTCTTCTTCG TCCTGATACA TATATTGGGT CAGTGGAGCC ATTGACGCAG   240
TTCATGTGGG TGTATGATGA AGATGTAGGA ATGAATTGCA GGGAGGTTAC CTTTGTGCCA   300
GGTTTATACA AGATCTTTGA TGAAATTTTG GTTAATGCTG CTGACAATAA ACAGAGGGAT   360
AAGAACATGA CTTGTATTAA AGTTTCTATT GATCCTGAAT CTAACATTAT AAGCATTTGG   420
AATAATGGGA AAGGCATTCC AGTAGTAGAA CACAAGGTAG AGAAAGTTTA TGTTCCTGCT   480
TTAATTTTTG GACAGCTTTT AACATCCAGT AACTATGATG ATGATGAGAA AAAAGTTACA   540
GGTGGTCGTA ATGGTTATGG TGCAAAACTT TGTAATATTT TCAGTACAAA GTTTACAGTA   600
GAAACAGCTT GCAAAGAATA CAAACACAGT TTTAAGCAGA CATGGATGAA TAATATGATG   660
AAGACTTCTG AAGCCAAAAT TAAACATTTT GATGGTGAAG ATTACACATG CATAACATTC   720
CAACCAGATC TGTCCAAATT TAAGATGGAA AAACTTGACA AGGATATTGT GGCCCTCATG   780
ACTAGAAGGG CATATGATTT GGCTGGTTCG TGTAGAGGGG TCAAGGTCAT GTTTAATGGA   840
AAGAAATTGC CTGTAAATGG ATTTCGCAGT TATGTAGATC TTTATGTGAA AGACAAATTG   900
GATGAAACTG GGGTGGCCCT GAAAGTTATT CATGAGCTTG CAAATGAAAG ATGGGATGTT   960
TGTCTCACAT TGAGTGAAAA AGGATTCCAG CAAATCAGCT TTGTAAATAG TATTGCAACT  1020
ACAAAAGGTG GACGGCACGT GGATTATGTG GTAGATCAAG TTGTTGGTAA ACTGATTGAA  1080
GTAGTTAAGA AAAAGAACAA AGCTGGTGTA TCAGTGAAAC CATTTCAAGT AAAAAACCAT  1140
ATATGGGTTT TTATTAATTG CCTTATTGAA AATCCAACTT TTGATTCTCA GACTAAGGAA  1200
AACATGACTC TGCAGCCCAA AAGTTTTGGG TCTAAATGCC AGCTGTCAGA AAAATTTTTT  1260
AAAGCAGCCT CTAATTGTGG CATTGTAGAA AGTATCCTGA ACTGGGTGAA ATTTAAGGCT  1320
CAGACTCAGC TGAATAAGAA GTGTTCATCA GTAAAATACA GTAAAATCAA AGGTATTCCC  1380
AAACTGGATG ATGCTAATGA TGCTGGTGGT AAACATTCCC TGGAGTGTAC ACTGATATTA  1440
ACAGAGGGAG ACTCTGCCAA ATCACTGGCT GTGTCTGGAT TAGGTGTGAT TGGACGAGAC  1500
AGATACGGAG TTTTTCCACT CAGGGGCAAA ATTCTTAATG TACGGGAAGC TTCTCATAAA  1560
CAGATCATGG AAAATGCTGA AATAAATAAT ATTATTAAAA TAGTTGGTCT ACAATATAAG  1620
AAAAGTTACG ATGATGCAGA ATCTCTGAAA ACCTTACGCT ATGGAAAGAT TATGATTATG  1680
ACCGATCAGG ATCAAGATGG TTCTCACATA AAAGGCCTGC TTATTAATTT CATCCATCAC  1740
AATTGGCCAT CACTTTTGAA GCATGGTTTT CTTGAAGAGT TCATTACTCC TATTGTAAAG  1800
GCAAGCAAAA ATAAGCAGGA ACTTTCCTTC TACAGTATTC CTGAATTTGA CGAATGGAAA  1860
AAACATATAG AAAACCAGAA AGCCTGGAAA ATAAAGTACT ATAAAGGATT GGGTACTAGT  1920
ACAGCTAAAG AAGCAAAGGA ATATTTTGCT GATATGGAAA GGCATCGCAT CTTGTTTAGA  1980
TATGCTGGTC CTGAAGATGA TGCTGCCATT ACCTTGGCAT TTAGTAAGAA GAAGATTGAT  2040
GACAGAAAAG AATGGTTAAC AAATTTTATG GAAGACCGGA GACAGCGTAG GCTACATGGC  2100
TTACCAGAGC AATTTTTATA TGGTACTGCA ACAAAGCATT TGACTTATAA TGATTTCATC  2160
AACAAGGAAT TGATTCTCTT CTCAAACTCA GACAATGAAA GATCTATACC ATCTCTTGTT  2220
GATGGCTTTA AACCTGGCCA GCGGAAAGTT TTATTTACCT GTTTCAAGAG GAATGATAAA  2280
CGTGAAGTAA AAGTTGCCCA GTTGGCTGGC TCTGTTGCTG AGATGTCGGC TTATCATCAT  2340
GGAGAACAAG CATTGATGAT GACTATTGTG AATTTGGCTC AGAACTTTGT GGGAAGTAAC  2400
AACATTAACT TGCTTCAGCC TATTGGTCAG TTTGGAACTC GGCTTCATGG TGGCAAAGAT  2460
GCTGCAAGCC CTCGTTATAT TTTCACAATG TTAAGCACTT TAGCAAGGCT ACTTTTTCCT  2520
GCTGTGGATG ACAACCTCCT TAAGTTCCTT TATGATGATA ATCAACGTGT AGAGCCTGAG  2580
TGGTATATTC CTATAATTCC CATGGTTTTA ATAAATGGTG CTGAGGGCAT TGGTACTGGA  2640
TGGGCTTGTA AACTACCCAA CTATGATGCT AGGGAAATTG TGAACAATGT CAGACGAATG  2700
CTAGATGGCC TGGATCCTCA TCCCATGCTT CCAAACTACA AAAACTTTAA AGGCACGATT  2760
CAAGAACTTG GTCAAAACCA GTATGCAGTC AGTGGTGAAA TATTTGTAGT GGACAGAAAC  2820
ACAGTAGAAA TTACAGAGCT TCCAGTTAGA ACTTGGACAC AGGTATATAA AGAACAGGTT  2880
TTAGAACCTA TGCTAAATGG AACAGATAAA ACACCAGCAT TAATTTCTGA TTATAAAGAA  2940
TATCATACTG ACACAACTGT GAAATTTGTG GTGAAAATGA CTGAAGAGAA ACTAGCACAA  3000
GCAGAAGCTG CTGGACTGCA TAAAGTTTTT AAACTTCAAA CTACTCTTAC TTGTAATTCC  3060
ATGGTACTTT TTGATCATAT GGGATGTCTG AAGAAATATG AAACTGTGCA AGACATTCTG  3120
AAAGAATTCT TTGATTTACG ATTAAGTTAT TACGGTTTAC GTAAGGAGTG GCTTGTGGGA  3180
ATGTTGGGAG CAGAATCTAC AAAGCTTAAC AATCAAGCCC GTTTCATTTT AGAGAAGATA  3240
CAAGGGAAAA TTACTATAGA GAATAGGTCA AAGAAAGATT TGATTCAAAT GTTAGTCCAG  3300
AGAGGTTATG AATCTGACCC AGTGAAAGCC TGGAAAGAAG CACAAGAAAA GGCAGCAGAA  3360
GAGGATGAAA CACAAAACCA GCATGATGAT AGTTCCTCCG ATTCAGGAAC TCCTTCAGGC  3420
CCAGATTTTA ATTATATTTT AAATATGTCT CTGTGGTCTC TTACTAAAGA AAAAGTTGAA  3480
GAACTGATTA AACAGAGAGA TGCAAAAGGG CGAGAGGTCA ATGATCTTAA AAGAAAATCT  3540
CCTTCAGATC TTTGGAAAGA GGATTTAGCG GCATTTGTTG AAGAACTGGA TAAAGTGGAA  3600
TCTCAAGAAC GAGAAGATGT TCTGGCTGGA ATGTCTGGAA AAGCAATTAA AGGTAAAGTT  3660
GGCAAACCTA AGGTGAAGAA ACTCCAGTTG GAAGAGACAA TGCCCTCACC TTATGGCAGA  3720
AGAATAATTC CTGAAATTAC AGCTATGAAG GCAGATGCCA GCAAAAAGTT GCTGAAGAAG  3780
AAGAAGGGTG ATCTTGATAC TGCAGCAGTA AAAGTGGAAT TTGATGAAGA ATTCAGTGGA  3840
GCACCAGTAG AAGGTGCAGG AGAAGAGGCA TTGACTCCAT CAGTTCCTAT AAATAAAGGT  3900
CCCAAACCTA AGAGGGAGAA GAAGGAGCCT GGTACCAGAG TGAGAAAAAC ACCTACATCA  3960
TCTGGTAAAC CTAGTGCAAA GAAAGTGAAG AAACGGAATC CTTGGTCAGA TGATGAATCC  4020
AAGTCAGAAA GTGATTTGGA AGAAACAGAA CCTGTGGTTA TTCCAAGAGA TTCTTTGCTT  4080
AGGAGAGCAG CAGCCGAAAG ACCTAAATAC ACATTTGATT TCTCAGAAGA AGAGGATGAT  4140
GATGCTGATG ATGATGATGA TGACAATAAT GATTTAGAGG AATTGAAAGT TAAAGCATCT  4200
CCCATAACAA ATGATGGGGA AGATGAATTT GTTCCTTCAG ATGGGTTAGA TAAAGATGAA  4260
TATACATTTT CACCAGGCAA ATCAAAAGCC ACTCCAGAAA AATCTTTGCA TGACAAAAAA  4320
AGTCAGGATT TTGGAAATCT CTTCTCATTT CCTTCATATT CTCAGAAGTC AGAAGATGAT  4380
TCAGCTAAAT TTGACAGTAA TGAAGAAGAT TCTGCTTCTG TTTTTTCACC ATCATTTGGT  4440
CTGAAACAGA CAGATAAAGT TCCAAGTAAA ACGGTAGCTG CTAAAAAGGG AAAACCGTCT  4500
TCAGATACAG TCCCTAAGCC CAAGAGAGCC CCAAAACAGA AGAAAGTAGT AGAGGCTGTA  4560
AACTCTGACT CGGATTCAGA ATTTGGCATT CCAAAGAAGA CTACAACACC AAAAGGTAAA  4620
GGCCGAGGGG CAAAGAAAAG GAAAGCATCT GGCTCTGAAA ATGAAGGCGA TTATAACCCT  4680
GGCAGGAAAA CATCCAAAAC AACAAGCAAG AAACCGAAGA AGACATCTTT TGATCAGGAT  4740
TCAGATGTGG ACATCTTCCC CTCAGACTTC CCTACTGAGC CACCTTCTCT GCCACGAACC  4800
GGTCGGGCTA GGAAAGAAGT AAAATATTTT GCAGAGTCTG ATGAAGAAGA AGATGATGTT  4860
GATTTTGCAA TGTTTAATTA A                                            4881