Entry HUMAN11734 (EST1A_HUMAN)

E Homo sapiens


General Information

Description
SMG6, nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:17809]
Organism
HUMAN - Homo sapiens (Taxon-ID: 9606)
Locus
17join(complement(2303633..2303720), complement(2298906..2300664), complement(2297863..2298055), complement(2297243..2297353), complement(2292871..2292977), complement(2292552..2292630), complement(2283625..2283735), complement(2282647..2282859), complement(2244658..2244719), complement(2236492..2236637), complement(2188399..2188515), complement(2186663..2186831), complement(2172658..2172859), complement(2085725..2085901), complement(2081810..2081956), complement(2068778..2068931), complement(2065468..2065679), complement(2065073..2065154), complement(2061492..2061622))
Number of exons
19

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

Download: Fasta
MAEGLERVRI SASELRGILA TLAPQAGSRE NMKELKEARP RKDNRRPDLE IYKPGLSRLR    60
NKPKIKEPPG SEEFKDEIVN DRDCSAVENG TQPVKDVCKE LNNQEQNGPI DPENNRGQES   120
FPRTAGQEDR SLKIIKRTKK PDLQIYQPGR RLQTVSKESA SRVEEEEVLN QVEQLRVEED   180
ECRGNVAKEE VANKPDRAEI EKSPGGGRVG AAKGEKGKRM GKGEGVRETH DDPARGRPGS   240
AKRYSRSDKR RNRYRTRSTS SAGSNNSAEG AGLTDNGCRR RRQDRTKERP RLKKQVSVSS   300
TDSLDEDRID EPDGLGPRRS SERKRHLERN WSGRGEGEQK NSAKEYRGTL RVTFDAEAMN   360
KESPMVRSAR DDMDRGKPDK GLSSGGKGSE KQESKNPKQE LRGRGRGILI LPAHTTLSVN   420
SAGSPESAPL GPRLLFGSGS KGSRSWGRGG TTRRLWDPNN PDQKPALKTQ TPQLHFLDTD   480
DEVSPTSWGD SRQAQASYYK FQNSDNPYYY PRTPGPASQY PYTGYNPLQY PVGPTNGVYP   540
GPYYPGYPTP SGQYVCSPLP TSTMSPEEVE QHMRNLQQQE LHRLLRVADN QELQLSNLLS   600
RDRISPEGLE KMAQLRAELL QLYERCILLD IEFSDNQNVD QILWKNAFYQ VIEKFRQLVK   660
DPNVENPEQI RNRLLELLDE GSDFFDSLLQ KLQVTYKFKL EDYMDGLAIR SKPLRKTVKY   720
ALISAQRCMI CQGDIARYRE QASDTANYGK ARSWYLKAQH IAPKNGRPYN QLALLAVYTR   780
RKLDAVYYYM RSLAASNPIL TAKESLMSLF EETKRKAEQM EKKQHEEFDL SPDQWRKGKK   840
STFRHVGDDT TRLEIWIHPS HPRSSQGTES GKDSEQENGL GSLSPSDLNK RFILSFLHAH   900
GKLFTRIGME TFPAVAEKVL KEFQVLLQHS PSPIGSTRML QLMTINMFAV HNSQLKDCFS   960
EECRSVIQEQ AAALGLAMFS LLVRRCTCLL KESAKAQLSS PEDQDDQDDI KVSSFVPDLK  1020
ELLPSVKVWS DWMLGYPDTW NPPPTSLDLP SHVAVDVWST LADFCNILTA VNQSEVPLYK  1080
DPDDDLTLLI LEEDRLLSGF VPLLAAPQDP CYVEKTSDKV IAADCKRVTV LKYFLEALCG  1140
QEEPLLAFKG GKYVSVAPVP DTMGKEMGSQ EGTRLEDEEE DVVIEDFEED SEAEGSGGED  1200
DIRELRAKKL ALARKIAEQQ RRQEKIQAVL EDHSQMRQME LEIRPLFLVP DTNGFIDHLA  1260
SLARLLESRK YILVVPLIVI NELDGLAKGQ ETDHRAGGYA RVVQEKARKS IEFLEQRFES  1320
RDSCLRALTS RGNELESIAF RSEDITGQLG NNDDLILSCC LHYCKDKAKD FMPASKEEPI  1380
RLLREVVLLT DDRNLRVKAL TRNVPVRDIP AFLTWAQVG                         1419

Coding Sequence

Download: Fasta
ATGGCGGAAG GGCTGGAGCG TGTGCGGATC TCCGCGTCGG AGCTGCGCGG GATCCTGGCT    60
ACTCTGGCCC CGCAGGCCGG GAGCAGAGAA AACATGAAGG AATTAAAGGA GGCCAGGCCG   120
CGCAAAGATA ACAGGCGTCC AGATCTGGAA ATCTATAAGC CTGGCCTTTC TCGGCTAAGG   180
AACAAGCCCA AAATCAAGGA ACCCCCTGGG AGTGAGGAAT TCAAAGATGA AATTGTTAAT   240
GACCGAGATT GCTCTGCTGT TGAAAATGGT ACACAGCCCG TTAAAGATGT CTGCAAGGAA   300
CTGAACAACC AAGAGCAGAA TGGTCCTATA GACCCAGAAA ATAATCGGGG ACAAGAATCC   360
TTTCCTAGGA CTGCTGGACA AGAGGATCGT AGTCTAAAAA TTATCAAAAG AACAAAGAAA   420
CCCGACCTGC AGATCTATCA GCCTGGACGA CGTTTGCAGA CTGTTAGCAA AGAATCCGCC   480
AGTCGGGTGG AGGAGGAAGA AGTCCTCAAC CAGGTAGAAC AACTGAGAGT AGAGGAAGAT   540
GAGTGTAGGG GAAATGTTGC GAAGGAGGAA GTTGCGAATA AACCAGACAG GGCTGAGATA   600
GAAAAGAGCC CAGGTGGTGG GAGAGTAGGG GCTGCAAAAG GAGAAAAAGG AAAGAGGATG   660
GGAAAAGGGG AGGGGGTGAG GGAAACCCAC GACGACCCAG CCCGCGGGAG GCCGGGCTCC   720
GCAAAGCGCT ACTCCCGCTC AGACAAACGA AGGAATCGCT ACCGCACGCG CAGCACCAGC   780
TCAGCTGGCA GCAACAACAG CGCTGAGGGA GCTGGCCTGA CGGATAATGG ATGTCGCCGC   840
CGCCGACAGG ATAGGACCAA GGAGAGGCCA CGACTGAAGA AGCAAGTGTC TGTGTCCTCA   900
ACCGATTCCT TAGACGAGGA CAGAATTGAT GAGCCTGATG GATTAGGACC CAGGAGAAGT   960
TCAGAAAGGA AGAGACATTT AGAAAGAAAC TGGTCTGGCC GTGGGGAGGG TGAGCAGAAA  1020
AACAGTGCTA AAGAATATCG AGGCACTCTT CGTGTCACTT TCGATGCAGA AGCCATGAAC  1080
AAAGAGTCTC CCATGGTGAG GTCAGCCAGG GATGATATGG ATAGAGGAAA GCCTGACAAA  1140
GGCTTGAGCA GTGGGGGCAA AGGCTCTGAG AAGCAGGAGT CCAAAAACCC GAAACAAGAA  1200
CTTCGGGGTC GTGGTCGTGG CATTCTGATT TTGCCTGCCC ATACCACCCT ATCTGTCAAT  1260
TCAGCAGGTT CTCCAGAGTC CGCGCCTTTG GGACCTCGGC TTTTGTTTGG ATCTGGTAGT  1320
AAGGGATCTC GGAGTTGGGG CCGTGGAGGC ACCACACGCC GATTGTGGGA CCCAAACAAT  1380
CCTGATCAGA AACCTGCTCT AAAGACTCAG ACGCCCCAGC TACATTTCTT GGACACTGAT  1440
GATGAAGTCA GCCCTACATC TTGGGGTGAC TCACGCCAGG CTCAGGCATC TTACTATAAG  1500
TTTCAAAACT CTGACAACCC CTATTATTAC CCCCGGACAC CAGGCCCTGC CTCCCAGTAT  1560
CCCTATACGG GCTATAACCC TCTACAGTAC CCAGTGGGCC CTACGAATGG TGTGTACCCA  1620
GGGCCTTACT ACCCAGGCTA CCCGACTCCG TCAGGACAGT ATGTGTGTAG CCCTCTACCT  1680
ACCAGCACCA TGAGTCCCGA GGAGGTAGAG CAGCACATGA GGAACCTGCA GCAACAGGAG  1740
CTGCACAGGC TTCTCCGGGT GGCTGACAAC CAGGAACTGC AGCTCAGCAA CCTGCTCTCC  1800
AGGGACCGCA TCAGTCCGGA GGGCCTGGAG AAGATGGCGC AACTCAGAGC TGAACTGCTG  1860
CAGCTATATG AGCGCTGTAT TCTATTAGAT ATTGAGTTCT CTGATAATCA GAATGTGGAT  1920
CAGATCCTGT GGAAGAATGC TTTCTATCAG GTGATTGAGA AGTTCAGGCA ACTTGTCAAG  1980
GATCCGAATG TTGAGAACCC AGAACAGATT CGGAACAGAC TTTTGGAGCT CTTGGATGAG  2040
GGTAGTGACT TCTTTGATAG TTTGCTTCAG AAGCTGCAGG TTACTTACAA GTTCAAACTG  2100
GAAGACTACA TGGATGGTCT TGCCATTCGC AGCAAGCCAT TACGCAAGAC AGTAAAATAT  2160
GCCTTGATCA GTGCCCAGCG ATGCATGATA TGCCAAGGAG ATATTGCTAG GTACCGGGAG  2220
CAAGCCAGTG ATACAGCGAA TTATGGGAAA GCACGCAGTT GGTACCTGAA GGCCCAGCAC  2280
ATTGCTCCCA AGAATGGGCG CCCCTATAAC CAGTTGGCTT TGCTGGCAGT GTATACGAGG  2340
AGGAAGCTTG ACGCTGTCTA TTACTATATG CGCAGTTTAG CTGCCAGCAA CCCTATCCTG  2400
ACTGCCAAGG AGAGTCTCAT GAGCTTGTTT GAAGAGACCA AGCGGAAGGC AGAACAGATG  2460
GAAAAGAAGC AACATGAGGA ATTTGACCTG AGCCCTGACC AGTGGCGGAA AGGAAAGAAG  2520
TCTACTTTCC GGCATGTTGG AGATGACACC ACTCGCCTGG AGATCTGGAT TCATCCATCC  2580
CATCCACGGT CTTCCCAGGG CACTGAGTCT GGGAAGGATT CTGAGCAAGA GAATGGGCTG  2640
GGCAGCCTGA GTCCCAGTGA TCTGAACAAA AGGTTCATCC TCAGTTTTCT CCATGCCCAT  2700
GGGAAGCTGT TTACCCGGAT TGGGATGGAG ACATTCCCTG CAGTGGCTGA GAAGGTCCTC  2760
AAGGAGTTCC AGGTGTTACT GCAGCACAGC CCCTCTCCCA TTGGAAGTAC CCGCATGCTG  2820
CAGCTTATGA CCATCAATAT GTTTGCAGTA CACAACTCCC AGCTGAAAGA CTGCTTCTCG  2880
GAGGAGTGCC GCTCTGTGAT CCAGGAACAA GCCGCAGCTC TGGGCTTGGC CATGTTTTCT  2940
CTACTGGTCC GCCGCTGCAC CTGCTTACTT AAGGAGTCCG CCAAAGCTCA GCTGTCCTCT  3000
CCTGAGGACC AGGATGACCA AGACGACATC AAGGTGTCTT CCTTTGTCCC GGACCTGAAG  3060
GAGCTGCTCC CCAGTGTCAA AGTCTGGTCA GATTGGATGC TCGGCTACCC GGACACCTGG  3120
AATCCTCCTC CCACATCCCT GGATCTGCCC TCGCATGTTG CTGTGGATGT ATGGTCGACG  3180
CTGGCTGATT TCTGTAACAT ACTGACTGCA GTGAATCAGT CTGAGGTGCC ACTGTACAAG  3240
GACCCGGATG ATGACCTCAC CCTTCTTATC CTGGAAGAGG ATCGGCTTCT CTCGGGCTTT  3300
GTCCCCTTGC TGGCTGCCCC TCAGGACCCC TGCTACGTGG AGAAAACCTC GGATAAGGTT  3360
ATTGCAGCTG ACTGCAAAAG GGTCACAGTG CTGAAGTATT TTCTGGAAGC CCTTTGTGGA  3420
CAAGAAGAGC CTCTGCTGGC ATTCAAGGGT GGAAAGTATG TGTCAGTGGC ACCCGTCCCA  3480
GACACCATGG GAAAGGAAAT GGGAAGCCAA GAGGGAACAC GACTGGAAGA TGAGGAGGAG  3540
GATGTGGTGA TTGAAGACTT TGAGGAAGAT TCAGAGGCTG AAGGCAGCGG AGGCGAGGAT  3600
GACATCAGGG AGCTTCGGGC CAAGAAGCTG GCTCTGGCCA GGAAGATAGC TGAGCAGCAG  3660
CGTCGCCAGG AAAAGATCCA GGCTGTCCTG GAGGACCACA GTCAGATGAG GCAGATGGAG  3720
CTCGAAATCA GACCTTTGTT CCTCGTACCA GACACCAACG GCTTCATTGA CCACCTGGCC  3780
AGTCTGGCGC GGCTGCTGGA GAGCAGGAAG TACATCCTGG TGGTGCCCCT CATCGTGATC  3840
AATGAGCTGG ACGGCCTGGC CAAGGGGCAG GAGACAGACC ACCGGGCTGG GGGCTACGCC  3900
CGTGTGGTAC AAGAGAAGGC CCGCAAGTCC ATCGAGTTCC TCGAGCAGCG ATTCGAGAGT  3960
CGGGACTCTT GCCTGCGAGC CCTGACCAGC CGTGGCAATG AACTCGAATC CATCGCCTTC  4020
CGCAGTGAGG ACATCACTGG CCAGCTGGGT AACAACGATG ATCTCATCCT GTCCTGCTGC  4080
CTCCACTACT GCAAAGACAA GGCTAAGGAC TTCATGCCCG CCAGCAAAGA GGAGCCAATC  4140
CGGCTACTGC GGGAGGTGGT GCTGTTGACG GATGACCGGA ACCTGCGTGT GAAGGCGCTC  4200
ACAAGGAATG TTCCTGTACG GGACATCCCA GCCTTCCTCA CGTGGGCCCA GGTGGGCTGA  4260