Entry HUMAN08614 (NUMB_HUMAN)

E Homo sapiens


General Information

Description
NUMB, endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8060]
Organism
HUMAN - Homo sapiens (Taxon-ID: 9606)
Locus
14join(complement(73355626..73355751), complement(73323130..73323204), complement(73316390..73316422), complement(73297211..73297285), complement(73292734..73292874), complement(73287110..73287314), complement(73284081..73284374), complement(73282359..73282505), complement(73279281..73279424), complement(73276578..73277293))
Number of exons
10

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

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MNKLRQSFRR KKDVYVPEAS RPHQWQTDEE GVRTGKCSFP VKYLGHVEVD ESRGMHICED    60
AVKRLKAERK FFKGFFGKTG KKAVKAVLWV SADGLRVVDE KTKDLIVDQT IEKVSFCAPD   120
RNFDRAFSYI CRDGTTRRWI CHCFMAVKDT GERLSHAVGC AFAACLERKQ KREKECGVTA   180
TFDASRTTFT REGSFRVTTA TEQAEREEIM KQMQDAKKAE TDKIVVGSSV APGNTAPSPS   240
SPTSPTSDAT TSLEMNNPHA IPRRHAPIEQ LARQGSFRGF PALSQKMSPF KRQLSLRINE   300
LPSTMQRKTD FPIKNAVPEV EGEAESISSL CSQITNAFST PEDPFSSAPM TKPVTVVAPQ   360
SPTFQANGTD SAFHVLAKPA HTALAPVAMP VRETNPWAHA PDAANKEIAA TCSGTEWGQS   420
SGAASPGLFQ AGHRRTPSEA DRWLEEVSKS VRAQQPQASA APLQPVLQPP PPTAISQPAS   480
PFQGNAFLTS QPVPVGVVPA LQPAFVPAQS YPVANGMPYP APNVPVVGIT PSQMVANVFG   540
TAGHPQAAHP HQSPSLVRQQ TFPHYEASSA TTSPFFKPPA QHLNGSAAFN GVDDGRLASA   600
DRHTEVPTGT CPVDPFEAQW AALENKSKQR TNPSPTNPFS SDLQKTFEIE L            651

Coding Sequence

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ATGAACAAAT TACGGCAAAG TTTTAGGAGA AAGAAGGATG TTTATGTTCC AGAGGCCAGT    60
CGTCCACATC AGTGGCAGAC AGATGAAGAA GGCGTTCGCA CCGGAAAATG TAGCTTCCCG   120
GTTAAGTACC TTGGCCATGT AGAAGTTGAT GAATCAAGAG GAATGCACAT CTGTGAAGAT   180
GCTGTAAAAA GATTGAAAGC TGAAAGGAAG TTCTTCAAAG GCTTCTTTGG AAAAACTGGA   240
AAGAAAGCAG TTAAAGCAGT TCTGTGGGTC TCAGCAGATG GACTCAGAGT TGTGGATGAA   300
AAAACTAAGG ACCTCATAGT TGACCAGACG ATAGAGAAAG TTTCTTTCTG TGCCCCAGAC   360
AGGAACTTTG ATAGAGCCTT TTCTTACATA TGCCGTGATG GCACCACTCG TCGCTGGATC   420
TGTCACTGCT TCATGGCTGT CAAGGACACA GGTGAAAGGT TGAGCCATGC AGTAGGCTGT   480
GCTTTTGCAG CCTGTTTAGA GCGCAAGCAG AAGCGGGAGA AGGAATGTGG AGTGACTGCT   540
ACTTTTGATG CTAGTCGGAC CACTTTTACA AGAGAAGGAT CATTCCGTGT CACAACAGCC   600
ACTGAACAAG CAGAAAGAGA GGAGATCATG AAACAAATGC AAGATGCCAA GAAAGCTGAA   660
ACAGATAAGA TAGTCGTTGG TTCATCAGTT GCCCCTGGCA ACACTGCCCC ATCCCCATCC   720
TCTCCCACCT CTCCTACTTC TGATGCCACG ACCTCTCTGG AGATGAACAA TCCTCATGCC   780
ATCCCACGCC GGCATGCTCC AATTGAACAG CTTGCTCGCC AAGGCTCTTT CCGAGGTTTT   840
CCTGCTCTTA GCCAGAAGAT GTCACCCTTT AAACGCCAAC TATCCCTACG CATCAATGAG   900
TTGCCTTCCA CTATGCAGAG GAAGACTGAT TTCCCCATTA AAAATGCAGT GCCAGAAGTA   960
GAAGGGGAGG CAGAGAGCAT CAGCTCCCTG TGCTCACAGA TCACCAATGC CTTCAGCACA  1020
CCTGAGGACC CCTTCTCATC TGCTCCGATG ACCAAACCAG TGACAGTGGT GGCACCACAA  1080
TCTCCTACCT TCCAAGCTAA TGGCACTGAC TCAGCCTTCC ATGTGCTTGC TAAGCCAGCC  1140
CATACTGCTC TAGCACCCGT AGCAATGCCT GTGCGTGAAA CCAACCCTTG GGCCCATGCC  1200
CCTGATGCTG CTAACAAGGA AATTGCAGCC ACATGTTCGG GGACCGAGTG GGGTCAATCT  1260
TCTGGTGCTG CCTCTCCAGG TCTCTTCCAG GCCGGTCATA GACGTACTCC CTCTGAGGCC  1320
GACCGATGGT TAGAAGAGGT GTCTAAGAGC GTCCGGGCTC AGCAGCCCCA GGCCTCAGCT  1380
GCTCCTCTGC AGCCAGTTCT CCAGCCTCCT CCACCCACTG CCATCTCCCA GCCAGCATCA  1440
CCTTTCCAAG GGAATGCATT CCTCACCTCT CAGCCTGTGC CAGTGGGTGT GGTCCCAGCC  1500
CTGCAACCAG CCTTTGTCCC TGCCCAGTCC TATCCTGTGG CCAATGGAAT GCCCTATCCA  1560
GCCCCTAATG TGCCTGTGGT GGGCATCACT CCCTCCCAGA TGGTGGCCAA CGTATTTGGC  1620
ACTGCAGGCC ACCCTCAGGC TGCCCATCCC CATCAGTCAC CCAGCCTGGT CAGGCAGCAG  1680
ACATTCCCTC ACTACGAGGC AAGCAGTGCT ACCACCAGTC CCTTCTTTAA GCCTCCTGCT  1740
CAGCACCTCA ACGGTTCTGC AGCTTTCAAT GGTGTAGATG ATGGCAGGTT GGCCTCAGCA  1800
GACAGGCATA CAGAGGTTCC TACAGGCACC TGCCCAGTGG ATCCTTTTGA AGCCCAGTGG  1860
GCTGCATTAG AAAATAAGTC CAAGCAGCGT ACTAATCCCT CCCCTACCAA CCCTTTCTCC  1920
AGTGACTTAC AGAAGACGTT TGAAATTGAA CTTTAA                            1956