Entry HUMAN01294 (DPYD_HUMAN)

E Homo sapiens


General Information

Description
dihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012]
Organism
HUMAN - Homo sapiens (Taxon-ID: 9606)
Locus
1join(complement(97920884..97920922), complement(97883264..97883374), complement(97828114..97828196), complement(97740392..97740479), complement(97721510..97721671), complement(97699351..97699547), complement(97691717..97691798), complement(97679095..97679182), complement(97595059..97595166), complement(97593218..97593387), complement(97573760..97573970), complement(97549560..97549744), complement(97515726..97515941), complement(97450059..97450223), complement(97382393..97382461), complement(97373561..97373644), complement(97306177..97306297), complement(97305259..97305378), complement(97234852..97234994), complement(97193069..97193248), complement(97098489..97098632), complement(97082330..97082470), complement(97078976..97079146))
Number of exons
23

IDs and Cross-references

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Domain Architecture

Gene Ontology

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Protein Sequence

Download: Fasta
MAPVLSKDSA DIESILALNP RTQTHATLCS TSAKKLDKKH WKRNPDKNCF NCEKLENNFD    60
DIKHTTLGER GALREAMRCL KCADAPCQKS CPTNLDIKSF ITSIANKNYY GAAKMIFSDN   120
PLGLTCGMVC PTSDLCVGGC NLYATEEGPI NIGGLQQFAT EVFKAMSIPQ IRNPSLPPPE   180
KMSEAYSAKI ALFGAGPASI SCASFLARLG YSDITIFEKQ EYVGGLSTSE IPQFRLPYDV   240
VNFEIELMKD LGVKIICGKS LSVNEMTLST LKEKGYKAAF IGIGLPEPNK DAIFQGLTQD   300
QGFYTSKDFL PLVAKGSKAG MCACHSPLPS IRGVVIVLGA GDTAFDCATS ALRCGARRVF   360
IVFRKGFVNI RAVPEEMELA KEEKCEFLPF LSPRKVIVKG GRIVAMQFVR TEQDETGKWN   420
EDEDQMVHLK ADVVISAFGS VLSDPKVKEA LSPIKFNRWG LPEVDPETMQ TSEAWVFAGG   480
DVVGLANTTV ESVNDGKQAS WYIHKYVQSQ YGASVSAKPE LPLFYTPIDL VDISVEMAGL   540
KFINPFGLAS ATPATSTSMI RRAFEAGWGF ALTKTFSLDK DIVTNVSPRI IRGTTSGPMY   600
GPGQSSFLNI ELISEKTAAY WCQSVTELKA DFPDNIVIAS IMCSYNKNDW TELAKKSEDS   660
GADALELNLS CPHGMGERGM GLACGQDPEL VRNICRWVRQ AVQIPFFAKL TPNVTDIVSI   720
ARAAKEGGAN GVTATNTVSG LMGLKSDGTP WPAVGIAKRT TYGGVSGTAI RPIALRAVTS   780
IARALPGFPI LATGGIDSAE SGLQFLHSGA SVLQVCSAIQ NQDFTVIEDY CTGLKALLYL   840
KSIEELQDWD GQSPATVSHQ KGKPVPRIAE LMDKKLPSFG PYLEQRKKII AENKIRLKEQ   900
NVAFSPLKRN CFIPKRPIPT IKDVIGKALQ YLGTFGELSN VEQVVAMIDE EMCINCGKCY   960
MTCNDSGYQA IQFDPETHLP TITDTCTGCT LCLSVCPIVD CIKMVSRTTP YEPKRGVPLS  1020
VNPVC                                                              1025

Coding Sequence

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ATGGCCCCTG TGCTCAGTAA GGACTCGGCG GACATCGAGA GTATCCTGGC TTTAAATCCT    60
CGAACACAAA CTCATGCAAC TCTGTGTTCC ACTTCGGCCA AGAAATTAGA CAAGAAACAT   120
TGGAAAAGAA ATCCTGATAA GAACTGCTTT AATTGTGAGA AGCTGGAGAA TAATTTTGAT   180
GACATCAAGC ACACGACTCT TGGTGAGCGA GGAGCTCTCC GAGAAGCAAT GAGATGCCTG   240
AAATGTGCAG ATGCCCCGTG TCAGAAGAGC TGTCCAACTA ATCTTGATAT TAAATCATTC   300
ATCACAAGTA TTGCAAACAA GAACTATTAT GGAGCTGCTA AGATGATATT TTCTGACAAC   360
CCACTTGGTC TGACTTGTGG AATGGTATGT CCAACCTCTG ATCTTTGTGT AGGTGGATGC   420
AATTTATATG CCACTGAAGA GGGACCCATT AATATTGGTG GATTGCAGCA ATTTGCTACT   480
GAGGTATTCA AAGCAATGAG TATCCCACAG ATCAGAAATC CTTCGCTGCC TCCCCCAGAA   540
AAAATGTCTG AAGCCTATTC TGCAAAGATT GCTCTTTTTG GTGCTGGGCC TGCAAGTATA   600
AGTTGTGCTT CCTTTTTGGC TCGATTGGGG TACTCTGACA TCACTATATT TGAAAAACAA   660
GAATATGTTG GTGGTTTAAG TACTTCTGAA ATTCCTCAGT TCCGGCTGCC GTATGATGTA   720
GTGAATTTTG AGATTGAGCT AATGAAGGAC CTTGGTGTAA AGATAATTTG CGGTAAAAGC   780
CTTTCAGTGA ATGAAATGAC TCTTAGCACT TTGAAAGAAA AAGGCTACAA AGCTGCTTTC   840
ATTGGAATAG GTTTGCCAGA ACCCAATAAA GATGCCATCT TCCAAGGCCT GACGCAGGAC   900
CAGGGGTTTT ATACATCCAA AGACTTTTTG CCACTTGTAG CCAAAGGCAG TAAAGCAGGA   960
ATGTGCGCCT GTCACTCTCC ATTGCCATCG ATACGGGGAG TCGTGATTGT ACTTGGAGCT  1020
GGAGACACTG CCTTTGACTG TGCAACATCT GCTCTACGTT GTGGAGCTCG CCGTGTGTTC  1080
ATCGTCTTCA GAAAAGGCTT TGTTAATATA AGAGCTGTCC CTGAGGAGAT GGAACTTGCT  1140
AAGGAAGAAA AGTGTGAATT TCTGCCATTC CTGTCCCCAC GGAAGGTTAT AGTAAAAGGT  1200
GGGAGAATTG TTGCTATGCA GTTTGTTCGG ACAGAGCAAG ATGAAACTGG AAAATGGAAT  1260
GAAGATGAAG ATCAGATGGT CCATCTGAAA GCCGATGTGG TCATCAGTGC CTTTGGTTCA  1320
GTTCTGAGTG ATCCTAAAGT AAAAGAAGCC TTGAGCCCTA TAAAATTTAA CAGATGGGGT  1380
CTCCCAGAAG TAGATCCAGA AACTATGCAA ACTAGTGAAG CATGGGTATT TGCAGGTGGT  1440
GATGTCGTTG GTTTGGCTAA CACTACAGTG GAATCGGTGA ATGATGGAAA GCAAGCTTCT  1500
TGGTACATTC ACAAATACGT ACAGTCACAA TATGGAGCTT CCGTTTCTGC CAAGCCTGAA  1560
CTACCCCTCT TTTACACTCC TATTGATCTG GTGGACATTA GTGTAGAAAT GGCCGGATTG  1620
AAGTTTATAA ATCCTTTTGG TCTTGCTAGC GCAACTCCAG CCACCAGCAC ATCAATGATT  1680
CGAAGAGCTT TTGAAGCTGG ATGGGGTTTT GCCCTCACCA AAACTTTCTC TCTTGATAAG  1740
GACATTGTGA CAAATGTTTC CCCCAGAATC ATCCGGGGAA CCACCTCTGG CCCCATGTAT  1800
GGCCCTGGAC AAAGCTCCTT TCTGAATATT GAGCTCATCA GTGAGAAAAC GGCTGCATAT  1860
TGGTGTCAAA GTGTCACTGA ACTAAAGGCT GACTTTCCAG ACAACATTGT GATTGCTAGC  1920
ATTATGTGCA GTTACAATAA AAATGACTGG ACGGAACTTG CCAAGAAGTC TGAGGATTCT  1980
GGAGCAGATG CCCTGGAGTT AAATTTATCA TGTCCACATG GCATGGGAGA AAGAGGAATG  2040
GGCCTGGCCT GTGGGCAGGA TCCAGAGCTG GTGCGGAACA TCTGCCGCTG GGTTAGGCAA  2100
GCTGTTCAGA TTCCTTTTTT TGCCAAGCTG ACCCCAAATG TCACTGATAT TGTGAGCATC  2160
GCAAGAGCTG CAAAGGAAGG TGGTGCCAAT GGCGTTACAG CCACCAACAC TGTCTCAGGT  2220
CTGATGGGAT TAAAATCTGA TGGCACACCT TGGCCAGCAG TGGGGATTGC AAAGCGAACT  2280
ACATATGGAG GAGTGTCTGG GACAGCAATC AGACCTATTG CTTTGAGAGC TGTGACCTCC  2340
ATTGCTCGTG CTCTGCCTGG ATTTCCCATT TTGGCTACTG GTGGAATTGA CTCTGCTGAA  2400
AGTGGTCTTC AGTTTCTCCA TAGTGGTGCT TCCGTCCTCC AGGTATGCAG TGCCATTCAG  2460
AATCAGGATT TCACTGTGAT CGAAGACTAC TGCACTGGCC TCAAAGCCCT GCTTTATCTG  2520
AAAAGCATTG AAGAACTACA AGACTGGGAT GGACAGAGTC CAGCTACTGT GAGTCACCAG  2580
AAAGGGAAAC CAGTTCCACG TATAGCTGAA CTCATGGACA AGAAACTGCC AAGTTTTGGA  2640
CCTTATCTGG AACAGCGCAA GAAAATCATA GCAGAAAACA AGATTAGACT GAAAGAACAA  2700
AATGTAGCTT TTTCACCACT TAAGAGAAAC TGTTTTATCC CCAAAAGGCC TATTCCTACC  2760
ATCAAGGATG TAATAGGAAA AGCACTGCAG TACCTTGGAA CATTTGGTGA ATTGAGCAAC  2820
GTAGAGCAAG TTGTGGCTAT GATTGATGAA GAAATGTGTA TCAACTGTGG TAAATGCTAC  2880
ATGACCTGTA ATGATTCTGG CTACCAGGCT ATACAGTTTG ATCCAGAAAC CCACCTGCCC  2940
ACCATAACCG ACACTTGTAC AGGCTGTACT CTGTGTCTCA GTGTTTGCCC TATTGTCGAC  3000
TGCATCAAAA TGGTTTCCAG GACAACACCT TATGAACCAA AGAGAGGCGT ACCCTTATCT  3060
GTGAATCCGG TGTGTTAA                                                3078