Entry HUMAN12049 (MP2K4_HUMAN)

EHomo sapiens


OMA Group (Proteins all orthologous to each other) ?

OMA Group 574192 ?

mitogen-activated protein kinase kinase


This group has 162 members: E162

Fingerprint: MKSNDCN

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GO:0000166logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedmolecular_function: nucleotide binding
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GO:0051019logo curatedmolecular_function: mitogen-activated protein kinase binding
GO:0000935logo uncuratedcellular_component: division septum
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GO:0005829logo curatedlogo experimentallogo uncuratedcellular_component: cytosol
GO:0030424logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo curatedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedcellular_component: axon
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GO:0043204logo curatedlogo experimentallogo uncuratedcellular_component: perikaryon
GO:0000165logo uncuratedlogo uncuratedlogo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: MAPK cascade
GO:0000187logo curatedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo curatedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo curatedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: activation of MAPK activity
GO:0001934logo curatedlogo experimentallogo uncuratedbiological_process: positive regulation of protein phosphorylation
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GO:0006915logo uncuratedlogo uncuratedbiological_process: apoptotic process
GO:0007165logo curatedbiological_process: signal transduction
GO:0007254logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo curatedlogo experimentallogo curatedlogo uncuratedlogo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: JNK cascade
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GO:0007275logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: multicellular organism development
GO:0009611logo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: response to wounding
GO:0016310logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: phosphorylation
GO:0018108logo uncuratedlogo uncuratedbiological_process: peptidyl-tyrosine phosphorylation
GO:0023014logo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedbiological_process: signal transduction by protein phosphorylation
GO:0030154logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: cell differentiation
GO:0031098logo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedbiological_process: stress-activated protein kinase signaling cascade
GO:0032147logo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedlogo curatedbiological_process: activation of protein kinase activity
GO:0032874logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: positive regulation of stress-activated MAPK cascade
GO:0034393logo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: positive regulation of smooth muscle cell apoptotic process
GO:0035556logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: intracellular signal transduction
GO:0043065logo curatedlogo experimentallogo uncuratedbiological_process: positive regulation of apoptotic process
GO:0043406logo curatedbiological_process: positive regulation of MAP kinase activity
GO:0043410logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: positive regulation of MAPK cascade
GO:0043525logo curatedlogo experimentallogo uncuratedbiological_process: positive regulation of neuron apoptotic process
GO:0043549logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: regulation of kinase activity
GO:0045740logo curatedlogo experimentallogo uncuratedbiological_process: positive regulation of DNA replication
GO:0046330logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: positive regulation of JNK cascade
GO:0046777logo curatedbiological_process: protein autophosphorylation
GO:0048082logo uncuratedlogo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: regulation of adult chitin-containing cuticle pigmentation
GO:0048263logo experimentalbiological_process: determination of dorsal identity
GO:0048468logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: cell development
GO:0048666logo uncuratedlogo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: neuron development
GO:0048869logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: cellular developmental process
GO:0050850logo uncuratedbiological_process: positive regulation of calcium-mediated signaling
GO:0051403logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: stress-activated MAPK cascade
GO:0051770logo curatedlogo experimentallogo uncuratedbiological_process: positive regulation of nitric-oxide synthase biosynthetic process
GO:0060027logo uncuratedlogo uncuratedlogo uncuratedbiological_process: convergent extension involved in gastrulation
GO:0061049logo curatedlogo experimentallogo uncuratedbiological_process: cell growth involved in cardiac muscle cell development
GO:0071260logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: cellular response to mechanical stimulus
GO:0072709logo uncuratedlogo experimentallogo uncuratedbiological_process: cellular response to sorbitol
GO:0080135logo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: regulation of cellular response to stress
GO:2000672logo uncuratedlogo experimentallogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedlogo uncuratedbiological_process: negative regulation of motor neuron apoptotic process