Entry FELCA18021 (M3WFR2)

EFelis catus


General information

Description
lamin A/C [Source:HGNC Symbol;Acc:6636]
Organism
FELCA - Felis catus
Locus
Chromosome F1: join(complement(66799966..66800033), complement(66798680..66798961), (more...)

IDs and Cross-references

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
structural molecule activity (GO:0005198) IEA: GO_REF:002

Cellular component
GO termEvidence and reference
nucleus (GO:0005634) IEA: GO_REF:107
nuclear envelope (GO:0005635) IEA: GO_REF:107
lamin filament (GO:0005638) IEA: GO_REF:107, OMA_Fun:001
nucleoplasm (GO:0005654) IEA: GO_REF:107
intermediate filament (GO:0005882) IEA: GO_REF:002, GO_REF:038
extracellular matrix (GO:0031012) IEA: GO_REF:107
nuclear membrane (GO:0031965) IEA: GO_REF:107
membrane-bounded organelle (GO:0043227) IEA: OMA_Fun:001
intracellular organelle (GO:0043229) IEA: OMA_Fun:001

Biological process
GO termEvidence and reference
nucleus organization (GO:0006997) IEA: GO_REF:107, OMA_Fun:001
nuclear envelope organization (GO:0006998) IEA: GO_REF:107
muscle organ development (GO:0007517) IEA: OMA_Fun:001
negative regulation of cell proliferation (GO:0008285) IEA: GO_REF:107
positive regulation of gene expression (GO:0010628) IEA: GO_REF:107
regulation of metabolic process (GO:0019222) IEA: OMA_Fun:001
regulation of cell migration (GO:0030334) IEA: GO_REF:107
establishment or maintenance of microtubule cytoskeleton polarity (GO:0030951) IEA: GO_REF:107
regulation of cellular metabolic process (GO:0031323) IEA: OMA_Fun:001
regulation of organelle organization (GO:0033043) IEA: OMA_Fun:001
protein localization to nucleus (GO:0034504) IEA: GO_REF:107
cellular protein localization (GO:0034613) IEA: OMA_Fun:001
sterol regulatory element binding protein import into nucleus (GO:0035105) IEA: GO_REF:107
negative regulation of cellular process (GO:0048523) IEA: OMA_Fun:001
regulation of cellular process (GO:0050794) IEA: OMA_Fun:001
regulation of nitrogen compound metabolic process (GO:0051171) IEA: OMA_Fun:001
ventricular cardiac muscle cell development (GO:0055015) IEA: GO_REF:107
cellular response to hypoxia (GO:0071456) IEA: GO_REF:107
negative regulation of mesenchymal cell proliferation (GO:0072201) IEA: GO_REF:107
negative regulation of release of cytochrome c from mitochondria (GO:0090201) IEA: GO_REF:107
positive regulation of cell aging (GO:0090343) IEA: GO_REF:107
regulation of protein localization to nucleus (GO:1900180) IEA: GO_REF:107
negative regulation of cardiac muscle hypertrophy in response to stress (GO:1903243) IEA: GO_REF:107
negative regulation of extrinsic apoptotic signaling pathway (GO:2001237) IEA: GO_REF:107

Protein Sequence

KPGWRATTGC PAPCPASPFR PLCITRLQEK EDLQELNDRL AVYIDRVRSL ETENAGLRLR    60
ITESEEVVSR EVSGIKAAYE AELGDARKTL DSVAKERARL QLELSKVREE FKELKARNTK   120
KEGDLMAAQA RLKDLEALLN SKEAALSTAL SEKRTLEGEL HDLRGQVAKL EAALGEAKKQ   180
LQDEMLRRVD AENRLQTLKE ELDFQKNIYS EELRETKRRH ETRLVEIDNG KQREFESRLA   240
DALQELRAQH EDQVEQYKKE LEKTYSAKLD NARQSAERNS NLVGAAHEEL QQSRIRIDSL   300
SAQLSQLQKQ LAAKEAKLRD LEDSLARGPS VPLARLRLSP SPTSQRSRGR ASSHSSQTQG   360
SGSVTKKRKL EAAESRSSFS QHARTSGRVA VEEVDEEGKF VRLRNKSSED QSMGNWQIKR   420
QNGDDPLLTY RFPPKFTLKA GQVVTIWAAG AGATHSPPSD LVWKAQNTWG CGNSLRTALI   480
NSTGEEVAMR KLVRSVTVVE DDEDEDGDDL LHHHHGSHCS SSGDPAEYNL RSRTVLCGTC   540
GQPADKASAS GSGAQVGGTI SSGSSASSVT VTRSYRSVGG SGGSGFGDSL VTRSYLLGNS   600
SPRTQSPQNC SIM                                                      613