Entry PONAB03194 (H2NK76)

EPongo abelii


General information

Description
G protein-coupled receptor 18 [Source:HGNC Symbol;Acc:4472]
Organism
PONAB - Pongo abelii
Locus
Chromosome 13: complement(101592947..101593942)
Protein Structures
pmp logo Protein Model Portal: H2NK76

IDs and Cross-references

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
signal transducer activity (GO:0004871) IEA: GO_REF:038
G-protein coupled receptor activity (GO:0004930) IEA: GO_REF:002, GO_REF:038

Cellular component
GO termEvidence and reference
integral component of plasma membrane (GO:0005887) IEA: OMA_Fun:001
membrane (GO:0016020) IEA: GO_REF:038
integral component of membrane (GO:0016021) IEA: GO_REF:002, GO_REF:038
cytoplasmic vesicle membrane (GO:0030659) IEA: OMA_Fun:001

Biological process
GO termEvidence and reference
CD8-positive, alpha-beta intraepithelial T cell differentiation (GO:0002300) IEA: GO_REF:107
CD8-positive, gamma-delta intraepithelial T cell differentiation (GO:0002305) IEA: GO_REF:107
negative regulation of leukocyte chemotaxis (GO:0002689) IEA: GO_REF:107
signal transduction (GO:0007165) IEA: GO_REF:038
G-protein coupled receptor signaling pathway (GO:0007186) IEA: GO_REF:002, GO_REF:038
T cell differentiation (GO:0030217) IEA: OMA_Fun:001
negative regulation of tumor necrosis factor production (GO:0032720) IEA: GO_REF:107
positive regulation of Rho protein signal transduction (GO:0035025) IEA: OMA_Fun:001
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway (GO:0051482) IEA: OMA_Fun:001

Protein Sequence

MITLNTQDQP VPFNSSHPDE YKIAALVFYS CIFIIGLFVN VTALWVFSCT TKKRTTVTIY    60
MMNVALVDLI FIMTLPFRMF YYAKDEWPFG EYFCQILGAL TVFYPSIALW LLAFISADRY   120
MAIVQPKYAK ELKNTCKAVL ACVGVWIMTL TTTIPLLLLY KDPDKDSTPA TCLKISDIIY   180
LKAVNVLNLT RLTFFFLIPL FIMIGCYLVI IHNLLHGRTS KLKPKVKEKS IRIIITLLVQ   240
VLVCFMPFHI CFAFLMLGTG ENSYNPWGAF TTFLMNLSTC LDVILYYIVS KQFQARVISV   300
MLYRNYLRSM RRKSFRSGSL RSLSNINSEM L                                  331