Entry ICTTR11688 ()

EIctidomys tridecemlineatus


General information

Description
vacuolar protein sorting 35 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:13487]
Organism
ICTTR - Ictidomys tridecemlineatus
Locus
JH393285.1: join(complement(72062..72163), complement(70100..70196), complement(69077..69200), (more...)

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
protein transporter activity (GO:0008565) IEA: OMA_Fun:001
D1 dopamine receptor binding (GO:0031748) IEA: OMA_Fun:001

Cellular component
GO termEvidence and reference
lysosome (GO:0005764) IEA: OMA_Fun:001
early endosome (GO:0005769) IEA: OMA_Fun:001
late endosome (GO:0005770) IEA: OMA_Fun:001
vacuolar membrane (GO:0005774) IEA: OMA_Fun:001
cytosol (GO:0005829) IEA: OMA_Fun:001
endosome membrane (GO:0010008) IEA: OMA_Fun:001
integral component of membrane (GO:0016021) IEA: OMA_Fun:001
retromer, cargo-selective complex (GO:0030906) IEA: OMA_Fun:001
neuron projection (GO:0043005) IEA: OMA_Fun:001
neuronal cell body (GO:0043025) IEA: OMA_Fun:001
tubular endosome (GO:0097422) IEA: OMA_Fun:001
mitochondrion-derived vesicle (GO:0099073) IEA: OMA_Fun:001

Biological process
GO termEvidence and reference
positive regulation of gene expression (GO:0010628) IEA: OMA_Fun:001
regulation of protein stability (GO:0031647) IEA: OMA_Fun:001
protein localization to organelle (GO:0033365) IEA: OMA_Fun:001
retrograde transport, endosome to Golgi (GO:0042147) IEA: OMA_Fun:001
mitochondrial fragmentation involved in apoptotic process (GO:0043653) IEA: OMA_Fun:001
transcytosis (GO:0045056) IEA: OMA_Fun:001
negative regulation of inflammatory response (GO:0050728) IEA: OMA_Fun:001
positive regulation of dopamine receptor signaling pathway (GO:0060161) IEA: OMA_Fun:001
positive regulation of Wnt protein secretion (GO:0061357) IEA: OMA_Fun:001
positive regulation of mitochondrial fission (GO:0090141) IEA: OMA_Fun:001
mitochondrion to lysosome transport (GO:0099074) IEA: OMA_Fun:001
neurotransmitter receptor transport, endosome to plasma membrane (GO:0099639) IEA: OMA_Fun:001
negative regulation of neuron death (GO:1901215) IEA: OMA_Fun:001
negative regulation of late endosome to lysosome transport (GO:1902823) IEA: OMA_Fun:001
regulation of dendritic spine maintenance (GO:1902950) IEA: OMA_Fun:001
positive regulation of cellular protein catabolic process (GO:1903364) IEA: OMA_Fun:001
regulation of cellular protein localization (GO:1903827) IEA: OMA_Fun:001
regulation of terminal button organization (GO:2000331) IEA: OMA_Fun:001

Protein Sequence

QPTTQQSPQD EQEKLLDEAI QAVKVQSFQM KRCLDKNKLM DALKHASNML GELRTSMLSP    60
KSYYELYMAI SDELHYLEVY LTDEFAKGRK VADLYELVQY AGNIIPRLYL LITVGVVYVK   120
SFPQSRKDIL KDLVEMCRGV QHPLRGLFLR NYLLQCTRNI LPDEGEPTDE ETTGDISDSM   180
DFVLLNFAEM NKLWVRMQHQ GHSRDREKRE RERQELRILV GTNLVRLSQL EGVNVERYKQ   240
IVLTGILEQV VNCRDALAQE YLMECIIQVF PDEFHLQTLN PFLRACAELH QNVNVKNIII   300
ALIDRLALFA HREDGPGIPA DIKLFDIFSQ QVATVIQSRQ DMPSEDVVSL QVSLINLAMK   360
CYPDRVDYVD KVLETTVEIF NKLNLEHIAT SSAVSKELTR LLKIPVDTYN NILTVLKLKH   420
FHPLFEYFDY ESRKSMSCYV LSNVLDYNTE IVSQDQVDSI MNLVSTLIQD QPDQPIEDPD   480
PEDFADEQSL VGRFIHLLRS EDPDQQYLIL NTARKHFGAG GNQRIRFTLP PLVFAAYQLA   540
FRYKENSKVD DKWEKKCQKI FSFAHQTISA LIKAELAELP LRLFLQGALA AGEIGFENHE   600
TVAYEFMSQA FSLYEDEISD SKAQLAAITL IIGTFERMKC FSEENHEPLR TQCALAASKL   660
LKKPDQGRAV STCAHLFWSG RNTDKNGEEL HGGKRVMECL KKALKIANQC MDPSLQVQLF   720
IEILNRYIYF YEKENDAVTI QVLNQLIQKI REDLPNLESS EETEQINKHF HNTLEHLRLR   780
RESPESEGPI YEGLIL                                                   796