Entry RATNO07317 (Q641X0)

ERattus norvegicus


General information

Description
sterile alpha motif domain containing 8 [Source:RGD Symbol;Acc:1306447]
Organism
RATNO - Rattus norvegicus
Locus
Chromosome 15: join(complement(2730848..2731021), complement(2705844..2706436), (more...)
Protein Structures
pmp logo Protein Model Portal: Q641X0

IDs and Cross-references

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
ceramide phosphoethanolamine synthase activity (GO:0002950) ISO: PMID:25605874, PMID:25667419
IEA: GO_REF:107
sphingomyelin synthase activity (GO:0033188) IBA: GO_REF:033
ceramide cholinephosphotransferase activity (GO:0047493) IBA: GO_REF:033

Cellular component
GO termEvidence and reference
endoplasmic reticulum (GO:0005783) IEA: GO_REF:107
cytosol (GO:0005829) IEA: GO_REF:107
integral component of plasma membrane (GO:0005887) IBA: GO_REF:033
membrane (GO:0016020) IEA: GO_REF:038
integral component of membrane (GO:0016021) IEA: GO_REF:038
integral component of Golgi membrane (GO:0030173) IBA: GO_REF:033
integral component of endoplasmic reticulum membrane (GO:0030176) ISO: PMID:19506037
IBA: GO_REF:033
IEA: GO_REF:107

Biological process
GO termEvidence and reference
ceramide biosynthetic process (GO:0046513) ISO: PMID:19506037, PMID:25605874, PMID:25667419
IBA: GO_REF:033
IEA: GO_REF:107
ceramide phosphoethanolamine biosynthetic process (GO:1905373) ISO: PMID:25667419
IEA: GO_REF:107
regulation of ceramide biosynthetic process (GO:2000303) ISO: PMID:19506037
IEA: GO_REF:107

Protein Sequence

MPARSRAGSR QRSGSLPRPS RLPLEALSSA YAPRTPDSDG AIDTGSELGP GSPAPTAEEV    60
EEEMAGPSQL CIRRWTPRHV AVWLKEEGFF EYVDILCNKH RLDGVTLLTL TEYDLRSPPL   120
EIKVLGDIKR LMLSVRKLQK THIDVLEEMG YNSDSPISPM TPFISALQSA DWLCNGEPAH   180
SCDGPIPDLS SDQYQYMNGK NKHCARRLDP EYWKTVLSCV YVFIVFGFTS FIMVIVHERV   240
PDMQTYPPLP DIFLDSVPRI PWAFSMTEVC GMILCYIWIL VLLLHKHRSI LLRRLCSLMG   300
TVFLLRCFTM FVTSLSVPGQ HLQCTGKVYG SVWEKLHRAF AIWSGFGMTL TGVHTCGDYM   360
FSGHTVVLTM LNFFVTEYTP RSWNFLHTLS WVLNLFGIFF ILAAHEHYSI DVFIAFYITT   420
RLFLYYHTLA NTRAYHQSRR ARIWFPMFSF FECNVNGTVP NEYCWPFSKP AIMKRLIG     478