Entry MOUSE08396 (A0A0A0MQD5)

EMus musculus


General information

Description
SH3/ankyrin domain gene 3 [Source:MGI Symbol;Acc:MGI:1930016]
Organism
MOUSE - Mus musculus
Locus
Chromosome 15: join(89499632..89499919, 89500215..89500418, 89501404..89501475, 89503120..89503228, (more...)
Alternative splicing
MOUSE08397
Protein Structures
pmp logo Protein Model Portal: A0A0A0MQD5

IDs and Cross-references

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
protein C-terminus binding (GO:0008022) IEA: GO_REF:107
ionotropic glutamate receptor binding (GO:0035255) IEA: GO_REF:107
scaffold protein binding (GO:0097110) IEA: GO_REF:107

Cellular component
GO termEvidence and reference
intracellular (GO:0005622) IEA: GO_REF:108
plasma membrane (GO:0005886) IEA: GO_REF:107
neuron projection (GO:0043005) IEA: GO_REF:107
neuron spine (GO:0044309) IEA: GO_REF:107

Biological process
GO termEvidence and reference
MAPK cascade (GO:0000165) IEA: GO_REF:107
embryonic epithelial tube formation (GO:0001838) IEA: GO_REF:107
synapse assembly (GO:0007416) IEA: GO_REF:107
learning or memory (GO:0007611) IEA: GO_REF:107
learning (GO:0007612) IEA: GO_REF:107
memory (GO:0007613) IEA: GO_REF:107
locomotory behavior (GO:0007626) IEA: GO_REF:107
striatal medium spiny neuron differentiation (GO:0021773) IEA: GO_REF:107
negative regulation of actin filament bundle assembly (GO:0032232) IEA: GO_REF:107
social behavior (GO:0035176) IEA: GO_REF:107
exploration behavior (GO:0035640) IEA: GO_REF:107
locomotory exploration behavior (GO:0035641) IEA: GO_REF:107
locomotion (GO:0040011) IEA: GO_REF:107
negative regulation of cell volume (GO:0045794) IEA: GO_REF:107
regulation of synaptic plasticity (GO:0048167) IEA: GO_REF:107
positive regulation of long-term neuronal synaptic plasticity (GO:0048170) IEA: GO_REF:107
brain morphogenesis (GO:0048854) IEA: GO_REF:107
neuromuscular process controlling balance (GO:0050885) IEA: GO_REF:107
positive regulation of synapse structural plasticity (GO:0051835) IEA: GO_REF:107
positive regulation of synaptic transmission, glutamatergic (GO:0051968) IEA: GO_REF:107
long-term synaptic potentiation (GO:0060291) IEA: GO_REF:107
long term synaptic depression (GO:0060292) IEA: GO_REF:107
dendritic spine morphogenesis (GO:0060997) IEA: GO_REF:107
positive regulation of dendritic spine development (GO:0060999) IEA: GO_REF:107
regulation of dendritic spine morphogenesis (GO:0061001) IEA: GO_REF:107
vocalization behavior (GO:0071625) IEA: GO_REF:107
postsynaptic density assembly (GO:0097107) IEA: GO_REF:107
AMPA glutamate receptor clustering (GO:0097113) IEA: GO_REF:107
NMDA glutamate receptor clustering (GO:0097114) IEA: GO_REF:107
guanylate kinase-associated protein clustering (GO:0097117) IEA: GO_REF:107
regulation of long-term synaptic potentiation (GO:1900271) IEA: GO_REF:107
positive regulation of long-term synaptic potentiation (GO:1900273) IEA: GO_REF:107
positive regulation of glutamate receptor signaling pathway (GO:1900451) IEA: GO_REF:107
regulation of long term synaptic depression (GO:1900452) IEA: GO_REF:107
regulation of AMPA glutamate receptor clustering (GO:1904717) IEA: GO_REF:107
positive regulation of excitatory postsynaptic potential (GO:2000463) IEA: GO_REF:107
regulation of grooming behavior (GO:2000821) IEA: GO_REF:107
regulation of behavioral fear response (GO:2000822) IEA: GO_REF:107
positive regulation of AMPA receptor activity (GO:2000969) IEA: GO_REF:107

Protein Sequence

MQLNRAAVAA AAAPAEPPEP LSPALAPAPA PPGPLPRSAV GGALAGGQGG PGRRAESPCA    60
PLSAGNSPGP GASTGMDGPG ASAVVVRVGI PDLQQTKCLR LDPTAPVWAA KQRVLCALNH   120
SLQDALNYGL FQPPSRGRAG KFLDEERLLQ DYPPNLDTPL PYLEFRYKRR VYAQNLIDDK   180
QFAKLHTKAN LKKFMDYVQL HSTDKVARLL DKGLDPNFHD PDSGECPLSL AAQLDNATDL   240
LKVLRNGGAH LDFRTRDGLT AVHCATRQRN AGALTTLLDL GASPDYKDSR GLTPLYHSAL   300
GGGDALCCEL LLHDHAQLGT TDENGWQEIH QACRFGHVQH LEHLLFYGAN MGAQNASGNT   360
ALHICALYNQ ESCARVLLFR GANKDVRNYN SQTAFQVAII AGNFELAEVI KTHKDSDVVP   420
FRETPSYAKR RRLAGPSGLA SPRPLQRSAS DINLKGDQPA ASPGPTLRSL PHQLLLQRLQ   480
EEKDRDRDGE LENDISGPSA GRGGHNKISP SGPGGSGPAP GPGPASPAPP APPPRGPKRK   540
LYSAVPGRKF IAVKAHSPQG EGEIPLHRGE AVKVLSIGEG GFWEGTVKGR TGWFPADCVE   600
EVQMRQYDTR HETREDRTKR LFRHYTVGSY DSLTSHSDYV IDDKVAILQK RDHEGFGFVL   660
RGAKAETPIE EFTPTPAFPA LQYLESVDVE GVAWRAGLRT GDFLIEVNGV NVVKVGHKQV   720
VGLIRQGGNR LVMKVVSVTR KPEEDGARRR APPPPKRAPS TTLTLRSKSM TAELEELASI   780
RRRKGEKLDE ILAVAAEPTL RPDIADADSR AATVKQRPTS RRITPAEISS LFERQGLPGP   840
EKLPGSLRKG IPRTKSVGED EKLASLLEGR FPRSTSMQDT VREGRGIPPP PQTAPPPPPA   900
PYYFDSGPPP TFSPPPPPGR AYDTVRSSFK PGLEARLGAG AAGLYDPSTP LGPLPYPERQ   960
KRARSMIILQ DSAPEVGDVP RPAPAATPPE RPKRRPRPSG PDSPYANLGA FSASLFAPSK  1020
PQRRKSPLVK QLQVEDAQER AALAVGSPGP VGGSFAREPS PTHRGPRPGS LDYSSGEGLG  1080
LTFGGPSPGP VKERRLEERR RSTVFLSVGA IEGSPPSADL PSLQPSRSID ERLLGTGATT  1140
GRDLLLPSPV SALKPLVGGP SLGPSGSTFI HPLTGKPLDP SSPLALALAA RERALASQTP  1200
SRSPTPVHSP DADRPGPLFV DVQTRDSERG PLASPAFSPR SPAWIPVPAR REAEKPPREE  1260
RKSPEDKKSM ILSVLDTSLQ RPAGLIVVHA TSNGQEPSRL GAEEERPGTP ELAPAPMQAA  1320
AVAEPMPSPR AQPPGSIPAD PGPGQGSSEE EPELVFAVNL PPAQLSSSDE ETREELARIG  1380
LVPPPEEFAN GILLTTPPPG PGPLPTTVPS PASGKPSSEL PPAPESAADS GVEEADTRSS  1440
SDPHLETTST ISTVSSMSTL SSESGELTDT HTSFADGHTF LLEKPPVPPK PKLKSPLGKG  1500
PVTFRDPLLK QSSDSELMAQ QHHAASTGLA SAAGPARPRY LFQRRSKLWG DPVESRGLPG  1560
PEDDKPTVIS ELSSRLQQLN KDTRSLGEEP VGGLGSLLDP AKKSPIAAAR LFSSLGELST  1620
ISAQRSPGGP GGGASYSVRP SGRYPVARRA PSPVKPASLE RVEGLGAGVG GAGRPFGLTP  1680
PTILKSSSLS IPHEPKEVRF VVRSVSARSR SPSPSPLPSP SPGSGPSAGP RRPFQQKPLQ  1740
LWSKFDVGDW LESIHLGEHR DRFEDHEIEG AHLPALTKED FVELGVTRVG HRMNIERALR  1800
QLDGS                                                              1805