Entry HUMAN08411 (DDHD1_HUMAN)

EHomo sapiens


General information

Description
DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]
Organism
HUMAN - Homo sapiens
Locus
Chromosome 14: join(complement(53152261..53153098), complement(53103683..53103856), (more...)

IDs and Cross-references

UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot DDHD1_HUMAN (Acc.: Q8NEL9)
Ensembl
Ensembl ENSG00000100523.14, Ensembl ENSP00000327104.5, Ensembl ENST00000323669.9
Refseq
Refseq logo NP_001153620(Acc.:Refseq logo NP_001153620.1)
EntrezGene
Entrez logo 80821
HGNC
DDHD1 DDHD domain containing 1
NCBI
ncbi logo AAH18014, ncbi logo AAH30703, ncbi logo BAB21796, ncbi logo BAB71679, ncbi logo EAW80623

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
phospholipase activity (GO:0004620) IBA: GO_REF:033
hydrolase activity (GO:0016787) IEA: GO_REF:037
metal ion binding (GO:0046872) IEA: GO_REF:002

Cellular component
GO termEvidence and reference
cytoplasm (GO:0005737) IBA: GO_REF:033
IEA: GO_REF:037, GO_REF:039

Biological process
GO termEvidence and reference
lipid metabolic process (GO:0006629) IEA: GO_REF:037
lipid catabolic process (GO:0016042) IEA: GO_REF:037
positive regulation of mitochondrial fission (GO:0090141) IDA: PMID:24599962

Protein Sequence

MNYPGRGSPR SPEHNGRGGG GGAWELGSDA RPAFGGGVCC FEHLPGGDPD DGDVPLALLR    60
GEPGLHLAPG TDDHNHHLAL DPCLSDENYD FSSAESGSSL RYYSEGESGG GGSSLSLHPP   120
QQPPLVPTNS GGGGATGGSP GERKRTRLGG PAARHRYEVV TELGPEEVRW FYKEDKKTWK   180
PFIGYDSLRI ELAFRTLLQT TGARPQGGDR DGDHVCSPTG PASSSGEDDD EDRACGFCQS   240
TTGHEPEMVE LVNIEPVCVR GGLYEVDVTQ GECYPVYWNQ ADKIPVMRGQ WFIDGTWQPL   300
EEEESNLIEQ EHLNCFRGQQ MQENFDIEVS KSIDGKDAVH SFKLSRNHVD WHSVDEVYLY   360
SDATTSKIAR TVTQKLGFSK ASSSGTRLHR GYVEEATLED KPSQTTHIVF VVHGIGQKMD   420
QGRIIKNTAM MREAARKIEE RHFSNHATHV EFLPVEWRSK LTLDGDTVDS ITPDKVRGLR   480
DMLNSSAMDI MYYTSPLYRD ELVKGLQQEL NRLYSLFCSR NPDFEEKGGK VSIVSHSLGC   540
VITYDIMTGW NPVRLYEQLL QKEEELPDER WMSYEERHLL DELYITKRRL KEIEERLHGL   600
KASSMTQTPA LKFKVENFFC MGSPLAVFLA LRGIRPGNTG SQDHILPREI CNRLLNIFHP   660
TDPVAYRLEP LILKHYSNIS PVQIHWYNTS NPLPYEHMKP SFLNPAKEPT SVSENEGIST   720
IPSPVTSPVL SRRHYGESIT NIGKASILGA ASIGKGLGGM LFSRFGRSST TQSSETSKDS   780
MEDEKKPVAS PSATTVGTQT LPHSSSGFLD SAYFRLQESF FNLPQLLFPE NVMQNKDNAL   840
VELDHRIDFE LREGLVESRY WSAVTSHTAY WSSLDVALFL LTFMYKHEHD DDAKPNLDPI   900