List of all proteins in the group
Allows comparison of IDs and descriptions
of all proteins in the OMA Group.
Display an MSA of all sequences in the group.
The MSA is created using the Mafft program.
The jalview applet allows for numerous
display and export options.
Display closely related groups
The close groups are made of the set of all
groups that are linked by at least one pair
of orthologs.
Note that not all pairs of proteins coming
from close groups are orthologous. If that
were the case, the two groups would have
been merged.
Display phyletic profile
The "Phyletic profile" displays OMA groups
that have similar patterns of presence/absence
across species. This can be useful to detect
proteins that have complementary function
(e.g. member of the same metabolic pathway).
Compare GO annotations
This function displays a table of all
Gene Ontology (GO) annotations on
proteins of the OMA group. This
allows to compare the annotations
and serves as an additional description
of this OMA group.
OMA fingerprint
The fingerprint is a subsequence that is specific to a
certain group in the current OMA release
Since the group number is specific to a release, this
is the best way to track a group across releases.
OMA

Keyword Protein Sequence Group Entry

OMA Group 240784

defender against cell death 1
This group has 64 members: 64 [E]ukaryota
Fingerprint: HLVVINF

Protein List | Alignment | Close Groups | Phyletic Profile | Ontology Download: download fasta, download darwin

[E] Homo sapiensHUMAN10075  UniProtKB/Swiss-Prot DAD1_HUMAN   -
[E] Pan troglodytesPANTR12356  Ensembl ENSPTRP00000010410   -
[E] Pongo pygmaeus abeliiPONAB04470  Ensembl ENSPPYP00000006408  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (EC 2.4.1.119) (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1).
[E] Macaca mulattaMACMU12982  Ensembl ENSMMUP00000001123   -
[E] Ochotona princepsOCHPR03133  Ensembl ENSOPRP00000000865   -
[E] Cavia porcellusCAVPO05504  Ensembl ENSCPOP00000000763  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1)(EC 2.4.1.119)(Defender against cell death 1)(DAD-1) [Source:UniProtKB/Swiss- Prot;Acc:P61803]
[E] Dipodomys ordiiDIPOR03398  Ensembl ENSDORP00000007667  defender against cell death 1 Gene [Source:MGI Symbol;Acc:MGI:101912]
[E] Mus musculusMOUSE11680  UniProtKB/Swiss-Prot DAD1_MOUSE  defender against cell death 1
[E] Rattus norvegicusRATNO08498  UniProtKB/Swiss-Prot DAD1_RAT  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (EC 2.4.1.119) (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1). [Source:UniProtKB/Swiss- Prot;Acc:P61805]
[E] Procavia capensisPROCA15730  Ensembl ENSPCAP00000015125  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1)(EC 2.4.1.119)(Defender against cell death 1)(DAD-1) [Source:UniProtKB/Swiss- Prot;Acc:P61803]
[E] Loxodonta africanaLOXAF01431  Ensembl ENSLAFP00000000560   -
[E] Echinops telfairiECHTE14529  Ensembl ENSETEP00000005117   -
[E] Canis familiarisCANFA07542  Ensembl ENSCAFP00000016393   -
[E] Felis catusFELCA09651  Ensembl ENSFCAP00000002801   -
[E] Tursiops truncatusTURTR07505  Ensembl ENSTTRP00000013767   -
[E] Bos taurusBOVIN16939  UniProtKB/Swiss-Prot DAD1_BOVIN  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (EC 2.4.1.119) (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1)
[E] Lama guanicoe pacosLAMPA02946  Ensembl ENSVPAP00000004954  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1)(EC 2.4.1.119)(Defender against cell death 1)(DAD-1) [Source:UniProtKB/Swiss- Prot;Acc:P61803]
[E] Pteropus vampyrusPTEVA16855  Ensembl ENSPVAP00000009691   -
[E] Erinaceus europaeusERIEU05478  Ensembl ENSEEUP00000007419   -
[E] Sorex araneusSORAR02487  Ensembl ENSSARP00000001466   -
[E] Equus caballusHORSE07258  Ensembl ENSECAP00000000357  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (EC 2.4.1.119) (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1).
[E] Dasypus novemcinctusDASNO02658  Ensembl ENSDNOP00000008967   -
[E] Choloepus hoffmanniCHOHO03176  Ensembl ENSCHOP00000004204  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1)(EC 2.4.1.119)(Defender against cell death 1)(DAD-1) [Source:UniProtKB/Swiss- Prot;Acc:P61803]
[E] Monodelphis domesticaMONDO00584  Ensembl ENSMODP00000006958  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (EC 2.4.1.119) (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1).
[E] Macropus eugeniiMACEU07611  Ensembl ENSMEUP00000004743  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1)(EC 2.4.1.119)(Defender against cell death 1)(DAD-1) [Source:UniProtKB/Swiss- Prot;Acc:P61803]
[E] Gallus gallusCHICK07334  Ensembl ENSGALP00000040147   -
[E] Taeniopygia guttataTAEGU08675  UniProtKB/TrEMBL B5FXK7   -
[E] Anolis carolinensisANOCA05558  Ensembl ENSACAP00000002965  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1)(EC 2.4.1.119)(Defender against cell death 1)(DAD-1) [Source:UniProtKB/Swiss- Prot;Acc:P61803]
[E] Xenopus tropicalisXENTR14096  UniProtKB/TrEMBL Q28FI0   -
[E] Oryzias latipesORYLA05817  Ensembl ENSORLP00000015636   -
[E] Gasterosteus aculeatusGASAC02618  Ensembl ENSGACP00000019058   -
[E] Takifugu rubripesFUGRU03560  Ensembl ENSTRUP00000001256  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (EC 2.4.1.119) (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1)
[E] Tetraodon nigroviridisTETNG12225  UniProtKB/TrEMBL Q4SNQ2  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1)(EC 2.4.1.119)(Defender against cell death 1)(DAD-1) [Source:UniProtKB/Swiss- Prot;Acc:P61803]
[E] Danio rerioDANRE08434  UniProtKB/TrEMBL A7E2L0   -
[E] Branchiostoma floridaeBRAFL23544  UniProtKB/TrEMBL C3YFB2  jgi|Brafl1|217231|e_gw.69.194.1
[E] Ciona intestinalisCIOIN05807  Ensembl ENSCINP00000023292   -
[E] Ciona savignyiCIOSA00773  Ensembl ENSCSAVP00000019375   -
[E] Helobdella robustaHELRO00625   155584  jgi|Helro1|155584
[E] Lottia giganteaLOTGI17391   193969  jgi|Lotgi1|193969|estExt_Genewise1.C_sca_560109
[E] Ixodes scapularisIXOSC03773  UniProtKB/TrEMBL B7P488  defender against cell death
[E] Daphnia pulexDAPPU08423   PASA_GEN_1100136  jgi|Dappu1|300829|PASA_GEN_1100136
[E] Drosophila melanogasterDROME01061  UniProtKB/Swiss-Prot DAD1_DROME  Defender against cell death 1 (DAD-1).
[E] Drosophila pseudoobscuraDROPS08861  UniProtKB/TrEMBL Q29NZ4  
[E] Anopheles gambiaeANOGA09202  UniProtKB/TrEMBL Q7Q4M9  Defender against programmed cell death.
[E] Aedes aegyptiAEDAE10752  UniProtKB/TrEMBL Q1HRQ3   -
[E] Pristionchus pacificusPRIPA09597   WBGene00099244  locus:Ppa-dad-1; status:Partially_confirmed
[E] Caenorhabditis brenneriCAEBI04016   WBGene00142967  locus:Cbn-dad-1
[E] Caenorhabditis briggsaeCAEBR12447  UniProtKB/TrEMBL A8XGA0  
[E] Caenorhabditis elegansCAEEL01175  UniProtKB/Swiss-Prot DAD1_CAEEL  dad-1 encodes an ortholog of human DAD1 (OMIM:600243) that inhibits cell death and can functionally complement the hamster protein in cultured cells.
[E] Caenorhabditis japonicaCAEJA02234   WBGene00121501  locus:Cjp-dad-1; status:Confirmed
[E] Caenorhabditis remaneiCAERE27257   WBGene00066722  locus:Cre-dad-1
[E] Nematostella vectensisNEMVE14953  UniProtKB/TrEMBL A7SMZ2  jgi|Nemve1|191508|estExt_GenewiseH_1.C_2090019
[E] Dictyostelium discoideumDICDI11145  UniProtKB/Swiss-Prot DAD1_DICDI  
[E] Phaeosphaeria nodorumPHANO12669  UniProtKB/TrEMBL Q0UVF4  hypothetical protein
[E] Pichia stipitisPICST03539  UniProtKB/TrEMBL A3LU86  oligosaccharyltransferase epsilon subunit
[E] Saccharomyces cerevisiaeYEAST01492  UniProtKB/Swiss-Prot OST2_YEAST  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase epsilon subunit
[E] Schizosaccharomyces pombeSCHPO01173  UniProtKB/Swiss-Prot OST2_SCHPO  oligosaccharyltransferase (epsilon subunit) (predicted); defender against cell death homolog; similar to S. cerevisiae OST2
[E] Laccaria bicolorLACBI11566   eu2.Lbscf0004g09760  jgi|Lacbi1|312020|eu2.Lbscf0004g09760
[E] Candida glabrataCANGA00388  UniProtKB/TrEMBL Q6FXM9  similar to uniprot|P46964 Saccharomyces cerevisiae YOR103c OST2 oligosaccharyltransferase epsilon subunit;
[E] Oryza sativaORYSA10796   BAF14578.1  Defender against cell death 1 (DAD-1) (Defender against apoptotic death 1 protein) contains InterPro domain(s): IPR003038 identical to O50070 supported by AK063198
[E] Sorghum bicolorSORBI00553  UniProtKB/TrEMBL C5Z2Q5  jgi|Sorbi1|130311|fgenesh1_pm.C_chr_10000016
[E] Populus trichocarpaPOPTR29146  UniProtKB/TrEMBL A9PAU8  jgi|Poptr1_1|712040|estExt_Genewise1_v1.C_LG_III1005 [DNA did not match protein] [DNA partly invalid]
[E] Arabidopsis thalianaARATH03015  UniProtKB/Swiss-Prot DAD1_ARATH  defender against cell death 1 (DAD1), identical to defender against cell death 1 (DAD-1, AtDAD1) (Arabidopsis thaliana) SWISS-PROT:Q39080; go_component: membrane [goid GO:0003674@[ND]; GO:0005783@[IDA]; GO:0006916@[IGI]; GO:0016020@[ISS]] [evidence ISS] [pmid 9225471]; go_function: molecular function unknown [goid GO:0005554] [evidence ND]; go_process: anti-apoptosis [goid GO:0006916] [evidence IGI] [pmid 9225471] ATDAD1 (DEFENDER AGAINST APOPTOTIC DEATH 1)
[E] Vitis viniferaVITVI10949  UniProtKB/TrEMBL A7PC19