| [B] Nocardia farcinica | NOCFA05029 | Q5YPL6 | putative dihydrofolate reductase |
| [B] Rhodococcus sp. (strain RHA1) | RHOSR02201 | Q0SEI0 | Dihydrofolate reductase |
| [B] Bifidobacterium longum | BIFLO01578 | C5EBA9 | Dihydrofolate reductase |
| [B] Bifidobacterium longum (strain DJO10A) | BIFLD01768 | B3DQJ7 | Dihydrofolate reductase |
| [B] Bacteroides thetaiotaomicron | BACTN02030 | Q8A638 | Dihydrofolate reductase |
| [B] Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152) | PARD803623 | A6LIC1 | Putative dihydrofolate reductase |
| [B] Lactobacillus salivarius subsp. salivarius (strain UCC118) | LACS100690 | Q1WU16 | Dihydrofolate reductase COG0262 [H] Dihydrofolate reductase |
| [B] Bartonella bacilliformis (strain ATCC 35685 / KC583) | BARBK00838 | A1UTA4 | Dihydrofolate reductase |
| [B] Bartonella henselae | BARHE01038 | Q6G2S9 | Dihydrofolate reductase |
| [B] Bartonella quintana | BARQU00831 | Q6FZ92 | Dihydrofolate reductase |
| [B] Bartonella tribocorum (strain CIP 105476 / IBS 506) | BART101249 | A9IW81 | Dihydrofolate reductase type III (EC 1.5.1.3)(P11045) ,InterPro; Dihydrofolate reductase hypothetical protein |
| [B] Rhodopseudomonas palustris | RHOPA03479 | Q6N448 | dihydrofolate reductase |
| [B] Rhodopseudomonas palustris (strain BisB18) | RHOPB03206 | Q211Y1 | Dihydrofolate reductase |
| [B] Rhodopseudomonas palustris (strain TIE-1) | RHOPT03936 | B3QEZ8 | Dihydrofolate reductase |
| [B] Methylobacterium sp. (strain 4-46) | METS401023 | B0UDD2 | Dihydrofolate reductase |
| [B] Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) | PARL102380 | A7HVX5 | Dihydrofolate reductase |
| [B] Rhizobium etli (strain CFN 42 / ATCC 51251) | RHIEC02730 | Q2K6G9 | dihydrofolate reductase protein similar to folA (SMc01442) [Sinorhizobium meliloti] and BMEI0609 [Brucella melitensis] Similar to swissprot:Q92NQ7 Putative location:bacterial cytoplasm Psort-Score: 0.0994; go_function: oxidoreductase activity [goid 0016491]; go_function: dihydrofolate reductase activity [goid 0004146]; go_process: nucleotide biosynthesis [goid 0009165]; go_process: glycine biosynthesis [goid 0006545] |
| [B] Rhizobium etli (strain CIAT 652) | RHIE602898 | B3PTQ3 | Dihydrofolate reductase protein |
| [B] Rhizobium leguminosarum bv. trifolii (strain WSM2304) | RHILW02504 | B5ZWE4 | Dihydrofolate reductase |
| [B] Rhizobium leguminosarum bv. viciae (strain 3841) | RHIL303245 | Q1ME83 | putative dihydrofolate reductase similarity:fasta; with=UniProt:DYR_ECOLI (EMBL:AE016755); Shigella flexneri.; folA; Dihydrofolate reductase (EC 1.5.1.3).; length=159; id 40.244; 164 aa overlap; query 7-170; subject 3-159 similarity:fasta; with=UniProt:Q8UDS4_AGRT5 (EMBL:AE008121); Agrobacterium tumefaciens (strain C58/ATCC 33970).; folA; Dihydrofolate reductase (AGR_C_3708p).; length=175; id 53.179; 173 aa overlap; query 1-172; subject 1-173 |
| [B] Hyphomonas neptunium (strain ATCC 15444) | HYPNA00459 | Q0C500 | Dihydrofolate reductase |
| [B] Maricaulis maris (strain MCS10) | MARMM02019 | Q0AN20 | Dihydrofolate reductase |
| [B] Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) | MAGMM01312 | BAE50130.1 | Dihydrofolate reductase |
| [B] Rhodospirillum centenum (strain ATCC 51521 / SW) | RHOCS01925 | B6INW3 | Dihydrofolate reductase |
| [B] Novosphingobium aromaticivorans (strain DSM 12444) | NOVAD03235 | Q2G376 | Dihydrofolate reductase |
| [B] Sphingopyxis alaskensis | SPHAL02332 | Q1GQK3 | Dihydrofolate reductase |
| [B] Delftia acidovorans (strain DSM 14801 / SPH-1) | DELAS04879 | A9BMQ5 | Dihydrofolate reductase |
| [B] Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) | NEIG101493 | Q5F669 | Best Blastp Hit: sp|P04174|DYR_NEIGO dihydrofolate reductase >gi|66103|pir||RDNHD dihydrofolate reductase (EC 1.5.1.3) - Neisseria gonorrhoeae COG0262 Dihydrofolate reductase; FolA dihydrofolate reductase |
| [B] Neisseria gonorrhoeae (strain NCCP11945) | NEIG202008 | B4RNR3 | FolA |
| [B] Neisseria meningitidis serogroup A | NEIMA01923 | DYR_NEIMA | Dihydrofolate reductase |
| [B] Neisseria meningitidis serogroup B | NEIMB00285 | DYR_NEIMB | Dihydrofolate reductase |
| [B] Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / FAM18) | NEIMF01678 | A1KVY2 | Dihydrofolate reductase |
| [B] Aeromonas salmonicida (strain A449) | AERS400835 | A4SJJ4 | Dihydrofolate reductase |
| [B] Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) | SACD200351 | Q21NW4 | Dihydrofolate reductase |
| [B] Pseudoalteromonas atlantica (strain T6c / BAA-1087) | PSEA603694 | Q15PF1 | Dihydrofolate reductase |
| [B] Halorhodospira halophila (strain DSM 244 / SL1) | HALHL02015 | A1WYQ0 | Dihydrofolate reductase |
| [B] Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) | CITK803224 | A8ALQ3 | Putative uncharacterized protein |
| [B] Enterobacter sakazakii (strain ATCC BAA-894) | ENTS803198 | A7MIB4 | Putative uncharacterized protein |
| [B] Escherichia coli (strain 55989 / EAEC) | ECO5500046 | B7L4H1 | Dihydrofolate reductase |
| [B] Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) | ECOLC03506 | B1IRC8 | Dihydrofolate reductase |
| [B] Escherichia coli (strain DH10B) | ECODH00044 | B1XC49 | Dihydrofolate reductase |
| [B] Escherichia coli (strain K12) | ECOLI00044 | DYR_ECOLI | Dihydrofolate reductase |
| [B] Escherichia coli (strain SE11) | ECOSE00049 | B6HZ29 | Dihydrofolate reductase |
| [B] Escherichia coli (strain SMS-3-5 / SECEC) | ECOSM00050 | B1LFY2 | Dihydrofolate reductase |
| [B] Escherichia coli (strain UTI89 / UPEC) | ECOUT00054 | Q1RGF0 | dihydrofolate reductase |
| [B] Escherichia coli O127:H6 (strain E2348/69 / EPEC) | ECO2700047 | B7UI94 | Dihydrofolate reductase |
| [B] Escherichia coli O139:H28 (strain E24377A / ETEC) | ECO2400050 | A7ZHE1 | Dihydrofolate reductase |
| [B] Escherichia coli O157:H7 | ECO5700051 | Q8XA18 | Residues 1 to 159 of 159 are 99.37 pct identical to residues 1 to 159 of 159 from Escherichia coli K-12 Strain MG1655: B0048 dihydrofolate reductase type I; trimethoprim resistance |
| [B] Escherichia coli O157:H7 (strain EC4115 / EHEC) | ECO5E00048 | B5YZ84 | Dihydrofolate reductase |
| [B] Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) | ECOLU00048 | B7N7S3 | Dihydrofolate reductase |
| [B] Escherichia coli O1:K1 / APEC | ECOK100043 | A1A797 | dihydrofolate reductase |
| [B] Escherichia coli O45:K1 (strain S88 / ExPEC) | ECO4500049 | B7MAH1 | Dihydrofolate reductase |
| [B] Escherichia coli O6 | ECOL600056 | DYR_ECOL6 | Dihydrofolate reductase |
| [B] Escherichia coli O6:K15:H31 (strain 536) | ECOL500048 | Q0TLU1 | dihydrofolate reductase |
| [B] Escherichia coli O7:K1 (strain IAI39 / ExPEC) | ECO7I00049 | B7NHF2 | Dihydrofolate reductase |
| [B] Escherichia coli O81 (strain ED1a) | ECO8100046 | B7MNQ5 | Dihydrofolate reductase |
| [B] Escherichia coli O9:H4 (strain HS) | ECOHS00051 | A7ZW00 | Dihydrofolate reductase |
| [B] Photorhabdus luminescens (subsp. laumondii) | PHOLL00591 | Q7N8W0 | dihydrofolate reductase |
| [B] Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) | SALAR02800 | A9MQG5 | Putative uncharacterized protein |
| [B] Salmonella agona (strain SL483) | SALA400092 | B5F768 | Dihydrofolate reductase |
| [B] Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 | SALCH00081 | Q57TH3 | IPR001796: Dihydrofolate reductase dihydrofolate reductase type I; trimethoprim resistance |
| [B] Salmonella dublin (strain CT_02021853) | SALDC00083 | B5FI31 | Dihydrofolate reductase |
| [B] Salmonella enteritidis PT4 (strain P125109) | SALEP00084 | B5R1S5 | Dihydrofolate reductase type I |
| [B] Salmonella gallinarum (strain 287/91 / NCTC 13346) | SALG200084 | B5RGB9 | Dihydrofolate reductase type I |
| [B] Salmonella heidelberg (strain SL476) | SALHS00085 | B4TJ44 | Dihydrofolate reductase |
| [B] Salmonella newport (strain SL254) | SALNS00089 | B4T6L3 | Dihydrofolate reductase |
| [B] Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) | SALPB00111 | A9MYM1 | Putative uncharacterized protein |
| [B] Salmonella paratyphi A (strain AKU_12601) | SALPK00087 | B5BL24 | Dihydrofolate reductase type I |
| [B] Salmonella paratyphi-a | SALPA00080 | Q5PDE2 | similar to Salmonella typhi CT18 dihydrofolate reductase type I dihydrofolate reductase type I |
| [B] Salmonella schwarzengrund (strain CVM19633) | SALSV00095 | B4TWT3 | Dihydrofolate reductase |
| [B] Salmonella typhi | SALTI00089 | Q8Z9J9 | Dihydrofolate reductase type I |
| [B] Salmonella typhimurium | SALTY00085 | C9X680 | similar to Escherichia coli dihydrofolate reductase type I; trimethoprim resistance (AAC73159.1) dihydrofolate reductase type I |
| [B] Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) | SHIB300034 | B2U256 | Dihydrofolate reductase |
| [B] Shigella boydii serotype 4 (strain Sb227) | SHIBS00034 | Q326I5 | trimethoprim resistance; Code: H; COG: COG0262 dihydrofolate reductase type I |
| [B] Shigella dysenteriae serotype 1 (strain Sd197) | SHIDS00061 | Q32K48 | trimethoprim resistance; Code: H; COG: COG0262 dihydrofolate reductase type I |
| [B] Shigella flexneri | SHIFL00044 | NP_706004.1 | Residues 1 to 140 of 140 are 100 pct identical to residues 20 to 159 of a 159 aa protein from Escherichia coli K12 ref: NP_414590.1 dihydrofolate reductase type I; trimethoprim resistance |
| [B] Shigella flexneri serotype 5b (strain 8401) | SHIF800039 | Q0T8E7 | dihydrofolate reductase type I Code: H; COG: COG0262 |
| [B] Shigella sonnei (strain Ss046) | SHISS00046 | Q3Z5W1 | trimethoprim resistance; Code: H; COG: COG0262 dihydrofolate reductase type I |
| [B] Sodalis glossinidius (strain morsitans) | SODGM00414 | Q2NVX9 | dihydrofolate reductase |
| [B] Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) | YERE800587 | A1JJF1 | Dihydrofolate reductase |
| [B] Yersinia pestis | YERPE00456 | A6BV19 | Dihydrofolate reductase |
| [B] Yersinia pestis (biovar Antiqua strain Antiqua) | YERPA03851 | Q1C0I2 | Dihydrofolate reductase |
| [B] Yersinia pestis (biovar Antiqua strain Nepal516) | YERPN00344 | Q1CMT9 | Dihydrofolate reductase |
| [B] Yersinia pestis (strain Pestoides F) | YERPP02971 | A4TQE3 | Dihydrofolate reductase |
| [B] Yersinia pestis bv. Antiqua (strain Angola) | YERPG00660 | A9QZZ6 | Dihydrofolate reductase |
| [B] Yersinia pseudotuberculosis | YERPS00623 | Q66ER3 | Dihydrofolate reductase type I; trimethoprim resistance |
| [B] Yersinia pseudotuberculosis (serotype O:1b / strain IP 31758) | YERP303380 | A7FMC6 | Dihydrofolate reductase |
| [B] Yersinia pseudotuberculosis serotype IB (strain PB1/+) | YERPB00629 | B2K483 | Dihydrofolate reductase region |
| [B] Yersinia pseudotuberculosis serotype O:3 (strain YPIII) | YERPY03508 | B1JKY8 | Dihydrofolate reductase |
| [B] Methylococcus capsulatus | METCA02560 | Q603S1 | identified by similarity to SP:P11045; match to protein family HMM PF00186 dihydrofolate reductase |
| [B] Actinobacillus succinogenes (strain ATCC 55618 / 130Z) | ACTSZ00703 | A6VM90 | Dihydrofolate reductase |
| [B] Pseudomonas aeruginosa | PSEAE00350 | A3LHF9 | Dihydrofolate reductase |
| [B] Pseudomonas aeruginosa (strain LESB58) | PSEA800346 | B7V2R3 | Dihydrofolate reductase |
| [B] Pseudomonas aeruginosa (strain UCBPP-PA14) | PSEAB00364 | Q02U65 | dihydrofolate reductase |
| [B] Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) | PSEF505787 | Q4K492 | identified by match to protein family HMM PF00186 dihydrofolate reductase |
| [B] Pseudomonas putida (strain F1 / ATCC 700007) | PSEP104941 | A5WAG5 | Dihydrofolate reductase |
| [B] Pseudomonas putida (strain GB-1) | PSEPG05137 | B0KN86 | Dihydrofolate reductase unknown EC_number=1.5.1.3 PFAM: dihydrofolate reductase region KEGG: pen:PSEEN0273 dihydrofolate reductase type I, trimethoprim resistance |
| [B] Pseudomonas putida (strain KT2440) | PSEPK05022 | Q88CP8 | identified by match to PFAM protein family HMM PF00186 dihydrofolate reductase |
| [B] Xanthomonas axonopodis (pv. citri) | XANAC00831 | Q8PP44 | identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark dihydrofolate reductase type III |
| [B] Ruthia magnifica subsp. Calyptogena magnifica | RUTMC00920 | A1AXR7 | Dihydrofolate reductase |