| [B] Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP) | ACIFD01821 | C7M1S8 | DNA topoisomerase I |
| [B] Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1) | CORA700220 | C3PJV8 | DNA topoisomerase |
| [B] Corynebacterium diphtheriae | CORDI00316 | Q6NJR6 | DNA topoisomerase |
| [B] Corynebacterium efficiens | COREF00304 | C8NKH1 | similar to AL035636-5|CAB38480.1| percent identity: 57 in 988 aa putative DNA topoisomerase I |
| [B] Corynebacterium glutamicum | CORGL00308 | Q8NTJ8 | DNA topoisomerase |
| [B] Corynebacterium glutamicum (strain R) | CORGB00398 | A4QAW2 | Hypothetical protein |
| [B] Corynebacterium jeikeium (strain K411) | CORJK01880 | Q4JSS2 | DNA topoisomerase I |
| [B] Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717) | CORK401897 | C4LLJ1 | DNA topoisomerase |
| [B] Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) | CORU701837 | B1VI08 | DNA topoisomerase I |
| [B] Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) | MYCA900484 | B1MGQ4 | DNA topoisomerase |
| [B] Mycobacterium avium (strain 104) | MYCA100490 | A0QA61 | DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051 |
| [B] Mycobacterium paratuberculosis | MYCPA00420 | Q744B6 | DNA topoisomerase |
| [B] Mycobacterium gilvum (strain PYR-GCK) | MYCGI01323 | A4T5R5 | DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Mycobacterium leprae | MYCLE00197 | TOP1_MYCLE | DNA topoisomerase 1 |
| [B] Mycobacterium leprae (strain Br4923) | MYCLB00197 | B8ZU27 | Putative DNA topoisomerase I |
| [B] Mycobacterium marinum (strain ATCC BAA-535 / M) | MYCMM05037 | B2HJ79 | DNA topoisomerase I TopA |
| [B] Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | MYCS205835 | A0R5D9 | DNA topoisomerase I |
| [B] Mycobacterium sp. (strain JLS) | MYCSJ05089 | A3Q719 | DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Mycobacterium sp. (strain KMS) | MYCSK04786 | A1UML4 | DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Mycobacterium sp. (strain MCS) | MYCSS04755 | Q1B2I4 | DNA topoisomerase I |
| [B] Mycobacterium bovis | MYCBO03657 | TOP1_MYCBO | Mb3670c, topA, len: 934 aa. Equivalent to Rv3646c, len: 934 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 934 aa overlap). topA, DNA topoisomerase I (EC 5.99.1.2) (see citation below), equivalent to O69548|TOP1_MYCLE|TOPA|ML0200|MLCB2548.31c DNA TOPOISOMERASE I from Mycobacterium leprae (947 aa) FASTA scores: opt: 5150, E(): 0, (84.6% identity in 936 aa overlap). Also highly similar to many e.g. Q9X909|TOP1_STRCO|TOPA|SCH5.06c from Streptomyces coelicolor (952 aa), FASTA scores: opt: 2754, E(): 1.3e-153, (61.3% identity in 928 aa overlap); P73810|TOP1_SYNY3|TOPA|SLR2058 from Synechocystis sp. strain PCC 6803 (898 aa), FASTA scores: opt: 1442, E(): 9.1e-77, (47.15% identity in 927 aa overlap); P47368|TOP1_MYCGE|TOPA|MG122 from Mycoplasma genitalium (709 aa), FASTA scores: opt: 865, E(): 4.8e-43, (30.3% identity in 736 aa overlap); P06612|TOP1_ECOLI|TOPA|SUPX|B1274 from Escherichia coli strain K12 (865 aa), FASTA scores: opt: 397, E(): 0, (39.6% identity in 704 aa overlap); etc. BELONGS TO PROKARYOTIC TYPE I/III TOPOISOMERASE FAMILY. DNA TOPOISOMERASE I TOPA (OMEGA-PROTEIN) (RELAXING ENZYME) (UNTWISTING ENZYME) (SWIVELASE) (TYPE I DNA TOPOISOMERASE) (NICKING-CLOSING ENZYME) |
| [B] Mycobacterium bovis (strain BCG / Paris 1173P2) | MYCBP03645 | A1KPX5 | DNA topoisomerase I topA |
| [B] Mycobacterium tuberculosis | MYCTU03671 | TOP1_MYCTU | DNA topoisomerase 1 |
| [B] Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) | MYCTA03709 | A5U8X0 | DNA topoisomerase I topA |
| [B] Mycobacterium tuberculosis (strain F11) | MYCTF03578 | A5WTL1 | DNA topoisomerase I topA (omega-protein) Mapped to H37Rv Rv3646c |
| [B] Mycobacterium ulcerans (strain Agy99) | MYCUA03436 | A0PV84 | DNA topoisomerase I TopA Detected in the cytoplasmic fraction by 2D-LC- MS/MS. cytoplasmic protein the reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. [catalytic activity: ATP-independent breakage of single-stranded DNA, followed by passage and rejoining] |
| [B] Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) | MYCVP05239 | A1TG67 | DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Nocardia farcinica | NOCFA00370 | Q5Z2Y2 | DNA topoisomerase |
| [B] Rhodococcus erythropolis (strain PR4 / NBRC 100887) | RHOE400511 | C0ZNG9 | DNA topoisomerase I |
| [B] Rhodococcus opacus (strain B4) | RHOOB04260 | C1BA07 | DNA topoisomerase I |
| [B] Rhodococcus sp. (strain RHA1) | RHOSR04278 | Q0S8J3 | DNA topoisomerase I |
| [B] Frankia alni (strain ACN14a) | FRAAA06419 | Q0RBI4 | DNA topoisomerase I (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Evidence 2b : Function of strongly homologous gene; Product type e : enzyme |
| [B] Frankia sp. (strain CcI3) | FRASC04180 | Q2J4Z1 | DNA topoisomerase |
| [B] Frankia sp. (strain EAN1pec) | FRASN00304 | A8LF30 | DNA topoisomerase I precursor |
| [B] Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) | KINRD00485 | A6W588 | DNA topoisomerase |
| [B] Tropheryma whipplei (strain TW08/27) | TROW800678 | Q83HB7 | Similar to Escherichia coli DNA topoisomerase I TopA or SupX or b1274 SWALL:TOP1_ECOLI (SWALL:P06612) (865 aa) fasta scores: E(): 3e-47, 36.55% id in 766 aa, and to Bifidobacterium longum NCC2705 DNA topoisomerase i topA SWALL:AAN24314 (EMBL:AE014668) (1030 aa) fasta scores: E(): 2.9e-49, 45.38% id in 932 aa DNA topoisomerase I |
| [B] Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860) | BRAFD02493 | C7MGF4 | DNA topoisomerase I |
| [B] Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) | JONDD02139 | C7R1J9 | DNA topoisomerase I |
| [B] Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) | CLAMS00178 | B0RAE2 | Probable DNA topoisomerase I |
| [B] Leifsonia xyli subsp. xyli | LEIXX00295 | Q6AGT6 | DNA topoisomerase |
| [B] Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) | ARTCA03105 | B8HFR7 | DNA topoisomerase I |
| [B] Arthrobacter sp. (strain FB24) | ARTS203324 | A0K0B0 | DNA topoisomerase I KEGG: sco:SCO3543 probable DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Kocuria rhizophila (strain ATCC 9341 / NBRC 12708 / DC2201) | KOCRD00469 | B2GH68 | DNA topoisomerase I |
| [B] Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / IFO 15589) | RENSM02630 | A9WTD8 | DNA topoisomerase I |
| [B] Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74) | SANKS03184 | D1BDU2 | DNA topoisomerase I |
| [B] Tropheryma whipplei (strain Twist) | TROWT00693 | Q83FM2 | DNA topoisomerase |
| [B] Salinispora arenicola (strain CNS-205) | SALAI04179 | A8M5X0 | DNA topoisomerase I |
| [B] Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) | SALTO03959 | A4XC00 | DNA topoisomerase I |
| [B] Nocardioides sp. (strain BAA-499 / JS614) | NOCSJ00370 | A1SDN6 | DNA topoisomerase I |
| [B] Propionibacterium acnes | PROAC00237 | Q6AB64 | DNA topoisomerase |
| [B] Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) | SACVD03442 | C7MQK9 | DNA topoisomerase |
| [B] Phytoplasma sp. (strain STRAWB1) | STRAW04619 | Q82EJ4 | DNA topoisomerase |
| [B] Streptomyces coelicolor | STRCO03516 | TOP1_STRCO | SCH5.06c, probable DNA topoisomerase I, len: 952 aa; high levels of similarity to many e.g. SW:TOP1_MYCTU DNA topoisomerase I from Mycobacterium tuberculosis (900 aa) fasta scores; opt: 2586, z-score: 2586.7, E(): 0, (58.6% identity in 846 aa overlap). Contains PS00396 Prokaryotic DNA topoisomerase I active site and Pfam match to entry PF01131 Topoisom_bac, Prokayotic DNA topoisomerase, score 736.60, E-value 1.1e-217. Also contains alanine/lysine rich C-terminal region. probable DNA topoisomerase I |
| [B] Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) | STRGG03174 | B1VM20 | Putative DNA topoisomerase I |
| [B] Streptomyces scabies (strain 87.22) | STRSW03883 | C9Z2D8 | DNA topoisomerase I |
| [B] Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083) | BIFAA00159 | A0ZZQ9 | DNA topoisomerase I Catalyzes the ATP-dependent breakage ofsignle-stranded DNA followed by passage and rejoining_maintains net negative superhelicity Orthologue of Rv3646c_BL0485 |
| [B] Bifidobacterium animalis subsp. lactis (strain AD011) | BIFA000204 | B8DVL2 | DNA topoisomerase |
| [B] Bifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219) | BIFLB00216 | C6A666 | DNA topoisomerase |
| [B] Bifidobacterium longum | BIFLO01117 | Q8G6Z5 | DNA topoisomerase |
| [B] Bifidobacterium longum (strain DJO10A) | BIFLD01258 | B3DUA2 | Topoisomerase I |
| [B] Bacteroides fragilis | BACFR04392 | Q64MY0 | DNA topoisomerase |
| [B] Bacteroides fragilis (strain ATCC 25285 / NCTC 9343) | BACFN04103 | Q5L7R0 | Similar to Zymomonas mobilis DNA topoisomerase I TopA SWALL:TOP1_ZYMMO (SWALL:Q9X3X7) (1217 aa) fasta scores: E(): 1.3e-73, 39.36% id in 663 aa, and to Bacteroides thetaiotaomicron DNA topoisomerase I BT2827 SWALL:Q8A3X7 (EMBL:AE016937) (782 aa) fasta scores: E(): 0, 82.35% id in 782 aa, and to Porphyromonas gingivalis W83 DNA topoisomerase I TopA or PG0754 SWALL:AAQ65921 (EMBL:AE017174) (788 aa) fasta scores: E(): 3.5e-169, 59.82% id in 779 aa putative DNA topoisomerase I |
| [B] Bacteroides thetaiotaomicron | BACTN02794 | Q8A3X7 | DNA topoisomerase |
| [B] Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) | BACV801235 | A6L010 | DNA topoisomerase I |
| [B] Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152) | PARD803485 | A6LHY3 | DNA topoisomerase I |
| [B] Porphyromonas gingivalis | PORGI00646 | Q7MW85 | DNA topoisomerase |
| [B] Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) | PORG300741 | B2RIV5 | DNA topoisomerase I |
| [B] Amoebophilus asiaticus (strain 5a2) | AMOA500991 | B3ETD4 | Putative uncharacterized protein |
| [B] Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / VPI 2845) | CAPOD00330 | C7M620 | DNA topoisomerase I |
| [B] Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511) | FLAPJ01918 | A6H115 | DNA topoisomerase I |
| [B] Gramella forsetii (strain KT0803) | GRAFK02941 | A0M5R7 | DNA topoisomerase I |
| [B] Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) | CHIPD01939 | C7PC68 | DNA topoisomerase |
| [B] Salinibacter ruber (strain DSM 13855) | SALRD01077 | Q2S3I6 | DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051 |
| [B] Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) | CYTH302301 | Q11SL3 | DNA topoisomerase type I (omega protein) |
| [B] Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) | DYAFD01179 | C6W599 | DNA topoisomerase |
| [B] Acaryochloris marina (strain MBIC 11017) | ACAM101906 | B0CFN9 | DNA topoisomerase I |
| [B] Cyanothece sp. (strain PCC 8802) | CYAP000832 | C7QKW5 | DNA topoisomerase I |
| [B] Microcystis aeruginosa (strain NIES-843) | MICAN05310 | B0JHS3 | DNA topoisomerase |
| [B] Synechococcus sp. (strain CC9605) | SYNSC00586 | Q3AM11 | DNA topoisomerase I |
| [B] Synechococcus sp. (strain CC9902) | SYNS901747 | Q3AWJ8 | DNA topoisomerase I |
| [B] Synechococcus sp. (strain JA-2-3B'a(2-13)) | SYNJB02259 | Q2JJ84 | DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051 |
| [B] Synechococcus sp. (strain JA-3-3Ab) | SYNJA00529 | Q2JWS9 | DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051 |
| [B] Synechococcus sp. (strain PCC 6301) | SYNP600138 | Q5N5T9 | DNA topoisomerase I |
| [B] Synechococcus sp. (strain RCC307) | SYNR300659 | A5GRQ4 | DNA topoisomerase I |
| [B] Synechococcus sp. (strain WH7803) | SYNPW01880 | A5GMZ4 | DNA topoisomerase I |
| [B] Synechococcus sp. (strain WH8102) | SYNPX01871 | Q7U539 | DNA topoisomerase |
| [B] Synechocystis sp. (strain PCC 6803) | SYNY301276 | TOP1_SYNY3 | DNA topoisomerase 1 |
| [B] Thermosynechococcus elongatus (strain BP-1) | THEEB01852 | Q8DHR4 | DNA topoisomerase I |
| [B] Anabaena variabilis (strain ATCC 29413 / PCC 7937) | ANAVT00030 | Q3MH80 | DNA topoisomerase I |
| [B] Anabaena sp. (strain PCC 7120) | ANASP02748 | Q8YTE2 | DNA topoisomerase |
| [B] Nostoc punctiforme (strain ATCC 29133 / PCC 73102) | NOSP704047 | B2IWS5 | DNA topoisomerase I |
| [B] Trichodesmium erythraeum (strain IMS101) | TRIEI00019 | Q11AC4 | DNA topoisomerase I |
| [B] Prochlorococcus marinus | PROMA00432 | Q7VDE6 | DNA topoisomerase |
| [B] Prochlorococcus marinus (strain MIT 9211) | PROM400433 | A9BE54 | DNA topoisomerase |
| [B] Prochlorococcus marinus (strain MIT 9215) | PROM200513 | A8G3F0 | DNA topoisomerase I |
| [B] Prochlorococcus marinus (strain MIT 9301) | PROM000461 | A3PBF8 | Prokaryotic DNA topoisomerase COG550 Topoisomerase IA [DNA replication, recombination, and repair] |
| [B] Prochlorococcus marinus (strain MIT 9303) | PROM300621 | A2C7C2 | Prokaryotic DNA topoisomerase |
| [B] Prochlorococcus marinus (strain MIT 9312) | PROM900460 | Q31C99 | DNA topoisomerase I |
| [B] Prochlorococcus marinus (strain MIT 9313) | PROMM01346 | Q7V627 | Prokaryotic DNA topoisomerase |
| [B] Prochlorococcus marinus (strain MIT 9515) | PROM500498 | A2BV96 | Prokaryotic DNA topoisomerase COG550 Topoisomerase IA [DNA replication, recombination, and repair] |
| [B] Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) | PROMP00490 | Q7V2N7 | DNA topoisomerase |
| [B] Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) | DEIDV00800 | C1D174 | Putative DNA topoisomerase |
| [B] Deinococcus geothermalis (strain DSM 11300) | DEIGD01975 | Q1IWT9 | DNA topoisomerase I KEGG: dra:DR1374 DNA topoisomerase I, ev=0.0, 79% identity TIGRFAM: DNA topoisomerase I: (0) PFAM: TOPRIM: (5.6e-39) DNA topoisomerase, type IA, central: (4.8e-183) SMART: DNA topoisomerase, type IA, domain 2: (1.8e-50) DNA topoisomerase, type IA, DNA-binding: (2.8e-119) Toprim subdomain: (2e-39) |
| [B] Deinococcus radiodurans | DEIRA01344 | Q9RUL0 | DNA topoisomerase |
| [B] Rhodopirellula baltica | RHOBA04416 | Q7UMV5 | PMID: 8921893 best DB hits: BLAST: swissprot:Q9X909; TOP1_STRCO DNA TOPOISOMERASE I (OMEGA-PROTEIN); E=0.0 pir:G75403; DNA topoisomerase I - Deinococcus radiodurans (strain; E=0.0 swissprot:Q59567; TOP1_MYCTU DNA TOPOISOMERASE I (OMEGA-PROTEIN); E=0.0 COG: DR1374_1; COG0550 Topoisomerase IA; E=1e-170 PFAM: PF01751; Toprim domain; E=3.1e-39 PF01131; DNA topoisomerase; E=4e-164 DNA topoisomerase I |
| [B] Caulobacter crescentus | CAUCR02418 | Q9A5J6 | DNA topoisomerase |
| [B] Caulobacter crescentus (strain NA1000 / CB15N) | CAUCN02516 | B8GZL1 | DNA topoisomerase |
| [B] Caulobacter sp. (strain K31) | CAUSK01466 | B0T0I9 | DNA topoisomerase I |
| [B] Phenylobacterium zucineum (strain HLK1) | PHEZH01313 | B4R961 | DNA topoisomerase I |
| [B] Bartonella bacilliformis (strain ATCC 35685 / KC583) | BARBK00762 | A1UT28 | DNA topoisomerase I |
| [B] Bartonella henselae | BARHE00782 | Q6G3F7 | DNA topoisomerase I |
| [B] Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712) | BEII903305 | B2IEN4 | DNA topoisomerase I |
| [B] Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) | METSB03742 | B8EMQ0 | DNA topoisomerase I |
| [B] Bradyrhizobium japonicum | BRAJA05055 | Q89K08 | DNA topoisomerase |
| [B] Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) | BRASB04421 | A5EKR5 | DNA topoisomerase I |
| [B] Bradyrhizobium sp. (strain ORS278) | BRASO04260 | A4YWH0 | DNA topoisomerase I |
| [B] Nitrobacter hamburgensis (strain X14 / DSM 10229) | NITHX02293 | Q1QKM0 | DNA topoisomerase |
| [B] Rhodopseudomonas palustris | RHOPA03115 | Q6N559 | DNA topoisomerase |
| [B] Rhodopseudomonas palustris (strain BisA53) | RHOP503330 | Q07L73 | DNA topoisomerase I KEGG: rpc:RPC_2239 DNA topoisomerase TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Rhodopseudomonas palustris (strain BisB18) | RHOPB02201 | Q215Z3 | DNA topoisomerase |
| [B] Rhodopseudomonas palustris (strain BisB5) | RHOPS03013 | Q135I0 | DNA topoisomerase |
| [B] Rhodopseudomonas palustris (strain HaA2) | RHOP202410 | Q2IXD6 | DNA topoisomerase |
| [B] Rhodopseudomonas palustris (strain TIE-1) | RHOPT03470 | B3Q9Y2 | DNA topoisomerase I |
| [B] Brucella abortus | BRUAB02597 | Q578A3 | similar to BRA0604, DNA topoisomerase I TopA, DNA topoisomerase I |
| [B] Brucella abortus (strain 2308) | BRUA202805 | Q2YKM3 | DNA topoisomerase I:DNA topoisomerase I, ATP-binding:DNA topoisomerase I, DNA-binding:Bacterial DNA topoisomerase I:Toprim su... |
| [B] Brucella canis (strain ATCC 23365 / NCTC 10854) | BRUC202659 | A9MBP4 | DNA topoisomerase I |
| [B] Brucella melitensis | BRUME02709 | Q8YC66 | DNA TOPOISOMERASE I |
| [B] Brucella melitensis biotype 2 (strain ATCC 23457) | BRUMB02568 | C0RLC5 | DNA topoisomerase |
| [B] Brucella microti (strain CCM 4915) | BRUMC02689 | C7LI90 | DNA topoisomerase |
| [B] Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512) | BRUO202367 | A5VUT6 | DNA topoisomerase I |
| [B] Brucella suis | BRUSU02683 | D0PFV6 | identified by match to TIGR protein family HMM TIGR01054 DNA topoisomerase I |
| [B] Brucella suis (strain ATCC 23445 / NCTC 10510) | BRUSI02458 | A9WYS3 | DNA topoisomerase I GO_component: cytoplasm [GO ID 0005737]; GO_function: DNA binding [GO ID 0003677]; GO_process: DNA replication [GO ID 0006260] |
| [B] Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) | OCHA403621 | A6X573 | DNA topoisomerase |
| [B] Methylobacterium extorquens (strain PA1) | METEP03259 | A9W733 | DNA topoisomerase I |
| [B] Methylobacterium nodulans (strain ORS2060 / LMG 21967) | METNO03104 | B8IL44 | DNA topoisomerase I |
| [B] Methylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) | METPB03448 | B1ZKT9 | DNA topoisomerase I |
| [B] Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831) | METRJ00983 | B1M0P4 | DNA topoisomerase |
| [B] Methylobacterium sp. (strain 4-46) | METS404066 | B0UIR7 | DNA topoisomerase I |
| [B] Mesorhizobium sp. (strain BNC1) | MESSB01345 | Q11IM5 | DNA topoisomerase I KEGG: mlo:mlr0839 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain containing protein DNA topoisomerase, type IA, central DNA topoisomerase, type IA, zn finger SMART: DNA topoisomerase, type IA, domain 2 DNA topoisomerase, type IA, DNA-binding Toprim subdomain |
| [B] Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) | PARL102759 | A7HX05 | DNA topoisomerase |
| [B] Agrobacterium tumefaciens (strain C58 / ATCC 33970) | AGRT501276 | A9CJ93 | DNA topoisomerase |
| [B] Rhizobium etli (strain CIAT 652) | RHIE601687 | B3PW33 | DNA topoisomerase I protein |
| [B] Rhizobium meliloti | RHIME01286 | Q92QL9 | Product confidence : putative Gene name confidence : putative predicted by Codon_usage predicted by Homology predicted by FrameD PUTATIVE DNA TOPOISOMERASE I PROTEIN |
| [B] Sinorhizobium medicae (strain WSM419) | SINMW00923 | A6U807 | DNA topoisomerase |
| [B] Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) | AZOC501855 | A8I2E5 | DNA topoisomerase I |
| [B] Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) | XANP203817 | A7IM95 | DNA topoisomerase |
| [B] Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418) | HIRBI01970 | C6XL73 | DNA topoisomerase I |
| [B] Maricaulis maris (strain MCS10) | MARMM01278 | Q0AQ63 | DNA topoisomerase I |
| [B] Paracoccus denitrificans (strain Pd 1222) | PARDP00639 | A1AZS7 | DNA topoisomerase I KEGG: rsp:RSP_2178 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) | RHOS400760 | Q3J4F4 | Brings about the conversion of one topological isomer of DNA into another, e.g. the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of compleme Citation: Bensaid A, Almeida A, Drlica K, Rouviere-Yaniv J. J Mol Biol. 1996 Feb 23;256(2):292-300. PMID: 8594197 DNA topoisomerase I |
| [B] Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) | RHOS100824 | A3PHZ5 | DNA topoisomerase I KEGG: rsp:RSP_2178 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein |
| [B] Rhodobacter sphaeroides (strain KD131 / KCTC 12085) | RHOSK00474 | B9KNS1 | DNA topoisomerase I |
| [B] Roseobacter denitrificans (strain ATCC 33942 / OCh 114) | ROSDO01981 | Q167W6 | DNA topoisomerase I, putative |
| [B] Silicibacter pomeroyi | SILPO02999 | Q5LNX4 | identified by match to protein family HMM PF01131; match to protein family HMM PF01396; match to protein family HMM PF01751; match to protein family HMM TIGR01051 DNA topoisomerase I |
| [B] Silicibacter sp. (strain TM1040) | SILST02330 | Q1GE45 | DNA topoisomerase I KEGG: sil:SPO3079 DNA topoisomerase I, ev=0.0, 77% identity TIGRFAM: DNA topoisomerase I: (4.5e-272) PFAM: TOPRIM: (5.9e-29) DNA topoisomerase, type IA, central: (5.3e-138) DNA topoisomerase, type IA, zn finger: (3.4e-13) SMART: DNA topoisomerase, type IA, domain 2: (1.7e-46) DNA topoisomerase, type IA, DNA-binding: (2.5e-105) Toprim subdomain: (8.9e-30) |
| [B] Acetobacter pasteurianus (strain NBRC 3283 / LMG 1513 / CCTM 1153) | ACEP300719 | C7JES1 | DNA topoisomerase I |
| [B] Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) | GLUDA00039 | A9GZQ5 | DNA topoisomerase I |
| [B] Gluconobacter oxydans | GLUOX01212 | Q5FRH2 | DNA topoisomerase I |
| [B] Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) | GRABC00804 | Q0BU00 | DNA topoisomerase I |
| [B] Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) | MAGSA00678 | Q2W9I9 | DNA topoisomerase |
| [B] Rhodospirillum centenum (strain ATCC 51521 / SW) | RHOCS01476 | B6IN35 | DNA topoisomerase I |
| [B] Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) | RHORT03189 | Q2RPE8 | DNA topoisomerase |
| [B] Erythrobacter litoralis (strain HTCC2594) | ERYLH00956 | Q2NB87 | DNA topoisomeraseI COG0550 topoisomeraseIA |
| [B] Novosphingobium aromaticivorans (strain DSM 12444) | NOVAD01786 | Q2G7D0 | DNA topoisomerase |
| [B] Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) | SPHWW03778 | A5VD05 | DNA topoisomerase I |
| [B] Sphingopyxis alaskensis | SPHAL01196 | Q1GTU5 | DNA topoisomerase |
| [B] Thiobacillus denitrificans (strain ATCC 25259) | THIDA00010 | Q3SMS7 | DNA topoisomerase I |
| [B] Methylobacillus flagellatus (strain KT / ATTC 51484 / DSM 6875) | METFK00227 | Q1H4T9 | DNA topoisomerase |
| [B] Methylovorus sp. (strain SIP3-4) | METSD00244 | C6X8M3 | DNA topoisomerase I |
| [B] Arcobacter butzleri (strain RM4018) | ARCB402159 | A8EWX5 | DNA topoisomerase I |
| [B] Alkalilimnicola ehrlichei (strain MLHE-1) | ALHEH02610 | Q0A5B5 | DNA topoisomerase I |
| [B] Halorhodospira halophila (strain DSM 244 / SL1) | HALHL02292 | A1WZH7 | DNA topoisomerase I |
| [B] Thioalkalivibrio sp. (strain HL-EbGR7) | THISH00183 | B8GU07 | DNA topoisomerase |
| [B] Thiomicrospira crunogena (strain XCL-2) | THICR00195 | Q31J81 | DNA topoisomerase |
| [B] Stenotrophomonas maltophilia (strain K279a) | STRMK03928 | B2FIS0 | Putative DNA topoisomerase I |
| [B] Stenotrophomonas maltophilia (strain R551-3) | STRM503572 | B4SKI3 | DNA topoisomerase I |
| [B] Xanthomonas axonopodis pv. citri | XANAC03706 | Q8PG14 | DNA topoisomerase |
| [B] Xanthomonas campestris pv. campestris | XANCP03650 | Q8P4F3 | DNA topoisomerase |
| [B] Xanthomonas campestris pv. campestris (strain 8004) | XANC803717 | Q4UQ08 | DNA topoisomerase I |
| [B] Xanthomonas campestris pv. campestris (strain B100) | XANCB03920 | B0RWR4 | DNA topoisomerase I |
| [B] Xanthomonas campestris pv. vesicatoria (strain 85-10) | XANC503843 | Q3BNK0 | DNA topoisomerase I |
| [B] Xanthomonas oryzae (pv. oryzae) | XANOR00504 | Q5H5D7 | identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark DNA topoisomerase I |
| [B] Xanthomonas oryzae pv. oryzae (strain MAFF 311018) | XANOM00488 | Q2P832 | DNA topoisomerase I identified by sequence similarity; putative; ORF located using Blastx/Glimmer/GeneHacker |
| [B] Xanthomonas oryzae pv. oryzae (strain PXO99A) | XANOP00620 | B2SL47 | DNA topoisomerase I |
| [B] Xylella fastidiosa | XYLFA00889 | TOP1_XYLFA | DNA topoisomerase 1 |
| [B] Xylella fastidiosa (strain M12) | XYLFM01705 | B0U4M9 | DNA topoisomerase |
| [B] Xylella fastidiosa (strain M23) | XYLF201768 | B2I8S8 | DNA topoisomerase I |
| [B] Xylella fastidiosa (strain Temecula1 / ATCC 700964) | XYLFT01661 | TOP1_XYLFT | DNA topoisomerase 1 |
| [B] Ruthia magnifica subsp. Calyptogena magnifica | RUTMC00935 | A1AXT2 | DNA topoisomerase I |
| [B] Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) | VESOH00897 | A5CVH7 | DNA topoisomerase I |
| [B] Borrelia afzelii (strain PKo) | BORAP00838 | Q0SM23 | DNA topoisomerase I |
| [B] Borrelia burgdorferi | BORBU00827 | TOP1_BORBU | DNA topoisomerase 1 |
| [B] Borrelia burgdorferi (strain ZS7) | BORBZ00791 | B7J0S2 | DNA topoisomerase I |
| [B] Borrelia duttonii (strain Ly) | BORDL00798 | B5RN26 | DNA topoisomerase I |
| [B] Borrelia hermsii (strain DAH) | BORHD00802 | B2S1H2 | DNA topoisomerase I |
| [B] Borrelia recurrentis (strain A1) | BORRA00783 | B5RQG5 | DNA topoisomerase I |
| [B] Borrelia turicatae (strain 91E135) | BORT900800 | A1R0Q3 | DNA topoisomerase I |