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OMA

Keyword Protein Sequence Group Entry

OMA Group 208797

DNA topoisomerase
This group has 197 members: 197 [B]acteria
Fingerprint: KKVMPRL

Protein List | Alignment | Close Groups | Phyletic Profile | Ontology Download: download fasta, download darwin

[B] Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP)ACIFD01821  UniProtKB/TrEMBL C7M1S8  DNA topoisomerase I
[B] Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1)CORA700220  UniProtKB/TrEMBL C3PJV8  DNA topoisomerase
[B] Corynebacterium diphtheriaeCORDI00316  UniProtKB/TrEMBL Q6NJR6  DNA topoisomerase
[B] Corynebacterium efficiensCOREF00304  UniProtKB/TrEMBL C8NKH1  similar to AL035636-5|CAB38480.1| percent identity: 57 in 988 aa putative DNA topoisomerase I
[B] Corynebacterium glutamicumCORGL00308  UniProtKB/TrEMBL Q8NTJ8  DNA topoisomerase
[B] Corynebacterium glutamicum (strain R)CORGB00398  UniProtKB/TrEMBL A4QAW2  Hypothetical protein
[B] Corynebacterium jeikeium (strain K411)CORJK01880  UniProtKB/TrEMBL Q4JSS2  DNA topoisomerase I
[B] Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717)CORK401897  UniProtKB/TrEMBL C4LLJ1  DNA topoisomerase
[B] Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109)CORU701837  UniProtKB/TrEMBL B1VI08  DNA topoisomerase I
[B] Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)MYCA900484  UniProtKB/TrEMBL B1MGQ4  DNA topoisomerase
[B] Mycobacterium avium (strain 104)MYCA100490  UniProtKB/TrEMBL A0QA61  DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051
[B] Mycobacterium paratuberculosisMYCPA00420  UniProtKB/TrEMBL Q744B6  DNA topoisomerase
[B] Mycobacterium gilvum (strain PYR-GCK)MYCGI01323  UniProtKB/TrEMBL A4T5R5  DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Mycobacterium lepraeMYCLE00197  UniProtKB/Swiss-Prot TOP1_MYCLE  DNA topoisomerase 1
[B] Mycobacterium leprae (strain Br4923)MYCLB00197  UniProtKB/TrEMBL B8ZU27  Putative DNA topoisomerase I
[B] Mycobacterium marinum (strain ATCC BAA-535 / M)MYCMM05037  UniProtKB/TrEMBL B2HJ79  DNA topoisomerase I TopA
[B] Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)MYCS205835  UniProtKB/TrEMBL A0R5D9  DNA topoisomerase I
[B] Mycobacterium sp. (strain JLS)MYCSJ05089  UniProtKB/TrEMBL A3Q719  DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Mycobacterium sp. (strain KMS)MYCSK04786  UniProtKB/TrEMBL A1UML4  DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Mycobacterium sp. (strain MCS)MYCSS04755  UniProtKB/TrEMBL Q1B2I4  DNA topoisomerase I
[B] Mycobacterium bovisMYCBO03657  UniProtKB/Swiss-Prot TOP1_MYCBO  Mb3670c, topA, len: 934 aa. Equivalent to Rv3646c, len: 934 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 934 aa overlap). topA, DNA topoisomerase I (EC 5.99.1.2) (see citation below), equivalent to O69548|TOP1_MYCLE|TOPA|ML0200|MLCB2548.31c DNA TOPOISOMERASE I from Mycobacterium leprae (947 aa) FASTA scores: opt: 5150, E(): 0, (84.6% identity in 936 aa overlap). Also highly similar to many e.g. Q9X909|TOP1_STRCO|TOPA|SCH5.06c from Streptomyces coelicolor (952 aa), FASTA scores: opt: 2754, E(): 1.3e-153, (61.3% identity in 928 aa overlap); P73810|TOP1_SYNY3|TOPA|SLR2058 from Synechocystis sp. strain PCC 6803 (898 aa), FASTA scores: opt: 1442, E(): 9.1e-77, (47.15% identity in 927 aa overlap); P47368|TOP1_MYCGE|TOPA|MG122 from Mycoplasma genitalium (709 aa), FASTA scores: opt: 865, E(): 4.8e-43, (30.3% identity in 736 aa overlap); P06612|TOP1_ECOLI|TOPA|SUPX|B1274 from Escherichia coli strain K12 (865 aa), FASTA scores: opt: 397, E(): 0, (39.6% identity in 704 aa overlap); etc. BELONGS TO PROKARYOTIC TYPE I/III TOPOISOMERASE FAMILY. DNA TOPOISOMERASE I TOPA (OMEGA-PROTEIN) (RELAXING ENZYME) (UNTWISTING ENZYME) (SWIVELASE) (TYPE I DNA TOPOISOMERASE) (NICKING-CLOSING ENZYME)
[B] Mycobacterium bovis (strain BCG / Paris 1173P2)MYCBP03645  UniProtKB/TrEMBL A1KPX5  DNA topoisomerase I topA
[B] Mycobacterium tuberculosisMYCTU03671  UniProtKB/Swiss-Prot TOP1_MYCTU  DNA topoisomerase 1
[B] Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)MYCTA03709  UniProtKB/TrEMBL A5U8X0  DNA topoisomerase I topA
[B] Mycobacterium tuberculosis (strain F11)MYCTF03578  UniProtKB/TrEMBL A5WTL1  DNA topoisomerase I topA (omega-protein) Mapped to H37Rv Rv3646c
[B] Mycobacterium ulcerans (strain Agy99)MYCUA03436  UniProtKB/TrEMBL A0PV84  DNA topoisomerase I TopA Detected in the cytoplasmic fraction by 2D-LC- MS/MS. cytoplasmic protein the reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. [catalytic activity: ATP-independent breakage of single-stranded DNA, followed by passage and rejoining]
[B] Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)MYCVP05239  UniProtKB/TrEMBL A1TG67  DNA topoisomerase I KEGG: mmc:Mmcs_4796 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Nocardia farcinicaNOCFA00370  UniProtKB/TrEMBL Q5Z2Y2  DNA topoisomerase
[B] Rhodococcus erythropolis (strain PR4 / NBRC 100887)RHOE400511  UniProtKB/TrEMBL C0ZNG9  DNA topoisomerase I
[B] Rhodococcus opacus (strain B4)RHOOB04260  UniProtKB/TrEMBL C1BA07  DNA topoisomerase I
[B] Rhodococcus sp. (strain RHA1)RHOSR04278  UniProtKB/TrEMBL Q0S8J3  DNA topoisomerase I
[B] Frankia alni (strain ACN14a)FRAAA06419  UniProtKB/TrEMBL Q0RBI4  DNA topoisomerase I (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
[B] Frankia sp. (strain CcI3)FRASC04180  UniProtKB/TrEMBL Q2J4Z1  DNA topoisomerase
[B] Frankia sp. (strain EAN1pec)FRASN00304  UniProtKB/TrEMBL A8LF30  DNA topoisomerase I precursor
[B] Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)KINRD00485  UniProtKB/TrEMBL A6W588  DNA topoisomerase
[B] Tropheryma whipplei (strain TW08/27)TROW800678  UniProtKB/TrEMBL Q83HB7  Similar to Escherichia coli DNA topoisomerase I TopA or SupX or b1274 SWALL:TOP1_ECOLI (SWALL:P06612) (865 aa) fasta scores: E(): 3e-47, 36.55% id in 766 aa, and to Bifidobacterium longum NCC2705 DNA topoisomerase i topA SWALL:AAN24314 (EMBL:AE014668) (1030 aa) fasta scores: E(): 2.9e-49, 45.38% id in 932 aa DNA topoisomerase I
[B] Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860)BRAFD02493  UniProtKB/TrEMBL C7MGF4  DNA topoisomerase I
[B] Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134)JONDD02139  UniProtKB/TrEMBL C7R1J9  DNA topoisomerase I
[B] Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667)CLAMS00178  UniProtKB/TrEMBL B0RAE2  Probable DNA topoisomerase I
[B] Leifsonia xyli subsp. xyliLEIXX00295  UniProtKB/TrEMBL Q6AGT6  DNA topoisomerase
[B] Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)ARTCA03105  UniProtKB/TrEMBL B8HFR7  DNA topoisomerase I
[B] Arthrobacter sp. (strain FB24)ARTS203324  UniProtKB/TrEMBL A0K0B0  DNA topoisomerase I KEGG: sco:SCO3543 probable DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Kocuria rhizophila (strain ATCC 9341 / NBRC 12708 / DC2201)KOCRD00469  UniProtKB/TrEMBL B2GH68  DNA topoisomerase I
[B] Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / IFO 15589)RENSM02630  UniProtKB/TrEMBL A9WTD8  DNA topoisomerase I
[B] Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)SANKS03184  UniProtKB/TrEMBL D1BDU2  DNA topoisomerase I
[B] Tropheryma whipplei (strain Twist)TROWT00693  UniProtKB/TrEMBL Q83FM2  DNA topoisomerase
[B] Salinispora arenicola (strain CNS-205)SALAI04179  UniProtKB/TrEMBL A8M5X0  DNA topoisomerase I
[B] Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)SALTO03959  UniProtKB/TrEMBL A4XC00  DNA topoisomerase I
[B] Nocardioides sp. (strain BAA-499 / JS614)NOCSJ00370  UniProtKB/TrEMBL A1SDN6  DNA topoisomerase I
[B] Propionibacterium acnesPROAC00237  UniProtKB/TrEMBL Q6AB64  DNA topoisomerase
[B] Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)SACVD03442  UniProtKB/TrEMBL C7MQK9  DNA topoisomerase
[B] Phytoplasma sp. (strain STRAWB1)STRAW04619  UniProtKB/TrEMBL Q82EJ4  DNA topoisomerase
[B] Streptomyces coelicolorSTRCO03516  UniProtKB/Swiss-Prot TOP1_STRCO  SCH5.06c, probable DNA topoisomerase I, len: 952 aa; high levels of similarity to many e.g. SW:TOP1_MYCTU DNA topoisomerase I from Mycobacterium tuberculosis (900 aa) fasta scores; opt: 2586, z-score: 2586.7, E(): 0, (58.6% identity in 846 aa overlap). Contains PS00396 Prokaryotic DNA topoisomerase I active site and Pfam match to entry PF01131 Topoisom_bac, Prokayotic DNA topoisomerase, score 736.60, E-value 1.1e-217. Also contains alanine/lysine rich C-terminal region. probable DNA topoisomerase I
[B] Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)STRGG03174  UniProtKB/TrEMBL B1VM20  Putative DNA topoisomerase I
[B] Streptomyces scabies (strain 87.22)STRSW03883  UniProtKB/TrEMBL C9Z2D8  DNA topoisomerase I
[B] Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083)BIFAA00159  UniProtKB/TrEMBL A0ZZQ9  DNA topoisomerase I Catalyzes the ATP-dependent breakage ofsignle-stranded DNA followed by passage and rejoining_maintains net negative superhelicity Orthologue of Rv3646c_BL0485
[B] Bifidobacterium animalis subsp. lactis (strain AD011)BIFA000204  UniProtKB/TrEMBL B8DVL2  DNA topoisomerase
[B] Bifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219)BIFLB00216  UniProtKB/TrEMBL C6A666  DNA topoisomerase
[B] Bifidobacterium longumBIFLO01117  UniProtKB/TrEMBL Q8G6Z5  DNA topoisomerase
[B] Bifidobacterium longum (strain DJO10A)BIFLD01258  UniProtKB/TrEMBL B3DUA2  Topoisomerase I
[B] Bacteroides fragilisBACFR04392  UniProtKB/TrEMBL Q64MY0  DNA topoisomerase
[B] Bacteroides fragilis (strain ATCC 25285 / NCTC 9343)BACFN04103  UniProtKB/TrEMBL Q5L7R0  Similar to Zymomonas mobilis DNA topoisomerase I TopA SWALL:TOP1_ZYMMO (SWALL:Q9X3X7) (1217 aa) fasta scores: E(): 1.3e-73, 39.36% id in 663 aa, and to Bacteroides thetaiotaomicron DNA topoisomerase I BT2827 SWALL:Q8A3X7 (EMBL:AE016937) (782 aa) fasta scores: E(): 0, 82.35% id in 782 aa, and to Porphyromonas gingivalis W83 DNA topoisomerase I TopA or PG0754 SWALL:AAQ65921 (EMBL:AE017174) (788 aa) fasta scores: E(): 3.5e-169, 59.82% id in 779 aa putative DNA topoisomerase I
[B] Bacteroides thetaiotaomicronBACTN02794  UniProtKB/TrEMBL Q8A3X7  DNA topoisomerase
[B] Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154)BACV801235  UniProtKB/TrEMBL A6L010  DNA topoisomerase I
[B] Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)PARD803485  UniProtKB/TrEMBL A6LHY3  DNA topoisomerase I
[B] Porphyromonas gingivalisPORGI00646  UniProtKB/TrEMBL Q7MW85  DNA topoisomerase
[B] Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257)PORG300741  UniProtKB/TrEMBL B2RIV5  DNA topoisomerase I
[B] Amoebophilus asiaticus (strain 5a2)AMOA500991  UniProtKB/TrEMBL B3ETD4  Putative uncharacterized protein
[B] Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / VPI 2845)CAPOD00330  UniProtKB/TrEMBL C7M620  DNA topoisomerase I
[B] Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)FLAPJ01918  UniProtKB/TrEMBL A6H115  DNA topoisomerase I
[B] Gramella forsetii (strain KT0803)GRAFK02941  UniProtKB/TrEMBL A0M5R7  DNA topoisomerase I
[B] Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034)CHIPD01939  UniProtKB/TrEMBL C7PC68  DNA topoisomerase
[B] Salinibacter ruber (strain DSM 13855)SALRD01077  UniProtKB/TrEMBL Q2S3I6  DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051
[B] Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)CYTH302301  UniProtKB/TrEMBL Q11SL3  DNA topoisomerase type I (omega protein)
[B] Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114)DYAFD01179  UniProtKB/TrEMBL C6W599  DNA topoisomerase
[B] Acaryochloris marina (strain MBIC 11017)ACAM101906  UniProtKB/TrEMBL B0CFN9  DNA topoisomerase I
[B] Cyanothece sp. (strain PCC 8802)CYAP000832  UniProtKB/TrEMBL C7QKW5  DNA topoisomerase I
[B] Microcystis aeruginosa (strain NIES-843)MICAN05310  UniProtKB/TrEMBL B0JHS3  DNA topoisomerase
[B] Synechococcus sp. (strain CC9605)SYNSC00586  UniProtKB/TrEMBL Q3AM11  DNA topoisomerase I
[B] Synechococcus sp. (strain CC9902)SYNS901747  UniProtKB/TrEMBL Q3AWJ8  DNA topoisomerase I
[B] Synechococcus sp. (strain JA-2-3B'a(2-13))SYNJB02259  UniProtKB/TrEMBL Q2JJ84  DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051
[B] Synechococcus sp. (strain JA-3-3Ab)SYNJA00529  UniProtKB/TrEMBL Q2JWS9  DNA topoisomerase I identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01051
[B] Synechococcus sp. (strain PCC 6301)SYNP600138  UniProtKB/TrEMBL Q5N5T9  DNA topoisomerase I
[B] Synechococcus sp. (strain RCC307)SYNR300659  UniProtKB/TrEMBL A5GRQ4  DNA topoisomerase I
[B] Synechococcus sp. (strain WH7803)SYNPW01880  UniProtKB/TrEMBL A5GMZ4  DNA topoisomerase I
[B] Synechococcus sp. (strain WH8102)SYNPX01871  UniProtKB/TrEMBL Q7U539  DNA topoisomerase
[B] Synechocystis sp. (strain PCC 6803)SYNY301276  UniProtKB/Swiss-Prot TOP1_SYNY3  DNA topoisomerase 1
[B] Thermosynechococcus elongatus (strain BP-1)THEEB01852  UniProtKB/TrEMBL Q8DHR4  DNA topoisomerase I
[B] Anabaena variabilis (strain ATCC 29413 / PCC 7937)ANAVT00030  UniProtKB/TrEMBL Q3MH80  DNA topoisomerase I
[B] Anabaena sp. (strain PCC 7120)ANASP02748  UniProtKB/TrEMBL Q8YTE2  DNA topoisomerase
[B] Nostoc punctiforme (strain ATCC 29133 / PCC 73102)NOSP704047  UniProtKB/TrEMBL B2IWS5  DNA topoisomerase I
[B] Trichodesmium erythraeum (strain IMS101)TRIEI00019  UniProtKB/TrEMBL Q11AC4  DNA topoisomerase I
[B] Prochlorococcus marinusPROMA00432  UniProtKB/TrEMBL Q7VDE6  DNA topoisomerase
[B] Prochlorococcus marinus (strain MIT 9211)PROM400433  UniProtKB/TrEMBL A9BE54  DNA topoisomerase
[B] Prochlorococcus marinus (strain MIT 9215)PROM200513  UniProtKB/TrEMBL A8G3F0  DNA topoisomerase I
[B] Prochlorococcus marinus (strain MIT 9301)PROM000461  UniProtKB/TrEMBL A3PBF8  Prokaryotic DNA topoisomerase COG550 Topoisomerase IA [DNA replication, recombination, and repair]
[B] Prochlorococcus marinus (strain MIT 9303)PROM300621  UniProtKB/TrEMBL A2C7C2  Prokaryotic DNA topoisomerase
[B] Prochlorococcus marinus (strain MIT 9312)PROM900460  UniProtKB/TrEMBL Q31C99  DNA topoisomerase I
[B] Prochlorococcus marinus (strain MIT 9313)PROMM01346  UniProtKB/TrEMBL Q7V627  Prokaryotic DNA topoisomerase
[B] Prochlorococcus marinus (strain MIT 9515)PROM500498  UniProtKB/TrEMBL A2BV96  Prokaryotic DNA topoisomerase COG550 Topoisomerase IA [DNA replication, recombination, and repair]
[B] Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4)PROMP00490  UniProtKB/TrEMBL Q7V2N7  DNA topoisomerase
[B] Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923)DEIDV00800  UniProtKB/TrEMBL C1D174  Putative DNA topoisomerase
[B] Deinococcus geothermalis (strain DSM 11300)DEIGD01975  UniProtKB/TrEMBL Q1IWT9  DNA topoisomerase I KEGG: dra:DR1374 DNA topoisomerase I, ev=0.0, 79% identity TIGRFAM: DNA topoisomerase I: (0) PFAM: TOPRIM: (5.6e-39) DNA topoisomerase, type IA, central: (4.8e-183) SMART: DNA topoisomerase, type IA, domain 2: (1.8e-50) DNA topoisomerase, type IA, DNA-binding: (2.8e-119) Toprim subdomain: (2e-39)
[B] Deinococcus radioduransDEIRA01344  UniProtKB/TrEMBL Q9RUL0  DNA topoisomerase
[B] Rhodopirellula balticaRHOBA04416  UniProtKB/TrEMBL Q7UMV5  PMID: 8921893 best DB hits: BLAST: swissprot:Q9X909; TOP1_STRCO DNA TOPOISOMERASE I (OMEGA-PROTEIN); E=0.0 pir:G75403; DNA topoisomerase I - Deinococcus radiodurans (strain; E=0.0 swissprot:Q59567; TOP1_MYCTU DNA TOPOISOMERASE I (OMEGA-PROTEIN); E=0.0 COG: DR1374_1; COG0550 Topoisomerase IA; E=1e-170 PFAM: PF01751; Toprim domain; E=3.1e-39 PF01131; DNA topoisomerase; E=4e-164 DNA topoisomerase I
[B] Caulobacter crescentusCAUCR02418  UniProtKB/TrEMBL Q9A5J6  DNA topoisomerase
[B] Caulobacter crescentus (strain NA1000 / CB15N)CAUCN02516  UniProtKB/TrEMBL B8GZL1  DNA topoisomerase
[B] Caulobacter sp. (strain K31)CAUSK01466  UniProtKB/TrEMBL B0T0I9  DNA topoisomerase I
[B] Phenylobacterium zucineum (strain HLK1)PHEZH01313  UniProtKB/TrEMBL B4R961  DNA topoisomerase I
[B] Bartonella bacilliformis (strain ATCC 35685 / KC583)BARBK00762  UniProtKB/TrEMBL A1UT28  DNA topoisomerase I
[B] Bartonella henselaeBARHE00782  UniProtKB/TrEMBL Q6G3F7  DNA topoisomerase I
[B] Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712)BEII903305  UniProtKB/TrEMBL B2IEN4  DNA topoisomerase I
[B] Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)METSB03742  UniProtKB/TrEMBL B8EMQ0  DNA topoisomerase I
[B] Bradyrhizobium japonicumBRAJA05055  UniProtKB/TrEMBL Q89K08  DNA topoisomerase
[B] Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)BRASB04421  UniProtKB/TrEMBL A5EKR5  DNA topoisomerase I
[B] Bradyrhizobium sp. (strain ORS278)BRASO04260  UniProtKB/TrEMBL A4YWH0  DNA topoisomerase I
[B] Nitrobacter hamburgensis (strain X14 / DSM 10229)NITHX02293  UniProtKB/TrEMBL Q1QKM0  DNA topoisomerase
[B] Rhodopseudomonas palustrisRHOPA03115  UniProtKB/TrEMBL Q6N559  DNA topoisomerase
[B] Rhodopseudomonas palustris (strain BisA53)RHOP503330  UniProtKB/TrEMBL Q07L73  DNA topoisomerase I KEGG: rpc:RPC_2239 DNA topoisomerase TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Rhodopseudomonas palustris (strain BisB18)RHOPB02201  UniProtKB/TrEMBL Q215Z3  DNA topoisomerase
[B] Rhodopseudomonas palustris (strain BisB5)RHOPS03013  UniProtKB/TrEMBL Q135I0  DNA topoisomerase
[B] Rhodopseudomonas palustris (strain HaA2)RHOP202410  UniProtKB/TrEMBL Q2IXD6  DNA topoisomerase
[B] Rhodopseudomonas palustris (strain TIE-1)RHOPT03470  UniProtKB/TrEMBL B3Q9Y2  DNA topoisomerase I
[B] Brucella abortusBRUAB02597  UniProtKB/TrEMBL Q578A3  similar to BRA0604, DNA topoisomerase I TopA, DNA topoisomerase I
[B] Brucella abortus (strain 2308)BRUA202805  UniProtKB/TrEMBL Q2YKM3  DNA topoisomerase I:DNA topoisomerase I, ATP-binding:DNA topoisomerase I, DNA-binding:Bacterial DNA topoisomerase I:Toprim su...
[B] Brucella canis (strain ATCC 23365 / NCTC 10854)BRUC202659  UniProtKB/TrEMBL A9MBP4  DNA topoisomerase I
[B] Brucella melitensisBRUME02709  UniProtKB/TrEMBL Q8YC66  DNA TOPOISOMERASE I
[B] Brucella melitensis biotype 2 (strain ATCC 23457)BRUMB02568  UniProtKB/TrEMBL C0RLC5  DNA topoisomerase
[B] Brucella microti (strain CCM 4915)BRUMC02689  UniProtKB/TrEMBL C7LI90  DNA topoisomerase
[B] Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)BRUO202367  UniProtKB/TrEMBL A5VUT6  DNA topoisomerase I
[B] Brucella suisBRUSU02683  UniProtKB/TrEMBL D0PFV6  identified by match to TIGR protein family HMM TIGR01054 DNA topoisomerase I
[B] Brucella suis (strain ATCC 23445 / NCTC 10510)BRUSI02458  UniProtKB/TrEMBL A9WYS3  DNA topoisomerase I GO_component: cytoplasm [GO ID 0005737]; GO_function: DNA binding [GO ID 0003677]; GO_process: DNA replication [GO ID 0006260]
[B] Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)OCHA403621  UniProtKB/TrEMBL A6X573  DNA topoisomerase
[B] Methylobacterium extorquens (strain PA1)METEP03259  UniProtKB/TrEMBL A9W733  DNA topoisomerase I
[B] Methylobacterium nodulans (strain ORS2060 / LMG 21967)METNO03104  UniProtKB/TrEMBL B8IL44  DNA topoisomerase I
[B] Methylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)METPB03448  UniProtKB/TrEMBL B1ZKT9  DNA topoisomerase I
[B] Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831)METRJ00983  UniProtKB/TrEMBL B1M0P4  DNA topoisomerase
[B] Methylobacterium sp. (strain 4-46)METS404066  UniProtKB/TrEMBL B0UIR7  DNA topoisomerase I
[B] Mesorhizobium sp. (strain BNC1)MESSB01345  UniProtKB/TrEMBL Q11IM5  DNA topoisomerase I KEGG: mlo:mlr0839 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain containing protein DNA topoisomerase, type IA, central DNA topoisomerase, type IA, zn finger SMART: DNA topoisomerase, type IA, domain 2 DNA topoisomerase, type IA, DNA-binding Toprim subdomain
[B] Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)PARL102759  UniProtKB/TrEMBL A7HX05  DNA topoisomerase
[B] Agrobacterium tumefaciens (strain C58 / ATCC 33970)AGRT501276  UniProtKB/TrEMBL A9CJ93  DNA topoisomerase
[B] Rhizobium etli (strain CIAT 652)RHIE601687  UniProtKB/TrEMBL B3PW33  DNA topoisomerase I protein
[B] Rhizobium melilotiRHIME01286  UniProtKB/TrEMBL Q92QL9  Product confidence : putative Gene name confidence : putative predicted by Codon_usage predicted by Homology predicted by FrameD PUTATIVE DNA TOPOISOMERASE I PROTEIN
[B] Sinorhizobium medicae (strain WSM419)SINMW00923  UniProtKB/TrEMBL A6U807  DNA topoisomerase
[B] Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)AZOC501855  UniProtKB/TrEMBL A8I2E5  DNA topoisomerase I
[B] Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)XANP203817  UniProtKB/TrEMBL A7IM95  DNA topoisomerase
[B] Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418)HIRBI01970  UniProtKB/TrEMBL C6XL73  DNA topoisomerase I
[B] Maricaulis maris (strain MCS10)MARMM01278  UniProtKB/TrEMBL Q0AQ63  DNA topoisomerase I
[B] Paracoccus denitrificans (strain Pd 1222)PARDP00639  UniProtKB/TrEMBL A1AZS7  DNA topoisomerase I KEGG: rsp:RSP_2178 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)RHOS400760  UniProtKB/TrEMBL Q3J4F4  Brings about the conversion of one topological isomer of DNA into another, e.g. the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of compleme Citation: Bensaid A, Almeida A, Drlica K, Rouviere-Yaniv J. J Mol Biol. 1996 Feb 23;256(2):292-300. PMID: 8594197 DNA topoisomerase I
[B] Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)RHOS100824  UniProtKB/TrEMBL A3PHZ5  DNA topoisomerase I KEGG: rsp:RSP_2178 DNA topoisomerase I TIGRFAM: DNA topoisomerase I PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein
[B] Rhodobacter sphaeroides (strain KD131 / KCTC 12085)RHOSK00474  UniProtKB/TrEMBL B9KNS1  DNA topoisomerase I
[B] Roseobacter denitrificans (strain ATCC 33942 / OCh 114)ROSDO01981  UniProtKB/TrEMBL Q167W6  DNA topoisomerase I, putative
[B] Silicibacter pomeroyiSILPO02999  UniProtKB/TrEMBL Q5LNX4  identified by match to protein family HMM PF01131; match to protein family HMM PF01396; match to protein family HMM PF01751; match to protein family HMM TIGR01051 DNA topoisomerase I
[B] Silicibacter sp. (strain TM1040)SILST02330  UniProtKB/TrEMBL Q1GE45  DNA topoisomerase I KEGG: sil:SPO3079 DNA topoisomerase I, ev=0.0, 77% identity TIGRFAM: DNA topoisomerase I: (4.5e-272) PFAM: TOPRIM: (5.9e-29) DNA topoisomerase, type IA, central: (5.3e-138) DNA topoisomerase, type IA, zn finger: (3.4e-13) SMART: DNA topoisomerase, type IA, domain 2: (1.7e-46) DNA topoisomerase, type IA, DNA-binding: (2.5e-105) Toprim subdomain: (8.9e-30)
[B] Acetobacter pasteurianus (strain NBRC 3283 / LMG 1513 / CCTM 1153)ACEP300719  UniProtKB/TrEMBL C7JES1  DNA topoisomerase I
[B] Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)GLUDA00039  UniProtKB/TrEMBL A9GZQ5  DNA topoisomerase I
[B] Gluconobacter oxydansGLUOX01212  UniProtKB/TrEMBL Q5FRH2  DNA topoisomerase I
[B] Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)GRABC00804  UniProtKB/TrEMBL Q0BU00  DNA topoisomerase I
[B] Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)MAGSA00678  UniProtKB/TrEMBL Q2W9I9  DNA topoisomerase
[B] Rhodospirillum centenum (strain ATCC 51521 / SW)RHOCS01476  UniProtKB/TrEMBL B6IN35  DNA topoisomerase I
[B] Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)RHORT03189  UniProtKB/TrEMBL Q2RPE8  DNA topoisomerase
[B] Erythrobacter litoralis (strain HTCC2594)ERYLH00956  UniProtKB/TrEMBL Q2NB87  DNA topoisomeraseI COG0550 topoisomeraseIA
[B] Novosphingobium aromaticivorans (strain DSM 12444)NOVAD01786  UniProtKB/TrEMBL Q2G7D0  DNA topoisomerase
[B] Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)SPHWW03778  UniProtKB/TrEMBL A5VD05  DNA topoisomerase I
[B] Sphingopyxis alaskensisSPHAL01196  UniProtKB/TrEMBL Q1GTU5  DNA topoisomerase
[B] Thiobacillus denitrificans (strain ATCC 25259)THIDA00010  UniProtKB/TrEMBL Q3SMS7  DNA topoisomerase I
[B] Methylobacillus flagellatus (strain KT / ATTC 51484 / DSM 6875)METFK00227  UniProtKB/TrEMBL Q1H4T9  DNA topoisomerase
[B] Methylovorus sp. (strain SIP3-4)METSD00244  UniProtKB/TrEMBL C6X8M3  DNA topoisomerase I
[B] Arcobacter butzleri (strain RM4018)ARCB402159  UniProtKB/TrEMBL A8EWX5  DNA topoisomerase I
[B] Alkalilimnicola ehrlichei (strain MLHE-1)ALHEH02610  UniProtKB/TrEMBL Q0A5B5  DNA topoisomerase I
[B] Halorhodospira halophila (strain DSM 244 / SL1)HALHL02292  UniProtKB/TrEMBL A1WZH7  DNA topoisomerase I
[B] Thioalkalivibrio sp. (strain HL-EbGR7)THISH00183  UniProtKB/TrEMBL B8GU07  DNA topoisomerase
[B] Thiomicrospira crunogena (strain XCL-2)THICR00195  UniProtKB/TrEMBL Q31J81  DNA topoisomerase
[B] Stenotrophomonas maltophilia (strain K279a)STRMK03928  UniProtKB/TrEMBL B2FIS0  Putative DNA topoisomerase I
[B] Stenotrophomonas maltophilia (strain R551-3)STRM503572  UniProtKB/TrEMBL B4SKI3  DNA topoisomerase I
[B] Xanthomonas axonopodis pv. citriXANAC03706  UniProtKB/TrEMBL Q8PG14  DNA topoisomerase
[B] Xanthomonas campestris pv. campestrisXANCP03650  UniProtKB/TrEMBL Q8P4F3  DNA topoisomerase
[B] Xanthomonas campestris pv. campestris (strain 8004)XANC803717  UniProtKB/TrEMBL Q4UQ08  DNA topoisomerase I
[B] Xanthomonas campestris pv. campestris (strain B100)XANCB03920  UniProtKB/TrEMBL B0RWR4  DNA topoisomerase I
[B] Xanthomonas campestris pv. vesicatoria (strain 85-10)XANC503843  UniProtKB/TrEMBL Q3BNK0  DNA topoisomerase I
[B] Xanthomonas oryzae (pv. oryzae)XANOR00504  UniProtKB/TrEMBL Q5H5D7  identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark DNA topoisomerase I
[B] Xanthomonas oryzae pv. oryzae (strain MAFF 311018)XANOM00488  UniProtKB/TrEMBL Q2P832  DNA topoisomerase I identified by sequence similarity; putative; ORF located using Blastx/Glimmer/GeneHacker
[B] Xanthomonas oryzae pv. oryzae (strain PXO99A)XANOP00620  UniProtKB/TrEMBL B2SL47  DNA topoisomerase I
[B] Xylella fastidiosaXYLFA00889  UniProtKB/Swiss-Prot TOP1_XYLFA  DNA topoisomerase 1
[B] Xylella fastidiosa (strain M12)XYLFM01705  UniProtKB/TrEMBL B0U4M9  DNA topoisomerase
[B] Xylella fastidiosa (strain M23)XYLF201768  UniProtKB/TrEMBL B2I8S8  DNA topoisomerase I
[B] Xylella fastidiosa (strain Temecula1 / ATCC 700964)XYLFT01661  UniProtKB/Swiss-Prot TOP1_XYLFT  DNA topoisomerase 1
[B] Ruthia magnifica subsp. Calyptogena magnificaRUTMC00935  UniProtKB/TrEMBL A1AXT2  DNA topoisomerase I
[B] Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)VESOH00897  UniProtKB/TrEMBL A5CVH7  DNA topoisomerase I
[B] Borrelia afzelii (strain PKo)BORAP00838  UniProtKB/TrEMBL Q0SM23  DNA topoisomerase I
[B] Borrelia burgdorferiBORBU00827  UniProtKB/Swiss-Prot TOP1_BORBU  DNA topoisomerase 1
[B] Borrelia burgdorferi (strain ZS7)BORBZ00791  UniProtKB/TrEMBL B7J0S2  DNA topoisomerase I
[B] Borrelia duttonii (strain Ly)BORDL00798  UniProtKB/TrEMBL B5RN26  DNA topoisomerase I
[B] Borrelia hermsii (strain DAH)BORHD00802  UniProtKB/TrEMBL B2S1H2  DNA topoisomerase I
[B] Borrelia recurrentis (strain A1)BORRA00783  UniProtKB/TrEMBL B5RQG5  DNA topoisomerase I
[B] Borrelia turicatae (strain 91E135)BORT900800  UniProtKB/TrEMBL A1R0Q3  DNA topoisomerase I