| [E] Homo sapiens | HUMAN06130 | DYR_HUMAN | - |
| [E] Pan troglodytes | PANTR05121 | ENSPTRP00000029175 | - |
| [A] Haloquadratum walsbyi (strain DSM 16790) | HALWD01519 | Q18HG9 | dihydrofolate reductase |
| [A] Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) | HALLT02121 | B9LR90 | Dihydrofolate reductase region |
| [A] Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) | NATPD01451 | Q3IQP3 | dihydrofolate reductase (EC 1.5.1.3) |
| [B] Rhodococcus erythropolis (strain PR4 / NBRC 100887) | RHOE404452 | C0ZMB2 | Dihydrofolate reductase |
| [B] Rhodococcus opacus (strain B4) | RHOOB01962 | C1B0L0 | Dihydrofolate reductase |
| [B] Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) | KINRD04397 | A6WGF8 | Dihydrofolate reductase |
| [B] Leifsonia xyli (subsp. xyli) | LEIXX00745 | Q6AFI1 | identified by sequence similarity dihydrofolate reductase |
| [B] Symbiobacterium thermophilum | SYMTH03064 | Q67JQ2 | dihydrofolate reductase |
| [B] Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) | BACV801820 | A6L1Q7 | Dihydrofolate reductase |
| [B] Porphyromonas gingivalis | PORGI01717 | Q7MTB4 | similar to GB:X63753, GB:S47238, GB:S47239, GB:S47240, GB:S79056, SP:P18583, PID:338290, and PID:36546; identified by sequence similarity; putative dihydrofolate reductase |
| [B] Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) | PORG301991 | B2RMI4 | Probable dihydrofolate reductase |
| [B] Amoebophilus asiaticus (strain 5a2) | AMOA500268 | B3ER85 | Putative uncharacterized protein |
| [B] Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) | FLAJ101462 | A5FJX2 | Dihydrofolate reductase |
| [B] Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511) | FLAPJ00320 | A6GWG8 | Dihydrofolate reductase |
| [B] Gramella forsetii (strain KT0803) | GRAFK00274 | A0LY20 | dihydrofolate reductase |
| [B] Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) | CYTH301544 | Q11US6 | dihydrofolate reductase type I; trimethoprim resistance |
| [B] Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) | DEIDV02538 | C1D068 | Putative dihydrofolate reductase |
| [B] Deinococcus radiodurans | DEIRA02558 | Q9RR65 | Dihydrofolate reductase |
| [B] Bacillus amyloliquefaciens (strain FZB42) | BACA201909 | A7Z5T2 | DfrA |
| [B] Bacillus anthracis | BACAN02050 | B0AVP0 | similar to SP:P11045, GB:M99701, and PID:521207; identified by sequence similarity; putative dihydrofolate reductase |
| [B] Bacillus cereus (strain AH187) | BACC702160 | B7HQ33 | Dihydrofolate reductase |
| [B] Bacillus cereus (strain ATCC 10987) | BACC102241 | Q738X6 | identified by match to protein family HMM PF00186 dihydrofolate reductase |
| [B] Bacillus cereus (strain ATCC 14579 / DSM 31) | BACCR02044 | Q81E04 | Dihydrofolate reductase |
| [B] Bacillus cereus (strain G9842) | BACC202061 | B7IV73 | Dihydrofolate reductase |
| [B] Bacillus cereus (strain ZK) | BACCZ01994 | Q63BV4 | dihydrofolate reductase |
| [B] Bacillus cereus subsp. cytotoxis (strain NVH 391-98) | BACCN01573 | A7GP91 | Dihydrofolate reductase |
| [B] Bacillus halodurans | BACHD03392 | Q9K7B6 | dihydrofolate reductase |
| [B] Bacillus licheniformis (strain DSM 13 / ATCC 14580) | BACLD02192 | Q65IB5 | InterProMatches:IPR001796; glycine/purine/DNA precursor synthesis, conversion of dUMP to dTMP,Molecular Function: dihydrofolate reductase activity (GO:0004146), Biological Process: glycine biosynthesis (GO:0006545), Biological Process: nucleotide biosynthesis (GO:0009165) dihydrofolate reductase |
| [B] Bacillus pumilus (strain SAFR-032) | BACP201880 | A8FEB8 | Dihydrofolate reductase |
| [B] Bacillus subtilis | BACSU02180 | DYR_BACSU | Dihydrofolate reductase |
| [B] Bacillus thuringiensis (strain Al Hakam) | BACAH01887 | A0RDM0 | dihydrofolate reductase |
| [B] Bacillus thuringiensis (subsp. konkukian) | BACHK01979 | Q6HJC6 | dihydrofolate reductase |
| [B] Bacillus weihenstephanensis (strain KBAB4) | BACWK02018 | A9VTX1 | Dihydrofolate reductase |
| [B] Geobacillus kaustophilus | GEOKA01759 | Q5KZ26 | dihydrofolate reductase |
| [B] Geobacillus thermodenitrificans (strain NG80-2) | GEOTN01629 | A4INY0 | Dihydrofolate reductase |
| [B] Lysinibacillus sphaericus (strain C3-41) | LYSSC02616 | B1HZG5 | Dihydrofolate reductase type 3 |
| [B] Listeria monocytogenes | LISMO01869 | C8JS20 | similar to dihydrofolate reductases |
| [B] Listeria monocytogenes (serotype 4b / strain F2365) | LISMF01881 | Q71YE2 | identified by match to protein family HMM PF00186 dihydrofolate reductase |
| [B] Listeria monocytogenes serotype 4a (strain HCC23) | LISMH00671 | B8DDM9 | Dihydrofolate reductase |
| [B] Listeria monocytogenes serotype 4b (strain Clip81459) | LISMC01858 | C1KWH3 | Putative dihydrofolate reductase |
| [B] Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334) | LISW601891 | A0AJX9 | DfrA protein |
| [B] Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) | BREBN04325 | C0ZI90 | Dihydrofolate reductase |
| [B] Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) | CLOB804852 | A6M379 | Dihydrofolate reductase |
| [B] Clostridium botulinum (strain Alaska E43 / type E3) | CLOBA03125 | B2V0W4 | Dihydrofolate reductase |
| [B] Clostridium botulinum (strain Eklund 17B / type B) | CLOBB03356 | B2TR57 | Dihydrofolate reductase |
| [B] Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) | CLOCE01251 | B8I0T9 | dihydrofolate reductase region PFAM: dihydrofolate reductase region; KEGG: gtn:GTNG_1670 dihydrofolate reductase |
| [B] Clostridium novyi (strain NT) | CLONN00315 | A0PY39 | dihydrofolate reductase identified by match to protein family HMM PF00186 |
| [B] Clostridium perfringens | CLOPE00044 | Q8XPC1 | Probable dihydrofolate reductase |
| [B] Clostridium perfringens (strain ATCC 13124 / NCTC 8237) | CLOP100042 | Q0TV23 | dihydrofolate reductase identified by similarity to SP:P11045; match to protein family HMM PF00186 |
| [B] Clostridium perfringens (strain SM101) | CLOPS00045 | Q0SWS9 | dihydrofolate reductase identified by match to protein family HMM PF00186 |
| [B] Enterococcus faecalis | ENTFA01469 | C0X5G6 | Dihydrofolate reductase |
| [B] Lactobacillus plantarum | LACPL01559 | C2FIE9 | dihydrofolate reductase |
| [B] Leuconostoc citreum (strain KM20) | LEUCK00687 | B1MYC2 | Dihydrofolate reductase |
| [B] Caulobacter crescentus | CAUCR02095 | Q9A6G8 | Dihydrofolate reductase |
| [B] Caulobacter sp. (strain K31) | CAUSK03324 | B0T4Y7 | Dihydrofolate reductase precursor |
| [B] Phenylobacterium zucineum (strain HLK1) | PHEZH00817 | B4RGA7 | Dihydrofolate reductase |
| [B] Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) | BRASB05685 | A5EPD1 | Dihydrofolate reductase |
| [B] Bradyrhizobium sp. (strain ORS278) | BRASO05259 | A4YZC2 | Dihydrofolate reductase |
| [B] Nitrobacter hamburgensis (strain X14 / DSM 10229) | NITHX02569 | Q1QJT9 | Dihydrofolate reductase |
| [B] Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391) | NITWN02217 | Q3SQ37 | dihydrofolate reductase region |
| [B] Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) | OLICO01257 | B6JB68 | Dihydrofolate reductase |
| [B] Rhodopseudomonas palustris (strain BisA53) | RHOP502146 | Q07PL3 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: rpc:RPC_3263 dihydrofolate reductase |
| [B] Rhodopseudomonas palustris (strain BisB5) | RHOPS03330 | Q134B2 | Dihydrofolate reductase |
| [B] Brucella abortus | BRUAB01293 | C4IS81 | similar to BR1398, dihydrofolate reductase FolA, dihydrofolate reductase |
| [B] Brucella abortus (strain 2308) | BRUA201403 | Q2YS23 | Dihydrofolate reductase |
| [B] Brucella abortus (strain S19) | BRUA101250 | B2S6M2 | Dihydrofolate reductase |
| [B] Brucella canis (strain ATCC 23365 / NCTC 10854) | BRUC201345 | A9M656 | Dihydrofolate reductase type 3 |
| [B] Brucella melitensis | BRUME00607 | D0B8M8 | DIHYDROFOLATE REDUCTASE |
| [B] Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512) | BRUO201202 | A5VRE6 | Dihydrofolate reductase |
| [B] Brucella suis | BRUSU01345 | Q8FZS4 | identified by match to PFAM protein family HMM PF00186 dihydrofolate reductase |
| [B] Brucella suis (strain ATCC 23445 / NCTC 10510) | BRUSI01361 | B0CHI6 | Dihydrofolate reductase type 3 GO_function: dihydrofolate reductase activity [GO ID 0004146]; GO_process: glycine biosynthetic process [GO ID 0006545] |
| [B] Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) | OCHA401768 | A6WZV5 | Dihydrofolate reductase |
| [B] Methylobacterium nodulans (strain ORS2060 / LMG 21967) | METNO00662 | B8IF21 | Dihydrofolate reductase region |
| [B] Mesorhizobium sp. (strain BNC1) | MESSB01739 | Q11HI1 | dihydrofolate reductase region PFAM: dihydrofolate reductase region KEGG: bmb:BruAb1_1393 FolA, dihydrofolate reductase |
| [B] Rhizobium loti | RHILO01144 | Q98KI7 | dihydrofolate reductase |
| [B] Agrobacterium radiobacter (strain K84 / ATCC BAA-868) | AGRRK02184 | B9JGK8 | Dihydrofolate reductase protein |
| [B] Agrobacterium tumefaciens (strain C58 / ATCC 33970) | AGRT501995 | A9CIC8 | Dihydrofolate reductase |
| [B] Rhizobium meliloti | RHIME02102 | Q92NQ7 | Product confidence : probable Gene name confidence : probable predicted by Codon_usage predicted by Homology predicted by FrameD PROBABLE DIHYDROFOLATE REDUCTASE PROTEIN |
| [B] Sinorhizobium medicae (strain WSM419) | SINMW01970 | A6UB22 | Dihydrofolate reductase |
| [B] Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) | XANP201365 | A7IF75 | Dihydrofolate reductase |
| [B] Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) | RHOS401993 | Q3J0X0 | Dihydrofolate reductase |
| [B] Rhodobacter sphaeroides (strain KD131 / KCTC 12085) | RHOSK01698 | B9KKD1 | Dihydrofolate reductase |
| [B] Roseobacter denitrificans (strain ATCC 33942 / OCh 114) | ROSDO01740 | Q168V7 | dihydrofolate reductase |
| [B] Silicibacter sp. (strain TM1040) | SILST01720 | Q1GFV5 | Dihydrofolate reductase PFAM: dihydrofolate reductase region: (5.1e-44) KEGG: rsp:RSP_0389 dihydrofolate reductase, ev=3e-49, 59% identity |
| [B] Bordetella avium (strain 197N) | BORA100495 | Q2KYI7 | dihydrofolate reductase |
| [B] Bordetella bronchiseptica | BORBR00866 | Q7WP14 | ortholog of Bordetella pertussis (BX470248) BP3155 dihydrofolate reductase |
| [B] Bordetella parapertussis | BORPA00780 | Q7W1B0 | ortholog of Bordetella pertussis (BX470248) BP3155 dihydrofolate reductase |
| [B] Bordetella pertussis | BORPE02889 | Q7VUE2 | Similar to Escherichia coli dihydrofolate reductase FolA or TmrA or B0048 SW:DYR_ECOLI (P00379) (159 aa) fasta scores: E(): 1.9e-23, 46.54% id in 159 aa, and to Salmonella typhimurium dihydrofolate reductase type III DhfrIII SW:DYR3_SALTY (P12833) (162 aa) fasta scores: E(): 3.6e-25, 47.17% id in 159 aa dihydrofolate reductase |
| [B] Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) | BORPD03960 | A9I779 | FolA protein |
| [B] Burkholderia ambifaria (strain MC40-6) | BURA400948 | B1YV70 | Dihydrofolate reductase |
| [B] Burkholderia cenocepacia (strain AU 1054) | BURCA00596 | Q1BXZ1 | Dihydrofolate reductase |
| [B] Burkholderia cenocepacia (strain HI2424) | BURCH01074 | A0K5Q8 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: bcn:Bcen_0603 dihydrofolate reductase |
| [B] Burkholderia cenocepacia (strain MC0-3) | BURCC01033 | B1JXV6 | Dihydrofolate reductase |
| [B] Burkholderia cepacia (strain ATCC 53795 / AMMD) | BURCM00953 | Q0BH56 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: bur:Bcep18194_A4196 dihydrofolate reductase |
| [B] Burkholderia cepacia (strain J2315 / LMG 16656) | BURCJ02792 | B4EAM3 | dihydrofolate reductase CDS is associated with trimethoprim resistance |
| [B] Burkholderia sp. (strain 383) | BURS301008 | Q39IC3 | Dihydrofolate reductase |
| [B] Burkholderia vietnamiensis (strain G4 / LMG 22486) | BURVG00970 | A4JCL0 | Dihydrofolate reductase |
| [B] Burkholderia mallei | BURMA00325 | A5JCE2 | Dihydrofolate reductase |
| [B] Burkholderia mallei (strain NCTC 10229) | BURM900852 | A2S4M4 | Dihydrofolate reductase |
| [B] Burkholderia mallei (strain NCTC 10247) | BURM700221 | A3MHT3 | Dihydrofolate reductase |
| [B] Burkholderia mallei (strain SAVP1) | BURMS02378 | A1V6H9 | Dihydrofolate reductase |
| [B] Burkholderia phymatum (strain DSM 17167 / STM815) | BURP800773 | B2JF42 | Dihydrofolate reductase |
| [B] Burkholderia phytofirmans (strain DSM 17436 / PsJN) | BURPP02882 | B2T5Z4 | Dihydrofolate reductase |
| [B] Burkholderia pseudomallei | BURPS02485 | A4LE85 | Similar to Escherichia coli dihydrofolate reductase FolA or TmrA or b0048 SWALL:DYR_ECOLI (SWALL:P00379) (159 aa) fasta scores: E(): 4e-22, 45.34% id in 161 aa, and to Ralstonia solanacearum probable dihydrofolate reductase oxidoreductase protein rsc0946 or rs04449 SWALL:Q8Y0U7 (EMBL:AL646061) (167 aa) fasta scores: E(): 1.2e-42, 72.39% id in 163 aa dihydrofolate reductase |
| [B] Burkholderia pseudomallei (strain 1106a) | BURP002847 | A3NXS6 | Dihydrofolate reductase |
| [B] Burkholderia pseudomallei (strain 1710b) | BURP102890 | Q3JQ22 | dihydrofolate reductase identified by match to protein family HMM PF00186 |
| [B] Burkholderia pseudomallei (strain 668) | BURP602803 | A3NBZ0 | Dihydrofolate reductase |
| [B] Burkholderia xenovorans (strain LB400) | BURXL03300 | Q13VG2 | Dihydrofolate reductase |
| [B] Cupriavidus taiwanensis (strain R1 / LMG 19424) | CUPTR02138 | B3R5A7 | Dihydrofolate reductase type I |
| [B] Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) | RALEH02627 | Q0K888 | dihydrofolate reductase |
| [B] Ralstonia eutropha (strain JMP134) | RALEJ00908 | Q473Z0 | Dihydrofolate reductase |
| [B] Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) | RALME02520 | Q1LK80 | dihydrofolate reductase region |
| [B] Polynucleobacter necessarius (strain STIR1) | POLNS00335 | B1XTJ0 | Dihydrofolate reductase |
| [B] Polynucleobacter sp. (strain QLW-P1DMWA-1) | POLSQ00375 | A4SVT6 | Dihydrofolate reductase |
| [B] Ralstonia pickettii (strain 12J) | RALPJ00796 | B2U8M3 | Dihydrofolate reductase |
| [B] Ralstonia solanacearum | RALSO00942 | Q8Y0U7 | Product confidence : probable Gene name confidence : putative predicted by Codon_usage predicted by Homology predicted by FrameD PROBABLE DIHYDROFOLATE REDUCTASE OXIDOREDUCTASE PROTEIN |
| [B] Acidovorax avenae subsp. citrulli (strain AAC00-1) | ACIAC01384 | A1TM51 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: rfr:Rfer_2985 dihydrofolate reductase |
| [B] Acidovorax sp. (strain JS42) | ACISJ01148 | A1W5A2 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: pol:Bpro_1822 dihydrofolate reductase |
| [B] Diaphorobacter sp. (strain TPSY) | DIAST01097 | B9MG01 | Dihydrofolate reductase |
| [B] Polaromonas naphthalenivorans (strain CJ2) | POLNA02712 | A1VQZ7 | Dihydrofolate reductase |
| [B] Polaromonas sp. (strain JS666 / ATCC BAA-500) | POLSJ01781 | Q12CI7 | Dihydrofolate reductase |
| [B] Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) | RHOFD02918 | Q21U57 | Dihydrofolate reductase |
| [B] Verminephrobacter eiseniae (strain EF01-2) | VEREI03083 | A1WMP6 | Dihydrofolate reductase |
| [B] Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) | LEPCP01245 | B1Y5E0 | Dihydrofolate reductase |
| [B] Methylibium petroleiphilum (strain PM1) | METPP02012 | A2SHH1 | Dihydrofolate reductase |
| [B] Herminiimonas arsenicoxydans | HERAR00990 | A4G3Z7 | Dihydrofolate reductase |
| [B] Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) | JANMA01191 | A6SX85 | Dihydrofolate reductase |
| [B] Thiobacillus denitrificans (strain ATCC 25259) | THIDA02038 | Q3SH97 | dihydrofolate reductase |
| [B] Methylobacillus flagellatus (strain KT / ATTC 51484 / DSM 6875) | METFK00910 | Q1H2G1 | Dihydrofolate reductase |
| [B] Chromobacterium violaceum | CHRVO01028 | Q7NZ94 | identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0262 dihydrofolate reductase |
| [B] Laribacter hongkongensis (strain HLHK9) | LARHH00762 | C1D4I6 | Dihydrofolate reductase |
| [B] Neisseria meningitidis serogroup C (strain 053442) | NEIM001730 | A9M313 | dihydrofolate reductase Code: H; COG: COG0262 |
| [B] Nitrosomonas europaea | NITEU00545 | Q82WU4 | Dihydrofolate reductase |
| [B] Nitrosomonas eutropha (strain C71) | NITEC00957 | Q0AHA5 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: neu:NE0567 dihydrofolate reductase |
| [B] Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) | NITMU01887 | Q2Y7L3 | Dihydrofolate reductase |
| [B] Azoarcus sp. (strain BH72) | AZOSB03187 | A1KAF8 | FolA protein Dihydrofolate reductase. catalytic activity: 5,6,7,8-tetrahydrofolate + nadp(+) = 7,8- dihydrofolate + nadph. pathway: essential step for de novo glycine and purine synthesis, dna precursor synthesis, and for the conversion of dump to dtmp. Pfam: Dihydrofolate reductase High confidence in function and specificity |
| [B] Azoarcus sp. (strain EbN1) | AZOSE02440 | Q5P234 | Dihydrofolate reductase |
| [B] Dechloromonas aromatica (strain RCB) | DECAR00574 | Q47IJ5 | Dihydrofolate reductase region |
| [B] Bdellovibrio bacteriovorus | BDEBA02961 | Q6MID1 | InterPro: Dihydrofolate reductase hypothetical protein |
| [B] Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) | GEOMG02853 | Q39RF9 | Dihydrofolate reductase region |
| [B] Geobacter sulfurreducens | GEOSL00561 | Q74FN5 | Dihydrofolate reductase |
| [B] Geobacter uraniumreducens (strain Rf4) | GEOUR00889 | A5GBA2 | Dihydrofolate reductase |
| [B] Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) | PELCD02915 | Q3A0W8 | Dihydrofolate reductase |
| [B] Myxococcus xanthus (strain DK 1622) | MYXXD05712 | Q1CZU3 | dihydrofolate reductase identified by similarity to SP:P11045; match to protein family HMM PF00186 |
| [B] Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) | AERHH03283 | A0KNL5 | dihydrofolate reductase identified by similarity to SP:P00379; match to protein family HMM PF00186 |
| [B] Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8) | MARAV02324 | A1U3D7 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: abo:ABO_2343 dihydrofolate reductase |
| [B] Colwellia psychrerythraea (strain 34H / ATCC BAA-681) | COLP304330 | Q47VL9 | identified by similarity to SP:P00379; match to protein family HMM PF00186 dihydrofolate reductase |
| [B] Idiomarina loihiensis | IDILO00476 | Q5R038 | Dihydrofolate reductase |
| [B] Psychromonas ingrahamii (strain 37) | PSYIN01009 | A1STR9 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: ilo:IL0478 dihydrofolate reductase |
| [B] Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) | SHEAM02808 | A1S9H0 | Dihydrofolate reductase KEGG: son:SO3646 dihydrofolate reductase |
| [B] Shewanella baltica (strain OS155 / ATCC BAA-1091) | SHEB500935 | A3D183 | Dihydrofolate reductase |
| [B] Shewanella baltica (strain OS185) | SHEB801012 | A6WK54 | Dihydrofolate reductase |
| [B] Shewanella baltica (strain OS195) | SHEB901061 | A9L433 | PFAM: dihydrofolate reductase region KEGG: shw:Sputw3181_3183 dihydrofolate reductase Dihydrofolate reductase |
| [B] Shewanella baltica (strain OS223) | SHEB203218 | B8EC01 | Dihydrofolate reductase |
| [B] Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) | SHEDO02876 | Q12K26 | Dihydrofolate reductase |
| [B] Shewanella frigidimarina (strain NCIMB 400) | SHEFN03030 | Q07YJ3 | Dihydrofolate reductase |
| [B] Shewanella loihica (strain BAA-1088 / PV-4) | SHELP00873 | A3QB98 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: son:SO3646 dihydrofolate reductase |
| [B] Shewanella oneidensis | SHEON03406 | Q8EB86 | Dihydrofolate reductase |
| [B] Shewanella pealeana (strain ANG-SQ1 / ATCC 700345) | SHEPA00839 | A8H0U7 | PFAM: dihydrofolate reductase region KEGG: shm:Shewmr7_3120 dihydrofolate reductase Dihydrofolate reductase |
| [B] Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) | SHEPC00958 | A4Y430 | Dihydrofolate reductase |
| [B] Shewanella sediminis (strain HAW-EB3) | SHESH00955 | A8FRU7 | KEGG: slo:Shew_0874 dihydrofolate reductase Dihydrofolate reductase |
| [B] Shewanella sp. (strain ANA-3) | SHESA03175 | A0L069 | dihydrofolate reductase region PFAM: dihydrofolate reductase region KEGG: son:SO3646 dihydrofolate reductase |
| [B] Shewanella sp. (strain MR-4) | SHESM00896 | Q0HLT7 | Dihydrofolate reductase |
| [B] Shewanella sp. (strain MR-7) | SHESR03088 | Q0HS01 | Dihydrofolate reductase |
| [B] Shewanella sp. (strain W3-18-1) | SHESW03112 | A1RMV3 | Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: shm:Shewmr7_3120 dihydrofolate reductase |
| [B] Shewanella woodyi (strain ATCC 51908 / MS32) | SHEWM00998 | B1KGH4 | Dihydrofolate reductase |
| [B] Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) | NITOC00207 | Q3JEI1 | Dihydrofolate reductase |
| [B] Alkalilimnicola ehrlichei (strain MLHE-1) | ALHEH00418 | Q0ABL0 | Dihydrofolate reductase |
| [B] Thioalkalivibrio sp. (strain HL-EbGR7) | THISH02707 | B8GN07 | Dihydrofolate reductase |
| [B] Buchnera aphidicola (subsp. Acyrthosiphon pisum) | BUCAI00133 | DYR_BUCAI | dihydrofolate reductase |
| [B] Buchnera aphidicola (subsp. Baizongia pistaciae) | BUCBP00123 | DYR_BUCBP | COG0262 dihydrofolate reductase |
| [B] Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A) | BUCA500129 | B8D8U4 | Dihydrofolate reductase |
| [B] Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7) | BUCAT00129 | B8D748 | Dihydrofolate reductase |
| [B] Erwinia tasmaniensis (strain DSM 17950 / ET1/99) | ERWT900721 | B2VGQ7 | Dihydrofolate reductase |
| [B] Erwinia carotovora (subsp. atroseptica) | ERWCT03829 | Q6D0D5 | Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri dihydrofolate reductase FolA or TmrA or b0048 or c0058 or sf0045 SWALL:DYR_ECOLI (SWALL:P00379) (159 aa) fasta scores: E(): 9e-51, 79.24% id in 159 aa dihydrofolate reductase |
| [B] Wigglesworthia glossinidia brevipalpis | WIGBR00022 | Q8D3H9 | Biosynthesis of cofactors, prosthetic groups, and carrier |
| [B] Blochmannia pennsylvanicus (strain BPEN) | BLOPB00119 | Q494F1 | ortholog to Escherichia coli bnum: b0048; MultiFun: Metabolism 1.5.3.2, 1.7.17 dihydrofolate reductase type I |
| [B] Coxiella burnetii | COXBU01887 | A9ZG78 | similar to GB:X63753, GB:S47238, GB:S47239, GB:S47240, GB:S79056, SP:P18583, PID:338290, PID:36546, GB:X63753, GB:S47238, GB:S47239, GB:S47240, GB:S79056, SP:P18583, PID:338290, and PID:36546; identified by sequence similarity; putative dihydrofolate reductase |
| [B] Coxiella burnetii (strain CbuG_Q212) | COXB201739 | B6J3B8 | Dihydrofolate reductase |
| [B] Coxiella burnetii (strain Dugway 5J108-111) | COXBN01944 | A9KH09 | Dihydrofolate reductase |
| [B] Coxiella burnetii (strain RSA 331 / Henzerling II) | COXBR00084 | A9N9I0 | Dihydrofolate reductase |
| [B] Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) | ALCBS02341 | Q0VM07 | Dihydrofolate reductase |
| [B] Hahella chejuensis (strain KCTC 2396) | HAHCH05519 | Q2SA18 | Dihydrofolate reductase COG0262 |
| [B] Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) | CHRSD02553 | Q1QUE0 | Dihydrofolate reductase |
| [B] Marinomonas sp. (strain MWYL1) | MARMS03675 | A6W1R3 | Dihydrofolate reductase |
| [B] Haemophilus influenzae | HAEIN00884 | DYR_HAEIN | Dihydrofolate reductase |
| [B] Haemophilus influenzae (strain 86-028NP) | HAEI800933 | Q4QM09 | Similar to: HI0899, DYR_HAEIN dihydrofolate reductase |
| [B] Haemophilus influenzae (strain PittEE) | HAEIE01318 | A5UDH5 | Dihydrofolate reductase |
| [B] Haemophilus influenzae (strain PittGG) | HAEIG01318 | A5UI43 | Dihydrofolate reductase |
| [B] Haemophilus somnus (strain 129PT) | HAES100192 | Q0I1V5 | Dihydrofolate reductase |
| [B] Haemophilus somnus (strain 2336) | HAES200057 | B0UV15 | Dihydrofolate reductase |
| [B] Mannheimia succiniciproducens (strain MBEL55E) | MANSM01850 | Q65RE5 | Dihydrofolate reductase FolA protein |
| [B] Pasteurella multocida | PASMU01893 | Q9CJU8 | FolA |
| [B] Acinetobacter baumannii (strain AB0057) | ACIB500517 | B7I4T9 | Dihydrofolate reductase |
| [B] Acinetobacter baumannii (strain AB307-0294) | ACIB303015 | B7H0P5 | Dihydrofolate reductase type 3(Dihydrofolate reductasetype III) |
| [B] Acinetobacter baumannii (strain ACICU) | ACIBC00465 | B2I3A1 | Dihydrofolate reductase |
| [B] Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) | ACIBT00414 | ABO10912.1 | Dihydrofolate reductase |
| [B] Acinetobacter baumannii (strain AYE) | ACIBY03067 | B0V4P5 | Dihydrofolate reductase |
| [B] Acinetobacter baumannii (strain SDF) | ACIBS02667 | B0VL70 | Dihydrofolate reductase |
| [B] Acinetobacter sp. (strain ADP1) | ACIAD00454 | Q6FER8 | Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme dihydrofolate reductase |
| [B] Cellvibrio japonicus (strain Ueda107) | CELJU00456 | B3PIV8 | Dihydrofolate reductase |
| [B] Pseudomonas aeruginosa (strain PA7) | PSEA700442 | A6UYF3 | Dihydrofolate reductase |
| [B] Pseudomonas entomophila (strain L48) | PSEE400239 | Q1IGG6 | dihydrofolate reductase type I, trimethoprim resistance Evidence 2b : Function of strongly homologous gene; Product type e : enzyme |
| [B] Pseudomonas fluorescens (strain PfO-1) | PSEPF05346 | Q3K556 | Dihydrofolate reductase |
| [B] Pseudomonas mendocina (strain ymp) | PSEMY04150 | A4Y040 | Dihydrofolate reductase |
| [B] Pseudomonas putida (strain W619) | PSEPW00333 | B1J2N5 | Dihydrofolate reductase |
| [B] Pseudomonas syringae (pv. tomato) | PSESM00408 | Q88AF3 | dihydrofolate reductase |
| [B] Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) | PSE1404460 | Q48CM2 | identified by match to protein family HMM PF00186 dihydrofolate reductase |
| [B] Pseudomonas syringae pv. syringae (strain B728a) | PSEU204716 | Q4ZM58 | Dihydrofolate reductase |
| [B] Francisella philomiragia subsp. philomiragia (strain ATCC 25017) | FRAP200579 | B0U102 | Dihydrofolate reductase |
| [B] Francisella tularensis (subsp. tularensis) | FRATT00300 | Q5NHY1 | Similar to Q9K7B6 Dihydrofolate reductase from Bacillus halodurans (163 aa). FASTA: opt: 465 Z-score: 598.3 E(): 2e-25 Smith-Waterman score: 465; 41.566 identity in 166 aa overlap dihydrofolate reductase type I |
| [B] Francisella tularensis subsp. holarctica (strain FTA) | FRATF00163 | A7N9R3 | Dihydrofolate reductase |
| [B] Francisella tularensis subsp. holarctica (strain LVS) | FRATH00192 | Q2A5I3 | dihydrofolate reductase type I |
| [B] Francisella tularensis subsp. holarctica (strain OSU18) | FRATO00156 | Q0BNU0 | Dihydrofolate reductase |
| [B] Francisella tularensis subsp. mediasiatica (strain FSC147) | FRATM01225 | B2SDZ8 | Dihydrofolate reductase |
| [B] Francisella tularensis subsp. novicida (strain U112) | FRATN00224 | A0Q4H0 | dihydrofolate reductase type I |
| [B] Francisella tularensis subsp. tularensis (strain WY96-3418) | FRATW01374 | A4IZU7 | Dihydrofolate reductase |
| [B] Mycobacteriophage FRAT1 | FRAT100299 | Q14JD3 | dihydrofolate reductase type I Similar to Q9K7B6 Dihydrofolate reductase from Bacillus halodurans (163 aa). FASTA: opt: 465 Z-score: 598.3 E(): 2e-25 Smith-Waterman score: 465; 41.566 identity in 166 aa overlap |
| [B] Aliivibrio salmonicida (strain LFI1238) | ALISL00290 | B6EL46 | Dihydrofolate reductase type 3 |
| [B] Vibrio fischeri (strain MJ11) | VIBFM00270 | B5FGG3 | Dihydrofolate reductase |
| [B] Vibrio cholerae | VIBCH00433 | A1ES56 | similar to SP:P12833 PID:150520; identified by sequence similarity; putative dihydrofolate reductase |
| [B] Vibrio cholerae (strain ATCC 39541 / O395) | VIBC302651 | A5F8P5 | Dihydrofolate reductase |
| [B] Vibrio cholerae serotype O1 (strain M66-2) | VIBCM00413 | C3LRH1 | |
| [B] Vibrio fischeri (strain ATCC 700601 / ES114) | VIBF100284 | Q5E867 | dihydrofolate reductase |
| [B] Vibrio harveyi (strain ATCC BAA-1116 / BB120) | VIBHB00681 | A7N0G5 | Putative uncharacterized protein |
| [B] Vibrio parahaemolyticus | VIBPA00333 | A6B5Q2 | similar to GB:AAF93613.1 (AE004131) percent identity 73 in 160 aa dihydrofolate reductase |
| [B] Vibrio splendidus (strain LGP32) | VIBSL00319 | B7VID9 | Dihydrofolate reductase |
| [B] Vibrio vulnificus | VIBVU00627 | Q8DEC9 | COG0262 Dihydrofolate reductase |
| [B] Vibrio vulnificus (strain YJ016) | VIBVY00473 | Q7MP89 | Dihydrofolate reductase |
| [B] Stenotrophomonas maltophilia (strain K279a) | STRMK00760 | B2FPG1 | Putative dihydrofolate reductase |
| [B] Stenotrophomonas maltophilia (strain R551-3) | STRM500663 | B4SK37 | Dihydrofolate reductase |
| [B] Xanthomonas campestris pv. campestris | XANCP00774 | Q8PCE6 | Dihydrofolate reductase type III |
| [B] Xanthomonas campestris pv. campestris (strain 8004) | XANC803342 | Q4UR36 | dihydrofolate reductase type III |
| [B] Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) | VESOH00881 | A5CVJ7 | Dihydrofolate reductase |