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Keyword Protein Sequence Group Entry

OMA Group 189830

Dihydrofolate reductase
This group has 236 members: 2 [E]ukaryota 3 [A]rchaea 231 [B]acteria
Fingerprint: LAHFKRT

Protein List | Alignment | Close Groups | Phyletic Profile | Ontology Download: download fasta, download darwin

[E] Homo sapiensHUMAN06130  UniProtKB/Swiss-Prot DYR_HUMAN   -
[E] Pan troglodytesPANTR05121  Ensembl ENSPTRP00000029175   -
[A] Haloquadratum walsbyi (strain DSM 16790)HALWD01519  UniProtKB/TrEMBL Q18HG9  dihydrofolate reductase
[A] Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)HALLT02121  UniProtKB/TrEMBL B9LR90  Dihydrofolate reductase region
[A] Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)NATPD01451  UniProtKB/TrEMBL Q3IQP3  dihydrofolate reductase (EC 1.5.1.3)
[B] Rhodococcus erythropolis (strain PR4 / NBRC 100887)RHOE404452  UniProtKB/TrEMBL C0ZMB2  Dihydrofolate reductase
[B] Rhodococcus opacus (strain B4)RHOOB01962  UniProtKB/TrEMBL C1B0L0  Dihydrofolate reductase
[B] Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)KINRD04397  UniProtKB/TrEMBL A6WGF8  Dihydrofolate reductase
[B] Leifsonia xyli (subsp. xyli)LEIXX00745  UniProtKB/TrEMBL Q6AFI1  identified by sequence similarity dihydrofolate reductase
[B] Symbiobacterium thermophilumSYMTH03064  UniProtKB/TrEMBL Q67JQ2  dihydrofolate reductase
[B] Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154)BACV801820  UniProtKB/TrEMBL A6L1Q7  Dihydrofolate reductase
[B] Porphyromonas gingivalisPORGI01717  UniProtKB/TrEMBL Q7MTB4  similar to GB:X63753, GB:S47238, GB:S47239, GB:S47240, GB:S79056, SP:P18583, PID:338290, and PID:36546; identified by sequence similarity; putative dihydrofolate reductase
[B] Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257)PORG301991  UniProtKB/TrEMBL B2RMI4  Probable dihydrofolate reductase
[B] Amoebophilus asiaticus (strain 5a2)AMOA500268  UniProtKB/TrEMBL B3ER85  Putative uncharacterized protein
[B] Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101)FLAJ101462  UniProtKB/TrEMBL A5FJX2  Dihydrofolate reductase
[B] Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)FLAPJ00320  UniProtKB/TrEMBL A6GWG8  Dihydrofolate reductase
[B] Gramella forsetii (strain KT0803)GRAFK00274  UniProtKB/TrEMBL A0LY20  dihydrofolate reductase
[B] Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)CYTH301544  UniProtKB/TrEMBL Q11US6  dihydrofolate reductase type I; trimethoprim resistance
[B] Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923)DEIDV02538  UniProtKB/TrEMBL C1D068  Putative dihydrofolate reductase
[B] Deinococcus radioduransDEIRA02558  UniProtKB/TrEMBL Q9RR65  Dihydrofolate reductase
[B] Bacillus amyloliquefaciens (strain FZB42)BACA201909  UniProtKB/TrEMBL A7Z5T2  DfrA
[B] Bacillus anthracisBACAN02050  UniProtKB/TrEMBL B0AVP0  similar to SP:P11045, GB:M99701, and PID:521207; identified by sequence similarity; putative dihydrofolate reductase
[B] Bacillus cereus (strain AH187)BACC702160  UniProtKB/TrEMBL B7HQ33  Dihydrofolate reductase
[B] Bacillus cereus (strain ATCC 10987)BACC102241  UniProtKB/TrEMBL Q738X6  identified by match to protein family HMM PF00186 dihydrofolate reductase
[B] Bacillus cereus (strain ATCC 14579 / DSM 31)BACCR02044  UniProtKB/TrEMBL Q81E04  Dihydrofolate reductase
[B] Bacillus cereus (strain G9842)BACC202061  UniProtKB/TrEMBL B7IV73  Dihydrofolate reductase
[B] Bacillus cereus (strain ZK)BACCZ01994  UniProtKB/TrEMBL Q63BV4  dihydrofolate reductase
[B] Bacillus cereus subsp. cytotoxis (strain NVH 391-98)BACCN01573  UniProtKB/TrEMBL A7GP91  Dihydrofolate reductase
[B] Bacillus haloduransBACHD03392  UniProtKB/TrEMBL Q9K7B6  dihydrofolate reductase
[B] Bacillus licheniformis (strain DSM 13 / ATCC 14580)BACLD02192  UniProtKB/TrEMBL Q65IB5  InterProMatches:IPR001796; glycine/purine/DNA precursor synthesis, conversion of dUMP to dTMP,Molecular Function: dihydrofolate reductase activity (GO:0004146), Biological Process: glycine biosynthesis (GO:0006545), Biological Process: nucleotide biosynthesis (GO:0009165) dihydrofolate reductase
[B] Bacillus pumilus (strain SAFR-032)BACP201880  UniProtKB/TrEMBL A8FEB8  Dihydrofolate reductase
[B] Bacillus subtilisBACSU02180  UniProtKB/Swiss-Prot DYR_BACSU  Dihydrofolate reductase
[B] Bacillus thuringiensis (strain Al Hakam)BACAH01887  UniProtKB/TrEMBL A0RDM0  dihydrofolate reductase
[B] Bacillus thuringiensis (subsp. konkukian)BACHK01979  UniProtKB/TrEMBL Q6HJC6  dihydrofolate reductase
[B] Bacillus weihenstephanensis (strain KBAB4)BACWK02018  UniProtKB/TrEMBL A9VTX1  Dihydrofolate reductase
[B] Geobacillus kaustophilusGEOKA01759  UniProtKB/TrEMBL Q5KZ26  dihydrofolate reductase
[B] Geobacillus thermodenitrificans (strain NG80-2)GEOTN01629  UniProtKB/TrEMBL A4INY0  Dihydrofolate reductase
[B] Lysinibacillus sphaericus (strain C3-41)LYSSC02616  UniProtKB/TrEMBL B1HZG5  Dihydrofolate reductase type 3
[B] Listeria monocytogenesLISMO01869  UniProtKB/TrEMBL C8JS20  similar to dihydrofolate reductases
[B] Listeria monocytogenes (serotype 4b / strain F2365)LISMF01881  UniProtKB/TrEMBL Q71YE2  identified by match to protein family HMM PF00186 dihydrofolate reductase
[B] Listeria monocytogenes serotype 4a (strain HCC23)LISMH00671  UniProtKB/TrEMBL B8DDM9  Dihydrofolate reductase
[B] Listeria monocytogenes serotype 4b (strain Clip81459)LISMC01858  UniProtKB/TrEMBL C1KWH3  Putative dihydrofolate reductase
[B] Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)LISW601891  UniProtKB/TrEMBL A0AJX9  DfrA protein
[B] Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)BREBN04325  UniProtKB/TrEMBL C0ZI90  Dihydrofolate reductase
[B] Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)CLOB804852  UniProtKB/TrEMBL A6M379  Dihydrofolate reductase
[B] Clostridium botulinum (strain Alaska E43 / type E3)CLOBA03125  UniProtKB/TrEMBL B2V0W4  Dihydrofolate reductase
[B] Clostridium botulinum (strain Eklund 17B / type B)CLOBB03356  UniProtKB/TrEMBL B2TR57  Dihydrofolate reductase
[B] Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)CLOCE01251  UniProtKB/TrEMBL B8I0T9  dihydrofolate reductase region PFAM: dihydrofolate reductase region; KEGG: gtn:GTNG_1670 dihydrofolate reductase
[B] Clostridium novyi (strain NT)CLONN00315  UniProtKB/TrEMBL A0PY39  dihydrofolate reductase identified by match to protein family HMM PF00186
[B] Clostridium perfringensCLOPE00044  UniProtKB/TrEMBL Q8XPC1  Probable dihydrofolate reductase
[B] Clostridium perfringens (strain ATCC 13124 / NCTC 8237)CLOP100042  UniProtKB/TrEMBL Q0TV23  dihydrofolate reductase identified by similarity to SP:P11045; match to protein family HMM PF00186
[B] Clostridium perfringens (strain SM101)CLOPS00045  UniProtKB/TrEMBL Q0SWS9  dihydrofolate reductase identified by match to protein family HMM PF00186
[B] Enterococcus faecalisENTFA01469  UniProtKB/TrEMBL C0X5G6  Dihydrofolate reductase
[B] Lactobacillus plantarumLACPL01559  UniProtKB/TrEMBL C2FIE9  dihydrofolate reductase
[B] Leuconostoc citreum (strain KM20)LEUCK00687  UniProtKB/TrEMBL B1MYC2  Dihydrofolate reductase
[B] Caulobacter crescentusCAUCR02095  UniProtKB/TrEMBL Q9A6G8  Dihydrofolate reductase
[B] Caulobacter sp. (strain K31)CAUSK03324  UniProtKB/TrEMBL B0T4Y7  Dihydrofolate reductase precursor
[B] Phenylobacterium zucineum (strain HLK1)PHEZH00817  UniProtKB/TrEMBL B4RGA7  Dihydrofolate reductase
[B] Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)BRASB05685  UniProtKB/TrEMBL A5EPD1  Dihydrofolate reductase
[B] Bradyrhizobium sp. (strain ORS278)BRASO05259  UniProtKB/TrEMBL A4YZC2  Dihydrofolate reductase
[B] Nitrobacter hamburgensis (strain X14 / DSM 10229)NITHX02569  UniProtKB/TrEMBL Q1QJT9  Dihydrofolate reductase
[B] Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391)NITWN02217  UniProtKB/TrEMBL Q3SQ37  dihydrofolate reductase region
[B] Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)OLICO01257  UniProtKB/TrEMBL B6JB68  Dihydrofolate reductase
[B] Rhodopseudomonas palustris (strain BisA53)RHOP502146  UniProtKB/TrEMBL Q07PL3  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: rpc:RPC_3263 dihydrofolate reductase
[B] Rhodopseudomonas palustris (strain BisB5)RHOPS03330  UniProtKB/TrEMBL Q134B2  Dihydrofolate reductase
[B] Brucella abortusBRUAB01293  UniProtKB/TrEMBL C4IS81  similar to BR1398, dihydrofolate reductase FolA, dihydrofolate reductase
[B] Brucella abortus (strain 2308)BRUA201403  UniProtKB/TrEMBL Q2YS23  Dihydrofolate reductase
[B] Brucella abortus (strain S19)BRUA101250  UniProtKB/TrEMBL B2S6M2  Dihydrofolate reductase
[B] Brucella canis (strain ATCC 23365 / NCTC 10854)BRUC201345  UniProtKB/TrEMBL A9M656  Dihydrofolate reductase type 3
[B] Brucella melitensisBRUME00607  UniProtKB/TrEMBL D0B8M8  DIHYDROFOLATE REDUCTASE
[B] Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)BRUO201202  UniProtKB/TrEMBL A5VRE6  Dihydrofolate reductase
[B] Brucella suisBRUSU01345  UniProtKB/TrEMBL Q8FZS4  identified by match to PFAM protein family HMM PF00186 dihydrofolate reductase
[B] Brucella suis (strain ATCC 23445 / NCTC 10510)BRUSI01361  UniProtKB/TrEMBL B0CHI6  Dihydrofolate reductase type 3 GO_function: dihydrofolate reductase activity [GO ID 0004146]; GO_process: glycine biosynthetic process [GO ID 0006545]
[B] Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)OCHA401768  UniProtKB/TrEMBL A6WZV5  Dihydrofolate reductase
[B] Methylobacterium nodulans (strain ORS2060 / LMG 21967)METNO00662  UniProtKB/TrEMBL B8IF21  Dihydrofolate reductase region
[B] Mesorhizobium sp. (strain BNC1)MESSB01739  UniProtKB/TrEMBL Q11HI1  dihydrofolate reductase region PFAM: dihydrofolate reductase region KEGG: bmb:BruAb1_1393 FolA, dihydrofolate reductase
[B] Rhizobium lotiRHILO01144  UniProtKB/TrEMBL Q98KI7  dihydrofolate reductase
[B] Agrobacterium radiobacter (strain K84 / ATCC BAA-868)AGRRK02184  UniProtKB/TrEMBL B9JGK8  Dihydrofolate reductase protein
[B] Agrobacterium tumefaciens (strain C58 / ATCC 33970)AGRT501995  UniProtKB/TrEMBL A9CIC8  Dihydrofolate reductase
[B] Rhizobium melilotiRHIME02102  UniProtKB/TrEMBL Q92NQ7  Product confidence : probable Gene name confidence : probable predicted by Codon_usage predicted by Homology predicted by FrameD PROBABLE DIHYDROFOLATE REDUCTASE PROTEIN
[B] Sinorhizobium medicae (strain WSM419)SINMW01970  UniProtKB/TrEMBL A6UB22  Dihydrofolate reductase
[B] Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)XANP201365  UniProtKB/TrEMBL A7IF75  Dihydrofolate reductase
[B] Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)RHOS401993  UniProtKB/TrEMBL Q3J0X0  Dihydrofolate reductase
[B] Rhodobacter sphaeroides (strain KD131 / KCTC 12085)RHOSK01698  UniProtKB/TrEMBL B9KKD1  Dihydrofolate reductase
[B] Roseobacter denitrificans (strain ATCC 33942 / OCh 114)ROSDO01740  UniProtKB/TrEMBL Q168V7  dihydrofolate reductase
[B] Silicibacter sp. (strain TM1040)SILST01720  UniProtKB/TrEMBL Q1GFV5  Dihydrofolate reductase PFAM: dihydrofolate reductase region: (5.1e-44) KEGG: rsp:RSP_0389 dihydrofolate reductase, ev=3e-49, 59% identity
[B] Bordetella avium (strain 197N)BORA100495  UniProtKB/TrEMBL Q2KYI7  dihydrofolate reductase
[B] Bordetella bronchisepticaBORBR00866  UniProtKB/TrEMBL Q7WP14  ortholog of Bordetella pertussis (BX470248) BP3155 dihydrofolate reductase
[B] Bordetella parapertussisBORPA00780  UniProtKB/TrEMBL Q7W1B0  ortholog of Bordetella pertussis (BX470248) BP3155 dihydrofolate reductase
[B] Bordetella pertussisBORPE02889  UniProtKB/TrEMBL Q7VUE2  Similar to Escherichia coli dihydrofolate reductase FolA or TmrA or B0048 SW:DYR_ECOLI (P00379) (159 aa) fasta scores: E(): 1.9e-23, 46.54% id in 159 aa, and to Salmonella typhimurium dihydrofolate reductase type III DhfrIII SW:DYR3_SALTY (P12833) (162 aa) fasta scores: E(): 3.6e-25, 47.17% id in 159 aa dihydrofolate reductase
[B] Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)BORPD03960  UniProtKB/TrEMBL A9I779  FolA protein
[B] Burkholderia ambifaria (strain MC40-6)BURA400948  UniProtKB/TrEMBL B1YV70  Dihydrofolate reductase
[B] Burkholderia cenocepacia (strain AU 1054)BURCA00596  UniProtKB/TrEMBL Q1BXZ1  Dihydrofolate reductase
[B] Burkholderia cenocepacia (strain HI2424)BURCH01074  UniProtKB/TrEMBL A0K5Q8  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: bcn:Bcen_0603 dihydrofolate reductase
[B] Burkholderia cenocepacia (strain MC0-3)BURCC01033  UniProtKB/TrEMBL B1JXV6  Dihydrofolate reductase
[B] Burkholderia cepacia (strain ATCC 53795 / AMMD)BURCM00953  UniProtKB/TrEMBL Q0BH56  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: bur:Bcep18194_A4196 dihydrofolate reductase
[B] Burkholderia cepacia (strain J2315 / LMG 16656)BURCJ02792  UniProtKB/TrEMBL B4EAM3  dihydrofolate reductase CDS is associated with trimethoprim resistance
[B] Burkholderia sp. (strain 383)BURS301008  UniProtKB/TrEMBL Q39IC3  Dihydrofolate reductase
[B] Burkholderia vietnamiensis (strain G4 / LMG 22486)BURVG00970  UniProtKB/TrEMBL A4JCL0  Dihydrofolate reductase
[B] Burkholderia malleiBURMA00325  UniProtKB/TrEMBL A5JCE2  Dihydrofolate reductase
[B] Burkholderia mallei (strain NCTC 10229)BURM900852  UniProtKB/TrEMBL A2S4M4  Dihydrofolate reductase
[B] Burkholderia mallei (strain NCTC 10247)BURM700221  UniProtKB/TrEMBL A3MHT3  Dihydrofolate reductase
[B] Burkholderia mallei (strain SAVP1)BURMS02378  UniProtKB/TrEMBL A1V6H9  Dihydrofolate reductase
[B] Burkholderia phymatum (strain DSM 17167 / STM815)BURP800773  UniProtKB/TrEMBL B2JF42  Dihydrofolate reductase
[B] Burkholderia phytofirmans (strain DSM 17436 / PsJN)BURPP02882  UniProtKB/TrEMBL B2T5Z4  Dihydrofolate reductase
[B] Burkholderia pseudomalleiBURPS02485  UniProtKB/TrEMBL A4LE85  Similar to Escherichia coli dihydrofolate reductase FolA or TmrA or b0048 SWALL:DYR_ECOLI (SWALL:P00379) (159 aa) fasta scores: E(): 4e-22, 45.34% id in 161 aa, and to Ralstonia solanacearum probable dihydrofolate reductase oxidoreductase protein rsc0946 or rs04449 SWALL:Q8Y0U7 (EMBL:AL646061) (167 aa) fasta scores: E(): 1.2e-42, 72.39% id in 163 aa dihydrofolate reductase
[B] Burkholderia pseudomallei (strain 1106a)BURP002847  UniProtKB/TrEMBL A3NXS6  Dihydrofolate reductase
[B] Burkholderia pseudomallei (strain 1710b)BURP102890  UniProtKB/TrEMBL Q3JQ22  dihydrofolate reductase identified by match to protein family HMM PF00186
[B] Burkholderia pseudomallei (strain 668)BURP602803  UniProtKB/TrEMBL A3NBZ0  Dihydrofolate reductase
[B] Burkholderia xenovorans (strain LB400)BURXL03300  UniProtKB/TrEMBL Q13VG2  Dihydrofolate reductase
[B] Cupriavidus taiwanensis (strain R1 / LMG 19424)CUPTR02138  UniProtKB/TrEMBL B3R5A7  Dihydrofolate reductase type I
[B] Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)RALEH02627  UniProtKB/TrEMBL Q0K888  dihydrofolate reductase
[B] Ralstonia eutropha (strain JMP134)RALEJ00908  UniProtKB/TrEMBL Q473Z0  Dihydrofolate reductase
[B] Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)RALME02520  UniProtKB/TrEMBL Q1LK80  dihydrofolate reductase region
[B] Polynucleobacter necessarius (strain STIR1)POLNS00335  UniProtKB/TrEMBL B1XTJ0  Dihydrofolate reductase
[B] Polynucleobacter sp. (strain QLW-P1DMWA-1)POLSQ00375  UniProtKB/TrEMBL A4SVT6  Dihydrofolate reductase
[B] Ralstonia pickettii (strain 12J)RALPJ00796  UniProtKB/TrEMBL B2U8M3  Dihydrofolate reductase
[B] Ralstonia solanacearumRALSO00942  UniProtKB/TrEMBL Q8Y0U7  Product confidence : probable Gene name confidence : putative predicted by Codon_usage predicted by Homology predicted by FrameD PROBABLE DIHYDROFOLATE REDUCTASE OXIDOREDUCTASE PROTEIN
[B] Acidovorax avenae subsp. citrulli (strain AAC00-1)ACIAC01384  UniProtKB/TrEMBL A1TM51  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: rfr:Rfer_2985 dihydrofolate reductase
[B] Acidovorax sp. (strain JS42)ACISJ01148  UniProtKB/TrEMBL A1W5A2  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: pol:Bpro_1822 dihydrofolate reductase
[B] Diaphorobacter sp. (strain TPSY)DIAST01097  UniProtKB/TrEMBL B9MG01  Dihydrofolate reductase
[B] Polaromonas naphthalenivorans (strain CJ2)POLNA02712  UniProtKB/TrEMBL A1VQZ7  Dihydrofolate reductase
[B] Polaromonas sp. (strain JS666 / ATCC BAA-500)POLSJ01781  UniProtKB/TrEMBL Q12CI7  Dihydrofolate reductase
[B] Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)RHOFD02918  UniProtKB/TrEMBL Q21U57  Dihydrofolate reductase
[B] Verminephrobacter eiseniae (strain EF01-2)VEREI03083  UniProtKB/TrEMBL A1WMP6  Dihydrofolate reductase
[B] Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6)LEPCP01245  UniProtKB/TrEMBL B1Y5E0  Dihydrofolate reductase
[B] Methylibium petroleiphilum (strain PM1)METPP02012  UniProtKB/TrEMBL A2SHH1  Dihydrofolate reductase
[B] Herminiimonas arsenicoxydansHERAR00990  UniProtKB/TrEMBL A4G3Z7  Dihydrofolate reductase
[B] Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis)JANMA01191  UniProtKB/TrEMBL A6SX85  Dihydrofolate reductase
[B] Thiobacillus denitrificans (strain ATCC 25259)THIDA02038  UniProtKB/TrEMBL Q3SH97  dihydrofolate reductase
[B] Methylobacillus flagellatus (strain KT / ATTC 51484 / DSM 6875)METFK00910  UniProtKB/TrEMBL Q1H2G1  Dihydrofolate reductase
[B] Chromobacterium violaceumCHRVO01028  UniProtKB/TrEMBL Q7NZ94  identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0262 dihydrofolate reductase
[B] Laribacter hongkongensis (strain HLHK9)LARHH00762  UniProtKB/TrEMBL C1D4I6  Dihydrofolate reductase
[B] Neisseria meningitidis serogroup C (strain 053442)NEIM001730  UniProtKB/TrEMBL A9M313  dihydrofolate reductase Code: H; COG: COG0262
[B] Nitrosomonas europaeaNITEU00545  UniProtKB/TrEMBL Q82WU4  Dihydrofolate reductase
[B] Nitrosomonas eutropha (strain C71)NITEC00957  UniProtKB/TrEMBL Q0AHA5  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: neu:NE0567 dihydrofolate reductase
[B] Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849)NITMU01887  UniProtKB/TrEMBL Q2Y7L3  Dihydrofolate reductase
[B] Azoarcus sp. (strain BH72)AZOSB03187  UniProtKB/TrEMBL A1KAF8  FolA protein Dihydrofolate reductase. catalytic activity: 5,6,7,8-tetrahydrofolate + nadp(+) = 7,8- dihydrofolate + nadph. pathway: essential step for de novo glycine and purine synthesis, dna precursor synthesis, and for the conversion of dump to dtmp. Pfam: Dihydrofolate reductase High confidence in function and specificity
[B] Azoarcus sp. (strain EbN1)AZOSE02440  UniProtKB/TrEMBL Q5P234  Dihydrofolate reductase
[B] Dechloromonas aromatica (strain RCB)DECAR00574  UniProtKB/TrEMBL Q47IJ5  Dihydrofolate reductase region
[B] Bdellovibrio bacteriovorusBDEBA02961  UniProtKB/TrEMBL Q6MID1  InterPro: Dihydrofolate reductase hypothetical protein
[B] Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)GEOMG02853  UniProtKB/TrEMBL Q39RF9  Dihydrofolate reductase region
[B] Geobacter sulfurreducensGEOSL00561  UniProtKB/TrEMBL Q74FN5  Dihydrofolate reductase
[B] Geobacter uraniumreducens (strain Rf4)GEOUR00889  UniProtKB/TrEMBL A5GBA2  Dihydrofolate reductase
[B] Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)PELCD02915  UniProtKB/TrEMBL Q3A0W8  Dihydrofolate reductase
[B] Myxococcus xanthus (strain DK 1622)MYXXD05712  UniProtKB/TrEMBL Q1CZU3  dihydrofolate reductase identified by similarity to SP:P11045; match to protein family HMM PF00186
[B] Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)AERHH03283  UniProtKB/TrEMBL A0KNL5  dihydrofolate reductase identified by similarity to SP:P00379; match to protein family HMM PF00186
[B] Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)MARAV02324  UniProtKB/TrEMBL A1U3D7  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: abo:ABO_2343 dihydrofolate reductase
[B] Colwellia psychrerythraea (strain 34H / ATCC BAA-681)COLP304330  UniProtKB/TrEMBL Q47VL9  identified by similarity to SP:P00379; match to protein family HMM PF00186 dihydrofolate reductase
[B] Idiomarina loihiensisIDILO00476  UniProtKB/TrEMBL Q5R038  Dihydrofolate reductase
[B] Psychromonas ingrahamii (strain 37)PSYIN01009  UniProtKB/TrEMBL A1STR9  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: ilo:IL0478 dihydrofolate reductase
[B] Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)SHEAM02808  UniProtKB/TrEMBL A1S9H0  Dihydrofolate reductase KEGG: son:SO3646 dihydrofolate reductase
[B] Shewanella baltica (strain OS155 / ATCC BAA-1091)SHEB500935  UniProtKB/TrEMBL A3D183  Dihydrofolate reductase
[B] Shewanella baltica (strain OS185)SHEB801012  UniProtKB/TrEMBL A6WK54  Dihydrofolate reductase
[B] Shewanella baltica (strain OS195)SHEB901061  UniProtKB/TrEMBL A9L433  PFAM: dihydrofolate reductase region KEGG: shw:Sputw3181_3183 dihydrofolate reductase Dihydrofolate reductase
[B] Shewanella baltica (strain OS223)SHEB203218  UniProtKB/TrEMBL B8EC01  Dihydrofolate reductase
[B] Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)SHEDO02876  UniProtKB/TrEMBL Q12K26  Dihydrofolate reductase
[B] Shewanella frigidimarina (strain NCIMB 400)SHEFN03030  UniProtKB/TrEMBL Q07YJ3  Dihydrofolate reductase
[B] Shewanella loihica (strain BAA-1088 / PV-4)SHELP00873  UniProtKB/TrEMBL A3QB98  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: son:SO3646 dihydrofolate reductase
[B] Shewanella oneidensisSHEON03406  UniProtKB/TrEMBL Q8EB86  Dihydrofolate reductase
[B] Shewanella pealeana (strain ANG-SQ1 / ATCC 700345)SHEPA00839  UniProtKB/TrEMBL A8H0U7  PFAM: dihydrofolate reductase region KEGG: shm:Shewmr7_3120 dihydrofolate reductase Dihydrofolate reductase
[B] Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)SHEPC00958  UniProtKB/TrEMBL A4Y430  Dihydrofolate reductase
[B] Shewanella sediminis (strain HAW-EB3)SHESH00955  UniProtKB/TrEMBL A8FRU7  KEGG: slo:Shew_0874 dihydrofolate reductase Dihydrofolate reductase
[B] Shewanella sp. (strain ANA-3)SHESA03175  UniProtKB/TrEMBL A0L069  dihydrofolate reductase region PFAM: dihydrofolate reductase region KEGG: son:SO3646 dihydrofolate reductase
[B] Shewanella sp. (strain MR-4)SHESM00896  UniProtKB/TrEMBL Q0HLT7  Dihydrofolate reductase
[B] Shewanella sp. (strain MR-7)SHESR03088  UniProtKB/TrEMBL Q0HS01  Dihydrofolate reductase
[B] Shewanella sp. (strain W3-18-1)SHESW03112  UniProtKB/TrEMBL A1RMV3  Dihydrofolate reductase PFAM: dihydrofolate reductase region KEGG: shm:Shewmr7_3120 dihydrofolate reductase
[B] Shewanella woodyi (strain ATCC 51908 / MS32)SHEWM00998  UniProtKB/TrEMBL B1KGH4  Dihydrofolate reductase
[B] Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)NITOC00207  UniProtKB/TrEMBL Q3JEI1  Dihydrofolate reductase
[B] Alkalilimnicola ehrlichei (strain MLHE-1)ALHEH00418  UniProtKB/TrEMBL Q0ABL0  Dihydrofolate reductase
[B] Thioalkalivibrio sp. (strain HL-EbGR7)THISH02707  UniProtKB/TrEMBL B8GN07  Dihydrofolate reductase
[B] Buchnera aphidicola (subsp. Acyrthosiphon pisum)BUCAI00133  UniProtKB/Swiss-Prot DYR_BUCAI  dihydrofolate reductase
[B] Buchnera aphidicola (subsp. Baizongia pistaciae)BUCBP00123  UniProtKB/Swiss-Prot DYR_BUCBP  COG0262 dihydrofolate reductase
[B] Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)BUCA500129  UniProtKB/TrEMBL B8D8U4  Dihydrofolate reductase
[B] Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)BUCAT00129  UniProtKB/TrEMBL B8D748  Dihydrofolate reductase
[B] Erwinia tasmaniensis (strain DSM 17950 / ET1/99)ERWT900721  UniProtKB/TrEMBL B2VGQ7  Dihydrofolate reductase
[B] Erwinia carotovora (subsp. atroseptica)ERWCT03829  UniProtKB/TrEMBL Q6D0D5  Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri dihydrofolate reductase FolA or TmrA or b0048 or c0058 or sf0045 SWALL:DYR_ECOLI (SWALL:P00379) (159 aa) fasta scores: E(): 9e-51, 79.24% id in 159 aa dihydrofolate reductase
[B] Wigglesworthia glossinidia brevipalpisWIGBR00022  UniProtKB/TrEMBL Q8D3H9  Biosynthesis of cofactors, prosthetic groups, and carrier
[B] Blochmannia pennsylvanicus (strain BPEN)BLOPB00119  UniProtKB/TrEMBL Q494F1  ortholog to Escherichia coli bnum: b0048; MultiFun: Metabolism 1.5.3.2, 1.7.17 dihydrofolate reductase type I
[B] Coxiella burnetiiCOXBU01887  UniProtKB/TrEMBL A9ZG78  similar to GB:X63753, GB:S47238, GB:S47239, GB:S47240, GB:S79056, SP:P18583, PID:338290, PID:36546, GB:X63753, GB:S47238, GB:S47239, GB:S47240, GB:S79056, SP:P18583, PID:338290, and PID:36546; identified by sequence similarity; putative dihydrofolate reductase
[B] Coxiella burnetii (strain CbuG_Q212)COXB201739  UniProtKB/TrEMBL B6J3B8  Dihydrofolate reductase
[B] Coxiella burnetii (strain Dugway 5J108-111)COXBN01944  UniProtKB/TrEMBL A9KH09  Dihydrofolate reductase
[B] Coxiella burnetii (strain RSA 331 / Henzerling II)COXBR00084  UniProtKB/TrEMBL A9N9I0  Dihydrofolate reductase
[B] Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)ALCBS02341  UniProtKB/TrEMBL Q0VM07  Dihydrofolate reductase
[B] Hahella chejuensis (strain KCTC 2396)HAHCH05519  UniProtKB/TrEMBL Q2SA18  Dihydrofolate reductase COG0262
[B] Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)CHRSD02553  UniProtKB/TrEMBL Q1QUE0  Dihydrofolate reductase
[B] Marinomonas sp. (strain MWYL1)MARMS03675  UniProtKB/TrEMBL A6W1R3  Dihydrofolate reductase
[B] Haemophilus influenzaeHAEIN00884  UniProtKB/Swiss-Prot DYR_HAEIN  Dihydrofolate reductase
[B] Haemophilus influenzae (strain 86-028NP)HAEI800933  UniProtKB/TrEMBL Q4QM09  Similar to: HI0899, DYR_HAEIN dihydrofolate reductase
[B] Haemophilus influenzae (strain PittEE)HAEIE01318  UniProtKB/TrEMBL A5UDH5  Dihydrofolate reductase
[B] Haemophilus influenzae (strain PittGG)HAEIG01318  UniProtKB/TrEMBL A5UI43  Dihydrofolate reductase
[B] Haemophilus somnus (strain 129PT)HAES100192  UniProtKB/TrEMBL Q0I1V5  Dihydrofolate reductase
[B] Haemophilus somnus (strain 2336)HAES200057  UniProtKB/TrEMBL B0UV15  Dihydrofolate reductase
[B] Mannheimia succiniciproducens (strain MBEL55E)MANSM01850  UniProtKB/TrEMBL Q65RE5  Dihydrofolate reductase FolA protein
[B] Pasteurella multocidaPASMU01893  UniProtKB/TrEMBL Q9CJU8  FolA
[B] Acinetobacter baumannii (strain AB0057)ACIB500517  UniProtKB/TrEMBL B7I4T9  Dihydrofolate reductase
[B] Acinetobacter baumannii (strain AB307-0294)ACIB303015  UniProtKB/TrEMBL B7H0P5  Dihydrofolate reductase type 3(Dihydrofolate reductasetype III)
[B] Acinetobacter baumannii (strain ACICU)ACIBC00465  UniProtKB/TrEMBL B2I3A1  Dihydrofolate reductase
[B] Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755)ACIBT00414   ABO10912.1  Dihydrofolate reductase
[B] Acinetobacter baumannii (strain AYE)ACIBY03067  UniProtKB/TrEMBL B0V4P5  Dihydrofolate reductase
[B] Acinetobacter baumannii (strain SDF)ACIBS02667  UniProtKB/TrEMBL B0VL70  Dihydrofolate reductase
[B] Acinetobacter sp. (strain ADP1)ACIAD00454  UniProtKB/TrEMBL Q6FER8  Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme dihydrofolate reductase
[B] Cellvibrio japonicus (strain Ueda107)CELJU00456  UniProtKB/TrEMBL B3PIV8  Dihydrofolate reductase
[B] Pseudomonas aeruginosa (strain PA7)PSEA700442  UniProtKB/TrEMBL A6UYF3  Dihydrofolate reductase
[B] Pseudomonas entomophila (strain L48)PSEE400239  UniProtKB/TrEMBL Q1IGG6  dihydrofolate reductase type I, trimethoprim resistance Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
[B] Pseudomonas fluorescens (strain PfO-1)PSEPF05346  UniProtKB/TrEMBL Q3K556  Dihydrofolate reductase
[B] Pseudomonas mendocina (strain ymp)PSEMY04150  UniProtKB/TrEMBL A4Y040  Dihydrofolate reductase
[B] Pseudomonas putida (strain W619)PSEPW00333  UniProtKB/TrEMBL B1J2N5  Dihydrofolate reductase
[B] Pseudomonas syringae (pv. tomato)PSESM00408  UniProtKB/TrEMBL Q88AF3  dihydrofolate reductase
[B] Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)PSE1404460  UniProtKB/TrEMBL Q48CM2  identified by match to protein family HMM PF00186 dihydrofolate reductase
[B] Pseudomonas syringae pv. syringae (strain B728a)PSEU204716  UniProtKB/TrEMBL Q4ZM58  Dihydrofolate reductase
[B] Francisella philomiragia subsp. philomiragia (strain ATCC 25017)FRAP200579  UniProtKB/TrEMBL B0U102  Dihydrofolate reductase
[B] Francisella tularensis (subsp. tularensis)FRATT00300  UniProtKB/TrEMBL Q5NHY1  Similar to Q9K7B6 Dihydrofolate reductase from Bacillus halodurans (163 aa). FASTA: opt: 465 Z-score: 598.3 E(): 2e-25 Smith-Waterman score: 465; 41.566 identity in 166 aa overlap dihydrofolate reductase type I
[B] Francisella tularensis subsp. holarctica (strain FTA)FRATF00163  UniProtKB/TrEMBL A7N9R3  Dihydrofolate reductase
[B] Francisella tularensis subsp. holarctica (strain LVS)FRATH00192  UniProtKB/TrEMBL Q2A5I3  dihydrofolate reductase type I
[B] Francisella tularensis subsp. holarctica (strain OSU18)FRATO00156  UniProtKB/TrEMBL Q0BNU0  Dihydrofolate reductase
[B] Francisella tularensis subsp. mediasiatica (strain FSC147)FRATM01225  UniProtKB/TrEMBL B2SDZ8  Dihydrofolate reductase
[B] Francisella tularensis subsp. novicida (strain U112)FRATN00224  UniProtKB/TrEMBL A0Q4H0  dihydrofolate reductase type I
[B] Francisella tularensis subsp. tularensis (strain WY96-3418)FRATW01374  UniProtKB/TrEMBL A4IZU7  Dihydrofolate reductase
[B] Mycobacteriophage FRAT1FRAT100299  UniProtKB/TrEMBL Q14JD3  dihydrofolate reductase type I Similar to Q9K7B6 Dihydrofolate reductase from Bacillus halodurans (163 aa). FASTA: opt: 465 Z-score: 598.3 E(): 2e-25 Smith-Waterman score: 465; 41.566 identity in 166 aa overlap
[B] Aliivibrio salmonicida (strain LFI1238)ALISL00290  UniProtKB/TrEMBL B6EL46  Dihydrofolate reductase type 3
[B] Vibrio fischeri (strain MJ11)VIBFM00270  UniProtKB/TrEMBL B5FGG3  Dihydrofolate reductase
[B] Vibrio choleraeVIBCH00433  UniProtKB/TrEMBL A1ES56  similar to SP:P12833 PID:150520; identified by sequence similarity; putative dihydrofolate reductase
[B] Vibrio cholerae (strain ATCC 39541 / O395)VIBC302651  UniProtKB/TrEMBL A5F8P5  Dihydrofolate reductase
[B] Vibrio cholerae serotype O1 (strain M66-2)VIBCM00413  UniProtKB/TrEMBL C3LRH1  
[B] Vibrio fischeri (strain ATCC 700601 / ES114)VIBF100284  UniProtKB/TrEMBL Q5E867  dihydrofolate reductase
[B] Vibrio harveyi (strain ATCC BAA-1116 / BB120)VIBHB00681  UniProtKB/TrEMBL A7N0G5  Putative uncharacterized protein
[B] Vibrio parahaemolyticusVIBPA00333  UniProtKB/TrEMBL A6B5Q2  similar to GB:AAF93613.1 (AE004131) percent identity 73 in 160 aa dihydrofolate reductase
[B] Vibrio splendidus (strain LGP32)VIBSL00319  UniProtKB/TrEMBL B7VID9  Dihydrofolate reductase
[B] Vibrio vulnificusVIBVU00627  UniProtKB/TrEMBL Q8DEC9  COG0262 Dihydrofolate reductase
[B] Vibrio vulnificus (strain YJ016)VIBVY00473  UniProtKB/TrEMBL Q7MP89  Dihydrofolate reductase
[B] Stenotrophomonas maltophilia (strain K279a)STRMK00760  UniProtKB/TrEMBL B2FPG1  Putative dihydrofolate reductase
[B] Stenotrophomonas maltophilia (strain R551-3)STRM500663  UniProtKB/TrEMBL B4SK37  Dihydrofolate reductase
[B] Xanthomonas campestris pv. campestrisXANCP00774  UniProtKB/TrEMBL Q8PCE6  Dihydrofolate reductase type III
[B] Xanthomonas campestris pv. campestris (strain 8004)XANC803342  UniProtKB/TrEMBL Q4UR36  dihydrofolate reductase type III
[B] Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)VESOH00881  UniProtKB/TrEMBL A5CVJ7  Dihydrofolate reductase