List of all proteins in the group
Allows comparison of IDs and descriptions
of all proteins in the OMA Group.
Display an MSA of all sequences in the group.
The MSA is created using the Mafft program.
The jalview applet allows for numerous
display and export options.
Display closely related groups
The close groups are made of the set of all
groups that are linked by at least one pair
of orthologs.
Note that not all pairs of proteins coming
from close groups are orthologous. If that
were the case, the two groups would have
been merged.
Display phyletic profile
The "Phyletic profile" displays OMA groups
that have similar patterns of presence/absence
across species. This can be useful to detect
proteins that have complementary function
(e.g. member of the same metabolic pathway).
Compare GO annotations
This function displays a table of all
Gene Ontology (GO) annotations on
proteins of the OMA group. This
allows to compare the annotations
and serves as an additional description
of this OMA group.
OMA fingerprint
The fingerprint is a subsequence that is specific to a
certain group in the current OMA release
Since the group number is specific to a release, this
is the best way to track a group across releases.
OMA

Keyword Protein Sequence Group Entry

OMA Group 53513

KETO ACID DEHYDROGENASE COMPLEX
This group has 13 members: 11 [E]ukaryota 2 [B]acteria
Fingerprint: KEDIDAY

Protein List | Alignment | Close Groups | Phyletic Profile | Ontology Download: download fasta, download darwin

[E] Tarsius syrichtaTARSY11813  Ensembl ENSTSYP00000004416  Lipoamide acyltransferase component of branched- chain alpha-keto acid dehydrogenase complex, mitochondrial Precursor (EC 2.3.1.168)(Dihydrolipoyllysine-residue (2- methylpropanoyl)transferase)(Dihydrolipoamide branched chain transacylase)(BCKAD E2 subunit)(E2) [Source:UniProtKB/Swiss-Prot;Acc:P11182]
[E] Procavia capensisPROCA10191  Ensembl ENSPCAP00000004687  Lipoamide acyltransferase component of branched- chain alpha-keto acid dehydrogenase complex, mitochondrial Precursor (EC 2.3.1.168)(Dihydrolipoyllysine-residue (2- methylpropanoyl)transferase)(Dihydrolipoamide branched chain transacylase)(BCKAD E2 subunit)(E2) [Source:UniProtKB/Swiss-Prot;Acc:P11182]
[E] Canis familiarisCANFA06308  Ensembl ENSCAFP00000029657   -
[E] Monodelphis domesticaMONDO07826  Ensembl ENSMODP00000004387  "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
[E] Oryzias latipesORYLA14143  Ensembl ENSORLP00000004165   -
[E] Drosophila melanogasterDROME13248  UniProtKB/TrEMBL Q9VXY3  CG5599-PA
[E] Caenorhabditis elegansCAEEL04944  UniProtKB/TrEMBL Q23571  ZK669.4 is orthologous to the human gene DIHYDROLIPOAMIDE BRANCHED CHAIN TRANSACYLASE (E2 COMPONENT OF BRANCHED CHAIN KETO ACID DEHYDROGENASE COMPLEX. (DBT), which when mutated leads to maple syrup urine disease, type II (OMIM:248610). the ZK669.4 protein is predicted to be mitochondrial with 68% accuracy.
[E] Nematostella vectensisNEMVE05876  UniProtKB/TrEMBL A7RQN7  jgi|Nemve1|90374|e_gw.23.58.1
[E] Leishmania majorLEIMA07451  UniProtKB/TrEMBL Q4QJI5  LmjF05.0180, predicted protein, len = 477 aa, probably acyltransferase; predicted pI = 8.5485; contains Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme; contains match to PROSITE PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site; contains Pfam match to entry PF02817 e3_binding, e3 binding domain; contains Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain); contains no predicted TM helices; good similarity to lipoamide acyltransferase in other organisms dihydrolipoamide branched chain transacylase, putative
[E] Aspergillus fumigatusASPFU06726  UniProtKB/TrEMBL Q4WQ92  go_component: mitochondrial matrix [goid 0005759]; go_process: tricarboxylic acid cycle [goid 0006099]; go_process: 2-oxoglutarate metabolism [goid 0006103] alpha keto acid dehydrogenase complex, E2 component
[E] Botrytis cinereaBOTFB06852  UniProtKB/TrEMBL A6RRC1  Botrytis cinerea hypothetical protein
[B] Staphylococcus epidermidis (strain ATCC 12228)STAES00775  UniProtKB/Swiss-Prot ODP2_STAES  Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
[B] Staphylococcus epidermidis (strain ATCC 35984 / RP62A)STAEQ00659  UniProtKB/Swiss-Prot ODP2_STAEQ  identified by similarity to EGAD:102440; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817 pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase