List of all proteins in the group
Allows comparison of IDs and descriptions
of all proteins in the OMA Group.
Display an MSA of all sequences in the group.
The MSA is created using the Mafft program.
The jalview applet allows for numerous
display and export options.
Display closely related groups
The close groups are made of the set of all
groups that are linked by at least one pair
of orthologs.
Note that not all pairs of proteins coming
from close groups are orthologous. If that
were the case, the two groups would have
been merged.
Display phyletic profile
The "Phyletic profile" displays OMA groups
that have similar patterns of presence/absence
across species. This can be useful to detect
proteins that have complementary function
(e.g. member of the same metabolic pathway).
Compare GO annotations
This function displays a table of all
Gene Ontology (GO) annotations on
proteins of the OMA group. This
allows to compare the annotations
and serves as an additional description
of this OMA group.
OMA fingerprint
The fingerprint is a subsequence that is specific to a
certain group in the current OMA release
Since the group number is specific to a release, this
is the best way to track a group across releases.
OMA

Keyword Protein Sequence Group Entry

OMA Group 184506

hydroxyacylglutathione hydrolase
This group has 61 members: 58 [E]ukaryota 3 [B]acteria
Fingerprint: GSLNVKC

Protein List | Alignment | Close Groups | Phyletic Profile | Ontology Download: download fasta, download darwin

[E] Homo sapiensHUMAN11639  UniProtKB/Swiss-Prot GLO2_HUMAN   -
[E] Pan troglodytesPANTR14521  Ensembl ENSPTRP00000013008   -
[E] Pongo pygmaeus abeliiPONAB02571  Ensembl ENSPPYP00000007887  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II).
[E] Macaca mulattaMACMU22032  Ensembl ENSMMUP00000000990   -
[E] Microcebus murinusMICMU08601  Ensembl ENSMICP00000001952   -
[E] Otolemur garnettiiOTOGA12925  Ensembl ENSOGAP00000011344   -
[E] Cavia porcellusCAVPO01786  Ensembl ENSCPOP00000020810  Hydroxyacylglutathione hydrolase (EC 3.1.2.6)(Glyoxalase II)(Glx II) [Source:UniProtKB/Swiss- Prot;Acc:Q16775]
[E] Mus musculusMOUSE15010  Ensembl ENSMUSP00000024974  hydroxyacyl glutathione hydrolase
[E] Rattus norvegicusRATNO20739  Ensembl ENSRNOP00000020192  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II) (Round spermatid protein RSP29). [Source:UniProtKB/Swiss-Prot;Acc:O35952]
[E] Canis familiarisCANFA06162  Ensembl ENSCAFP00000028822   -
[E] Felis catusFELCA06663  Ensembl ENSFCAP00000010890   -
[E] Tursiops truncatusTURTR10980  Ensembl ENSTTRP00000010797   -
[E] Bos taurusBOVIN12887  UniProtKB/Swiss-Prot GLO2_BOVIN  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II)
[E] Pteropus vampyrusPTEVA08936  Ensembl ENSPVAP00000015751   -
[E] Myotis lucifugusMYOLU02559  Ensembl ENSMLUP00000000712   -
[E] Equus caballusHORSE19277  Ensembl ENSECAP00000004460  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II).
[E] Monodelphis domesticaMONDO16421  Ensembl ENSMODP00000020125  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (GLX II).
[E] Ornithorhynchus anatinusORNAN15580  Ensembl ENSOANP00000004635  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II)
[E] Gallus gallusCHICK01891  Ensembl ENSGALP00000008657   -
[E] Taeniopygia guttataTAEGU10961  Ensembl ENSTGUP00000006976   -
[E] Anolis carolinensisANOCA13256  Ensembl ENSACAP00000006080  Hydroxyacylglutathione hydrolase (EC 3.1.2.6)(Glyoxalase II)(Glx II) [Source:UniProtKB/Swiss- Prot;Acc:Q16775]
[E] Xenopus tropicalisXENTR07608  Ensembl ENSXETP00000015653  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (GLX II).
[E] Oryzias latipesORYLA17047  Ensembl ENSORLP00000011553   -
[E] Gasterosteus aculeatusGASAC11007  Ensembl ENSGACP00000015711   -
[E] Takifugu rubripesFUGRU07050  Ensembl ENSTRUP00000014493  Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II)
[E] Tetraodon nigroviridisTETNG13997  Ensembl ENSTNIP00000021169  Hydroxyacylglutathione hydrolase (EC 3.1.2.6)(Glyoxalase II)(Glx II) [Source:UniProtKB/Swiss- Prot;Acc:Q16775]
[E] Danio rerioDANRE08776  UniProtKB/Swiss-Prot GLO2_DANRE  hydroxyacylglutathione hydrolase
[E] Ciona intestinalisCIOIN05800  Ensembl ENSCINP00000018149   -
[E] Helobdella robustaHELRO00098   155548  jgi|Helro1|155548
[E] Ixodes scapularisIXOSC12065  UniProtKB/TrEMBL B7PY82  hydroxyacylglutathione hydrolase, putative
[E] Daphnia pulexDAPPU01866   fgenesh1_pg.C_scaffold_4000479  jgi|Dappu1|96363|fgenesh1_pg.C_scaffold_4000479
[E] Drosophila melanogasterDROME07860  UniProtKB/TrEMBL Q8IPU3  CG4365-PC, isoform C
[E] Drosophila pseudoobscuraDROPS09709   EAL30517  
[E] Anopheles gambiaeANOGA11400  UniProtKB/TrEMBL Q7QFD4   -
[E] Aedes aegyptiAEDAE03999  UniProtKB/TrEMBL Q16VR2   -
[E] Pristionchus pacificusPRIPA08155   WBGene00097784  status:Partially_confirmed
[E] Caenorhabditis briggsaeCAEBR08742   CBG21025  
[E] Caenorhabditis elegansCAEEL05850  UniProtKB/TrEMBL Q9XXJ1  Y17G7B.3 is orthologous to the human gene HYDROXYACYLGLUTATHIONE HYDROLASE (HAGH. OMIM:138760), which when mutated leads to disease.
[E] Caenorhabditis remaneiCAERE25601   WBGene00054434  
[E] Nematostella vectensisNEMVE05247  UniProtKB/TrEMBL A7RKI7  jgi|Nemve1|84777|e_gw.10.112.1
[E] Plasmodium falciparumPLAF701515   PFD0311w-1  
[E] Dictyostelium discoideumDICDI08584  UniProtKB/Swiss-Prot GLO2_DICDI  
[E] Phaeosphaeria nodorumPHANO09358   SNU10284.1  hypothetical protein
[E] Magnaporthe griseaMAGGR01581  UniProtKB/TrEMBL A4RH64  Magnaporthe grisea hydroxyacylglutathione hydrolase, putative
[E] Yarrowia lipolyticaYARLI03074  UniProtKB/TrEMBL Q6CA02  similar to sp|Q05584 Saccharomyces cerevisiae YDR272w GLO2 glyoxalase II (hydroxyacylglutathione hydrolase), start by similarity
[E] Kluyveromyces lactisKLULA00703  UniProtKB/TrEMBL Q6CJT8  similar to sp|Q12320 Saccharomyces cerevisiae YOR040w GLO4 glyoxalase II (hydroxyacylglutathione hydrolase), start by similarity
[E] Lodderomyces elongisporusLODEL02387  UniProtKB/TrEMBL A5DYF9  Lodderomyces elongisporus (LELG_02396.1) hydroxyacylglutathione hydrolase (translation)
[E] Pichia stipitisPICST03517  UniProtKB/TrEMBL A3LU64  hydroxyacylglutathione hydrolase
[E] Schizosaccharomyces pombeSCHPO00711  UniProtKB/Swiss-Prot GLO21_SCHPO  hydroxyacylglutathione hydrolase (predicted); similar to S. cerevisiae GLO2
[E] Cryptococcus neoformansCRYNE01722  UniProtKB/TrEMBL Q5KIL7  go_component: mitochondrion [goid 0005739]; go_component: mitochondrial matrix [goid 0005759]; go_function: hydroxyacylglutathione hydrolase activity [goid 0004416]; go_process: carbohydrate metabolism [goid 0005975] hydroxyacylglutathione hydrolase, putative
[E] Debaryomyces hanseniiDEBHA00718  UniProtKB/TrEMBL Q6BXK7  DEHA2B02178p;similar to uniprot|Q05584 Saccharomyces cerevisiae YDR272w GLO2 cytoplasmic glyoxalase II;
[E] Candida glabrataCANGA02066  UniProtKB/TrEMBL Q6FR50  similar to uniprot|Q05584 Saccharomyces cerevisiae YDR272w GLO2 glyoxalase II;
[E] Candida albicansCANAL02766  UniProtKB/TrEMBL Q59X43  hypothetical protein;similar to glyoxylase 2;
[E] Oryza sativaORYSA08170   BAF11930.1  Hydroxyacylglutathione hydrolase cytoplasmic (EC 3.1.2.6) (Glyoxalase II) (Glx II) contains InterPro domain(s): IPR001279 similar to O24496 supported by AK103161
[E] Sorghum bicolorSORBI01585  UniProtKB/TrEMBL C5X1M7  jgi|Sorbi1|147425|estExt_fgenesh1_kg.C_chr_10409
[E] Populus trichocarpaPOPTR42843  UniProtKB/TrEMBL B9N1T0  jgi|Poptr1_1|827863|estExt_fgenesh4_pg.C_1250018 [DNA did not match protein] [DNA partly invalid]
[E] Arabidopsis thalianaARATH11993  UniProtKB/Swiss-Prot GLO2C_ARATH  hydroxyacylglutathione hydrolase, cytoplasmic / glyoxalase II (GLX2-2), identical to SP|O24496 Hydroxyacylglutathione hydrolase cytoplasmic (EC 3.1.2.6) (Glyoxalase II) (Glx II) {Arabidopsis thaliana}; go_component: cytoplasm [goid GO:0004416@[IDA]; GO:0005737@[ISS]; GO:0012505@[IEA]; GO:0019243@[TAS]] [evidence ISS]; go_function: hydroxyacylglutathione hydrolase activity [goid GO:0004416] [evidence IDA] [pmid 9065762]; go_process: methylglyoxal catabolism to D-lactate [goid GO:0019243] [evidence TAS] [pmid 9065762] GLX2-2 (GLYOXALASE 2-2); hydroxyacylglutathione hydrolase
[E] Vitis viniferaVITVI14743  UniProtKB/TrEMBL A7Q3D4  
[B] Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)NEIG101044  UniProtKB/Swiss-Prot GLO2_NEIG1  Best Blastp Hit: emb|CAB83742.1| (AL162753) putative hydroxyacylglutathione hydrolase [Neisseria meningitidis] COG0491 Zn-dependent hydrolases, including; GloB putative hydroxyacylglutathione hydrolase / glyoxylase II
[B] Neisseria meningitidis serogroup ANEIMA00396  UniProtKB/Swiss-Prot GLO2_NEIMA  Putative hydroxyacylglutathione hydrolase
[B] Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / FAM18)NEIMF01771  UniProtKB/Swiss-Prot GLO2_NEIMF  Putative hydroxyacylglutathione hydrolase