| [E] Nematostella vectensis | NEMVE02904 | A8DWT4 | jgi|Nemve1|49245|gw.18372.1.1 |
| [A] Cenarchaeum symbiosum | CENSY01973 | A0RZ62 | Hydroxymethylglutaryl-CoA reductase |
| [A] Desulfurococcus kamchatkensis (strain 1221n / DSM 18924) | DESK100716 | B8D4L5 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [A] Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) | STAMF00177 | A3DKY1 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [A] Nitrosopumilus maritimus (strain SCM1) | NITMS01556 | A9A5X8 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [A] Thermofilum pendens (strain Hrk 5) | THEPD00918 | A1RYP8 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [A] Archaeoglobus fulgidus | ARCFU01706 | HMDH_ARCFU | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [A] Methanosaeta thermophila (strain DSM 6194 / PT) | METTP00914 | A0B7Q0 | hydroxymethylglutaryl-CoA reductase, degradative KEGG: afu:AF1736 3-hydroxy-3-methylglutaryl-coenzyme A reductase TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative PFAM: hydroxymethylglutaryl-coenzyme A reductase |
| [A] Picrophilus torridus | PICTO01143 | Q6KZX4 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [A] Thermoplasma acidophilum | THEAC00400 | Q9HL34 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase related protein |
| [A] Thermoplasma volcanium | THEVO01191 | Q979G8 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [A] Uncultured methanogenic archaeon RC-I | UNCMA02347 | Q0W723 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [A] Korarchaeum cryptofilum (strain OPF8) | KORCO00556 | B1L4D7 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Rhodococcus erythropolis (strain PR4 / NBRC 100887) | RHOE403490 | C1A0S1 | Putative 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) | FLAJ101412 | A5FK21 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511) | FLAPJ02273 | A6H222 | Probable hydroxymethylglutaryl-coenzyme A reductase |
| [B] Gramella forsetii (strain KT0803) | GRAFK02899 | A0M5M5 | degradative hydroxymethylglutaryl-CoA reductase |
| [B] Chloroflexus aggregans (strain MD-66 / DSM 9485) | CHLAD01098 | B8G794 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl) | CHLSY00242 | B9LHI1 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) | CHLAA00231 | A9WC96 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Roseiflexus castenholzii (strain DSM 13941 / HLO8) | ROSCS00951 | A7NHZ6 | hydroxymethylglutaryl-CoA reductase, degradative TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative KEGG: rrs:RoseRS_0431 hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Roseiflexus sp. (strain RS-1) | ROSS100414 | A5UQF9 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) | HERA203505 | A9B538 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Oceanobacillus iheyensis | OCEIH00224 | Q8ETN4 | CDS_ID OB0224 hydroxymethylglutaryl-CoA reductase |
| [B] Listeria innocua | LISIN00820 | Q92DJ2 | similar to 3-hydroxy-3-methylglutaryl-coenzyme a reductase |
| [B] Listeria monocytogenes | LISMO00822 | C8KA66 | similar to 3-hydroxy-3-methylglutaryl-coenzyme a reductase |
| [B] Listeria monocytogenes (serotype 4b / strain F2365) | LISMF00833 | Q721Z0 | identified by match to protein family HMM PF00368; match to protein family HMM TIGR00532 hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Listeria monocytogenes serotype 4a (strain HCC23) | LISMH01774 | B8DGD6 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Listeria monocytogenes serotype 4b (strain Clip81459) | LISMC00821 | C1L196 | Putative 3-hydroxy-3-methylglutaryl-coenzyme a reductase |
| [B] Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334) | LISW600819 | A0AGV5 | MvaA protein |
| [B] Staphylococcus aureus (strain COL) | STAAC02493 | Q5HD05 | identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532 hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Staphylococcus aureus (strain JH1) | STAA202552 | A6U4S6 | hydroxymethylglutaryl-CoA reductase, degradative TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative KEGG: sav:SAV2545 hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus aureus (strain JH9) | STAA902508 | A5IVX2 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Staphylococcus aureus (strain MRSA252) | STAAR02550 | Q6GDQ3 | Previously sequenced as Staphylococcus aureus 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase MvaA TR:Q9FD86 (EMBL:AF290086) (425 aa) fasta scores: E(): 1.2e-148, 97.64% id in 425 aa. Similar to Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-coenzyme A reductase MvaA SW:MVAA_PSEMV (P13702) (428 aa) fasta scores: E(): 3.2e-51, 40.41% id in 433 aa 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Staphylococcus aureus (strain MSSA476) | STAAS02450 | Q6G6C9 | Ortholog of S. aureus MRSA252 (BX571856) SAR2625 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Staphylococcus aureus (strain MW2) | STAAW02464 | Q8NUR9 | hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus aureus (strain Mu3 / ATCC 700698) | STAA102508 | A7X6Q3 | Hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus aureus (strain Mu50 / ATCC 700699) | STAAM02522 | Q7A2L0 | hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus aureus (strain N315) | STAAN02391 | Q7A3F7 | hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus aureus (strain NCTC 8325) | STAA802702 | Q2FV77 | hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Staphylococcus aureus (strain Newman) | STAAE02401 | A6QK35 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Staphylococcus aureus (strain USA300 / TCH1516) | STAAT02478 | A8Z3E5 | hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus aureus (strain USA300) | STAA302391 | Q2FDW1 | hydroxymethylglutaryl-CoA reductase identified by match to protein family HMM TIGR00532 |
| [B] Staphylococcus aureus (strain bovine RF122) | STAAB02405 | Q2YWB5 | hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus epidermidis (strain ATCC 12228) | STAES02068 | Q8CN07 | Hydroxymethylglutaryl-CoA reductase |
| [B] Staphylococcus epidermidis (strain ATCC 35984 / RP62A) | STAEQ02052 | Q5HL66 | identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532 hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Staphylococcus haemolyticus (strain JCSC1435) | STAHJ00502 | Q4L955 | HMG-CoA reductase |
| [B] Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) | STAS100326 | Q4A0D4 | similar to gi|9937370|gb|AAG02429.1| [Staphylococcus haemolyticus], percent identity 80 in 425 aa, BLASTP E(): 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Lactobacillus acidophilus | LACAC00597 | C2HN69 | HmdH COG1257 Hydroxymethylglutaryl-CoA reductase hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus brevis (strain ATCC 367 / JCM 1170) | LACBA00424 | Q03T64 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus casei (strain ATCC 334) | LACC301644 | Q037R5 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus casei (strain BL23) | LACCB01915 | B3W8R3 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081) | LACDA00849 | Q1GAH6 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365) | LACDB00713 | Q04AW1 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus fermentum (strain IFO 3956 / LMG 18251) | LACF300179 | B2GFC8 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) | LACGA01257 | Q041Y7 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus helveticus (strain DPC 4571) | LACH400510 | A8YU75 | Hydroxymethylglutaryl-coA reductase |
| [B] Lactobacillus johnsonii | LACJO01392 | Q74IG0 | hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus plantarum | LACPL00377 | Q88ZA2 | hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus reuteri (strain DSM 20016) | LACRD00194 | A5VI02 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Lactobacillus reuteri (strain JCM 1112) | LACRJ00190 | B2G5I0 | hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus sakei subsp. sakei (strain 23K) | LACSS01468 | Q38VJ6 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactobacillus salivarius subsp. salivarius (strain UCC118) | LACS100216 | Q1WV78 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase / 3-hydroxy-3-methylglutaryl-coenzyme Auctase COG1257 [I] Hydroxymethylglutaryl-CoA reductase |
| [B] Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) | PEDPA00244 | Q03HG7 | Hydroxymethylglutaryl-CoA reductase |
| [B] Leuconostoc citreum (strain KM20) | LEUCK00234 | B1MX19 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523) | LEUMM00287 | Q03ZB3 | Hydroxymethylglutaryl-CoA reductase |
| [B] Oenococcus oeni (strain BAA-331 / PSU-1) | OENOB01624 | Q04D34 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactococcus lactis subsp. cremoris (strain MG1363) | LACLM00891 | A2RJS0 | MvaA protein |
| [B] Lactococcus lactis subsp. cremoris (strain SK11) | LACLS01469 | Q02Y11 | Hydroxymethylglutaryl-CoA reductase |
| [B] Lactococcus lactis subsp. lactis | LACLA01536 | Q9CFB1 | Hydroxymethylglutaryl-CoA reductase |
| [B] Streptococcus agalactiae (serotype III) | STRA301288 | Q8E4L4 | similar to 3-hydroxy-3-methylglutaryl-coenzyme A reductase Unknown |
| [B] Streptococcus agalactiae (serotype V) | STRA501269 | Q8DZ05 | identified by match to PFAM protein family HMM PF00368 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Streptococcus agalactiae serotype Ia | STRA101216 | Q3K0J5 | identified by match to protein family HMM PF00368; match to protein family HMM TIGR00532 hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Streptococcus equi subsp. equi (strain 4047) | STRE401002 | C0M9R2 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Streptococcus equi subsp. zooepidemicus (strain H70) | STRS700878 | C0MEL0 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase Ortholog of S. equi 4047 (FM204883) SEQ1108 |
| [B] Streptococcus equi subsp. zooepidemicus (strain MGCS10565) | STREM01029 | B4U365 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase HmgA |
| [B] Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288) | STRGC00240 | A8AUV2 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Streptococcus mutans | STRMU00849 | Q8DUI6 | Best Blastp Hit: gb|AAG02449.1|AF290096_2 (AF290096) HMG-CoA reductase [Streptococcus pyogenes] putative hydroxymethylglutaryl-CoA reductase |
| [B] Streptococcus pneumoniae | STRPN01590 | Q97PB4 | identified by match to PFAM protein family HMM PF00368 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Streptococcus pneumoniae (strain ATCC BAA-255 / R6) | STRR601560 | Q8DNS5 | 3-hydroxy-3-methylglutaryl-coenzyme a reductase |
| [B] Streptococcus pneumoniae (strain CGSP14) | STRPS01682 | B2IS75 | 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Streptococcus pneumoniae (strain Hungary19A-6) | STRPI01663 | B1I782 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Streptococcus pneumoniae (strain JJA) | STRZJ01539 | C1CFU7 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Streptococcus pneumoniae serotype 19F (strain G54) | STRP401602 | B5E772 | 3-hydroxy-3-methylglutaryl-coenzyme a reductase |
| [B] Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) | STRP201454 | Q04J48 | hydroxymethylglutaryl-CoA reductase, degradative equivalent gene in S.pneumoniae TIGR4 = SP1726; equivalent gene in S.pneumoniae R6 = spr1570; identified by match to protein family HMM TIGR00532 |
| [B] Streptococcus pyogenes (serotype M18) | STRP800745 | Q8P1D3 | best blastp match gb|AAG02449.1|AF290096_2 (AF290096) HMG-CoA reductase [Streptococcus pyogenes] HMG-CoA reductase |
| [B] Streptococcus pyogenes (serotype M3) | STRP300598 | Q7CF80 | best blastp hit: gb|AAG02449.1|AF290096_2 (AF290096) HMG-CoA reductase [Streptococcus pyogenes] putative 3-hydroxy-3-methylglutaryl-coenzyme A |
| [B] Streptococcus pyogenes (serotype M6) | STRP600699 | Q5XCM5 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Streptococcus pyogenes serotype M1 | STRP101200 | Q9A094 | Putative 3-hydroxy-3-methylglutaryl-coenzyme A |
| [B] Streptococcus pyogenes serotype M12 (strain MGAS2096) | STRPB00746 | Q1JC98 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase / 3-hydroxy-3-methylglutaryl-coenzyme A reductase bifunctional |
| [B] Streptococcus pyogenes serotype M12 (strain MGAS9429) | STRPC00734 | Q1JM82 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Streptococcus pyogenes serotype M2 (strain MGAS10270) | STRPD00727 | Q1JHC7 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase / 3-hydroxy-3-methylglutaryl-coenzyme A reductase bifunctional |
| [B] Streptococcus pyogenes serotype M28 | STRPM00660 | Q48U27 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Streptococcus pyogenes serotype M4 (strain MGAS10750) | STRPF00766 | Q1J746 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase / 3-hydroxy-3-methylglutaryl-coenzyme A reductase bifunctional |
| [B] Streptococcus pyogenes serotype M49 (strain NZ131) | STRPZ00649 | B5XKZ8 | Hydroxymethylglutaryl-CoA reductase |
| [B] Streptococcus pyogenes serotype M5 (strain Manfredo) | STRPG01094 | A2RF22 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Streptococcus sanguinis (strain SK36) | STRSV00322 | A3CKT9 | Hydroxymethylglutaryl-CoA reductase, putative |
| [B] Streptococcus suis (strain 05ZYH33) | STRSY01626 | A4VWW9 | Hydroxymethylglutaryl-CoA reductase |
| [B] Streptococcus suis (strain 98HAH33) | STRS201640 | A4W372 | Hydroxymethylglutaryl-CoA reductase |
| [B] Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) | STRT200549 | Q5M5B5 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) | STRTD00484 | Q03LN5 | Hydroxymethylglutaryl-CoA reductase |
| [B] Streptococcus thermophilus (strain CNRZ 1066) | STRT100549 | Q5M0S9 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Silicibacter pomeroyi | SILPO03954 | Q5LL64 | identified by similarity to SP:P13702; match to protein family HMM PF00368; match to protein family HMM TIGR00532 hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) | BORPD03272 | A9HWZ9 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Burkholderia cenocepacia (strain HI2424) | BURCH03471 | A0AXW8 | hydroxymethylglutaryl-CoA reductase, degradative TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative KEGG: sil:SPOA0163 hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Burkholderia cenocepacia (strain MC0-3) | BURCC03975 | B1K6G7 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Burkholderia cepacia (strain J2315 / LMG 16656) | BURCJ03944 | B4EKH5 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Delftia acidovorans (strain DSM 14801 / SPH-1) | DELAS00286 | A9BQX8 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Bdellovibrio bacteriovorus | BDEBA01480 | Q6MMK1 | unnamed protein product; InterPro: Hydroxymethylglutaryl-CoA reductase degradative hypothetical protein |
| [B] Myxococcus xanthus (strain DK 1622) | MYXXD04818 | Q1D2E8 | hydroxymethylglutaryl-CoA reductase identified by match to protein family HMM PF00368; match to protein family HMM TIGR00532 |
| [B] Sorangium cellulosum (strain So ce56) | SORC503001 | A9GFK9 | Putative 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Legionella pneumophila (strain Corby) | LEGPC01486 | A5IDN7 | Hydroxymethylglutaryl CoA reductase |
| [B] Legionella pneumophila (strain Lens) | LEGPL02023 | Q5WUY7 | Similar to 3-hydroxy-3-methylglutaryl-coenzyme A reductase hypothetical protein |
| [B] Legionella pneumophila (strain Paris) | LEGPA02026 | Q5X3J9 | Similar to 3-hydroxy-3-methylglutaryl-coenzyme A reductase hypothetical protein |
| [B] Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152) | LEGPH01993 | Q5ZTV6 | conserved gene hydroxymethylglutaryl CoA reductase |
| [B] Pseudomonas putida (strain F1 / ATCC 700007) | PSEP103019 | A5W4Z1 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Borrelia afzelii (strain PKo) | BORAP00693 | Q0SMG8 | 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Borrelia burgdorferi | BORBU00685 | HMDH_BORBU | similar to SP:P13702 GB:M29727 GB:M31807 PID:151259 percent identity: 33.69; identified by sequence similarity; putative 3-hydroxy-3-methylglutaryl-CoA reductase (mvaA) |
| [B] Borrelia burgdorferi (strain ZS7) | BORBZ00651 | B7J2P0 | Hydroxymethylglutaryl-CoA reductase, degradative |
| [B] Borrelia duttonii (strain Ly) | BORDL00657 | B5RMN1 | 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Borrelia garinii | BORGA00677 | Q660I5 | 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Borrelia hermsii (strain DAH) | BORHD00658 | B2S128 | Putative uncharacterized protein |
| [B] Borrelia recurrentis (strain A1) | BORRA00645 | B5RQ27 | 3-hydroxy-3-methylglutaryl-CoA reductase |
| [B] Borrelia turicatae (strain 91E135) | BORT900657 | A1R0B0 | Probable 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| [B] Acholeplasma laidlawii (strain PG-8A) | ACHLI00205 | A9NER9 | 3-hydroxy-3-methylglutaryl-CoA reductase |