List of all proteins in the group
Allows comparison of IDs and descriptions
of all proteins in the OMA Group.
Display an MSA of all sequences in the group.
The MSA is created using the Mafft program.
The jalview applet allows for numerous
display and export options.
Display closely related groups
The close groups are made of the set of all
groups that are linked by at least one pair
of orthologs.
Note that not all pairs of proteins coming
from close groups are orthologous. If that
were the case, the two groups would have
been merged.
Display phyletic profile
The "Phyletic profile" displays OMA groups
that have similar patterns of presence/absence
across species. This can be useful to detect
proteins that have complementary function
(e.g. member of the same metabolic pathway).
Compare GO annotations
This function displays a table of all
Gene Ontology (GO) annotations on
proteins of the OMA group. This
allows to compare the annotations
and serves as an additional description
of this OMA group.
OMA fingerprint
The fingerprint is a subsequence that is specific to a
certain group in the current OMA release
Since the group number is specific to a release, this
is the best way to track a group across releases.
OMA

Keyword Protein Sequence Group Entry

OMA Group 212643

e lyase
This group has 91 members: 47 [E]ukaryota 44 [B]acteria
Fingerprint: MTLLQKF

Protein List | Alignment | Close Groups | Phyletic Profile | Ontology Download: download fasta, download darwin

[E] Homo sapiensHUMAN07191  UniProtKB/Swiss-Prot LGUL_HUMAN   -
[E] Pan troglodytesPANTR22301  Ensembl ENSPTRP00000030963   -
[E] Pongo pygmaeus abeliiPONAB08411  Ensembl ENSPPYP00000018532  Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D- lactoylglutathione methylglyoxal lyase).
[E] Macaca mulattaMACMU05965  Ensembl ENSMMUP00000002187   -
[E] Tarsius syrichtaTARSY09372  Ensembl ENSTSYP00000006902  Lactoylglutathione lyase (EC 4.4.1.5)(Methylglyoxalase)(Aldoketomutase)(Glyoxalase I)(Glx I)(Ketone-aldehyde mutase)(S-D-lactoylglutathione methylglyoxal lyase) [Source:UniProtKB/Swiss- Prot;Acc:Q04760]
[E] Microcebus murinusMICMU12826  Ensembl ENSMICP00000015709   -
[E] Cavia porcellusCAVPO00612  Ensembl ENSCPOP00000009023  Lactoylglutathione lyase (EC 4.4.1.5)(Methylglyoxalase)(Aldoketomutase)(Glyoxalase I)(Glx I)(Ketone-aldehyde mutase)(S-D-lactoylglutathione methylglyoxal lyase) [Source:UniProtKB/Swiss- Prot;Acc:Q04760]
[E] Dipodomys ordiiDIPOR09210  Ensembl ENSDORP00000005960  
[E] Mus musculusMOUSE15173  UniProtKB/Swiss-Prot LGUL_MOUSE  glyoxalase 1
[E] Rattus norvegicusRATNO12217  UniProtKB/Swiss-Prot LGUL_RAT  Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D- lactoylglutathione methylglyoxal lyase). [Source:UniProtKB/Swiss- Prot;Acc:Q6P7Q4]
[E] Loxodonta africanaLOXAF07569  Ensembl ENSLAFP00000008705   -
[E] Echinops telfairiECHTE11334  Ensembl ENSETEP00000007791   -
[E] Canis familiarisCANFA01589  Ensembl ENSCAFP00000002151   -
[E] Tursiops truncatusTURTR03969  Ensembl ENSTTRP00000004377   -
[E] Bos taurusBOVIN11957  Ensembl ENSBTAP00000016884  MGC139859 protein
[E] Lama guanicoe pacosLAMPA05752  Ensembl ENSVPAP00000003588  Lactoylglutathione lyase (EC 4.4.1.5)(Methylglyoxalase)(Aldoketomutase)(Glyoxalase I)(Glx I)(Ketone-aldehyde mutase)(S-D-lactoylglutathione methylglyoxal lyase) [Source:UniProtKB/Swiss- Prot;Acc:Q04760]
[E] Pteropus vampyrusPTEVA11627  Ensembl ENSPVAP00000013029   -
[E] Erinaceus europaeusERIEU08649  Ensembl ENSEEUP00000004189   -
[E] Sorex araneusSORAR06293  Ensembl ENSSARP00000009658   -
[E] Equus caballusHORSE07627  Ensembl ENSECAP00000017243  Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D- lactoylglutathione methylglyoxal lyase).
[E] Dasypus novemcinctusDASNO04346  Ensembl ENSDNOP00000015197   -
[E] Choloepus hoffmanniCHOHO05003  Ensembl ENSCHOP00000010587  
[E] Monodelphis domesticaMONDO07090  Ensembl ENSMODP00000016559  Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D- lactoylglutathione methylglyoxal lyase).
[E] Ornithorhynchus anatinusORNAN05469  Ensembl ENSOANP00000027666  Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D- lactoylglutathione methylglyoxal lyase)
[E] Gallus gallusCHICK09842  Ensembl ENSGALP00000016450   -
[E] Taeniopygia guttataTAEGU15368  Ensembl ENSTGUP00000008043   -
[E] Anolis carolinensisANOCA08210  Ensembl ENSACAP00000014057  Lactoylglutathione lyase (EC 4.4.1.5)(Methylglyoxalase)(Aldoketomutase)(Glyoxalase I)(Glx I)(Ketone-aldehyde mutase)(S-D-lactoylglutathione methylglyoxal lyase) [Source:UniProtKB/Swiss- Prot;Acc:Q04760]
[E] Xenopus tropicalisXENTR15944  Ensembl ENSXETP00000023525  Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D- lactoylglutathione methylglyoxal lyase).
[E] Oryzias latipesORYLA13156  Ensembl ENSORLP00000018608   -
[E] Gasterosteus aculeatusGASAC01907  Ensembl ENSGACP00000019581   -
[E] Takifugu rubripesFUGRU12648  Ensembl ENSTRUP00000018316  Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D- lactoylglutathione methylglyoxal lyase)
[E] Tetraodon nigroviridisTETNG07946  Ensembl ENSTNIP00000014859  Lactoylglutathione lyase (EC 4.4.1.5)(Methylglyoxalase)(Aldoketomutase)(Glyoxalase I)(Glx I)(Ketone-aldehyde mutase)(S-D-lactoylglutathione methylglyoxal lyase) [Source:UniProtKB/Swiss- Prot;Acc:Q04760]
[E] Danio rerioDANRE02591  UniProtKB/TrEMBL Q6P696  glyoxalase 1
[E] Ciona intestinalisCIOIN00663  Ensembl ENSCINP00000012806   -
[E] Lottia giganteaLOTGI17260   191038  jgi|Lotgi1|191038|estExt_Genewise1.C_sca_370066
[E] Daphnia pulexDAPPU21256   estExt_fgenesh1_kg.C_2300001  jgi|Dappu1|231858|estExt_fgenesh1_kg.C_2300001
[E] Drosophila melanogasterDROME02732  UniProtKB/TrEMBL A1Z6X6  CG1707-PA
[E] Anopheles gambiaeANOGA08112  UniProtKB/TrEMBL Q7PZT5   -
[E] Aedes aegyptiAEDAE09467  UniProtKB/TrEMBL Q16GF9   -
[E] Nematostella vectensisNEMVE22713  UniProtKB/TrEMBL A7S7N5  jgi|Nemve1|237677|estExt_fgenesh1_kg.C_14550001
[E] Phaeosphaeria nodorumPHANO12415  UniProtKB/TrEMBL Q0U8E8  hypothetical protein
[E] Laccaria bicolorLACBI01212   estExt_Genewise1_human.C_50676  jgi|Lacbi1|172709|estExt_Genewise1_human.C_50676
[E] Cryptococcus neoformansCRYNE04389  UniProtKB/TrEMBL Q5KB67  go_function: lactoylglutathione lyase activity [goid 0004462]; go_process: glutathione metabolism [goid 0006749] lactoylglutathione lyase, putative
[E] Oryza sativaORYSA13215   BAF17027.1  Glyoxalase I (EC 4.4.1.5) contains InterPro domain(s): IPR004360, IPR004361 has GO asignment(s): GO:0004462, GO:0005975 similar to Q9ZS21 supported by AK070232
[E] Sorghum bicolorSORBI01202   145192  jgi|Sorbi1|145192|estExt_fgenesh1_pm.C_chr_60049
[E] Populus trichocarpaPOPTR31043  UniProtKB/TrEMBL A9P8N6  jgi|Poptr1_1|749645|fgenesh4_kg.C_LG_IX000057 [DNA did not match protein] [DNA partly invalid]
[E] Vitis viniferaVITVI01355  UniProtKB/TrEMBL A7PQS5  
[B] Phenylobacterium zucineum (strain HLK1)PHEZH00382  UniProtKB/TrEMBL B4RDU7  Lactoylglutathione lyase
[B] Verminephrobacter eiseniae (strain EF01-2)VEREI02626  UniProtKB/TrEMBL A1WLD8  Lactoylglutathione lyase
[B] Methylibium petroleiphilum (strain PM1)METPP03561  UniProtKB/TrEMBL A2SLY1  Lactoylglutathione lyase
[B] Bdellovibrio bacteriovorusBDEBA02607  UniProtKB/TrEMBL Q6MJD2  InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily hypothetical protein lactoylglutathione lyase
[B] Alteromonas macleodii (strain DSM 17117 / Deep ecotype)ALTMD00918  UniProtKB/TrEMBL B4RT20  Lactoylglutathione lyase
[B] Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)MARAV02883  UniProtKB/TrEMBL A1U510  lactoylglutathione lyase KEGG: abo:ABO_0095 lactoylglutathione lyase TIGRFAM: lactoylglutathione lyase PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
[B] Idiomarina loihiensisIDILO02601  UniProtKB/TrEMBL Q5QZJ8  Lactoylglutathione lyase
[B] Pseudoalteromonas atlantica (strain T6c / BAA-1087)PSEA602607  UniProtKB/TrEMBL Q15SJ0  Lactoylglutathione lyase
[B] Pseudoalteromonas haloplanktis (strain TAC 125)PSEHT01558  UniProtKB/TrEMBL Q3IGQ9  Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7959071; Product type e : enzyme Lactoylglutathione lyase (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D-lactoylglutathione methylglyoxal lyase)
[B] Halorhodospira halophila (strain DSM 244 / SL1)HALHL00885  UniProtKB/TrEMBL A1WVH0  Lactoylglutathione lyase
[B] Thioalkalivibrio sp. (strain HL-EbGR7)THISH00015  UniProtKB/TrEMBL B8GST5  Lactoylglutathione lyase
[B] Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)ALCBS00095  UniProtKB/TrEMBL Q0VTK0  Lactoylglutathione lyase
[B] Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)CHRSD00216  UniProtKB/TrEMBL Q1R127  Glyoxalase I
[B] Psychrobacter arcticus (strain DSM 17307 / 273-4)PSYA200216  UniProtKB/TrEMBL Q4FV67  Probable lactoylglutathione lyase
[B] Psychrobacter cryohalolentis (strain K5)PSYCK00241  UniProtKB/TrEMBL Q1QE78  Glyoxalase I
[B] Pseudomonas aeruginosaPSEAE05098  UniProtKB/Swiss-Prot LGUL_PSEAE  Lactoylglutathione lyase
[B] Pseudomonas aeruginosa (strain LESB58)PSEA805473  UniProtKB/TrEMBL B7V3K4  Lactoylglutathione lyase
[B] Pseudomonas aeruginosa (strain PA7)PSEA705727  UniProtKB/TrEMBL A6VDM8  Lactoylglutathione lyase
[B] Pseudomonas aeruginosa (strain UCBPP-PA14)PSEAB05420  UniProtKB/TrEMBL Q02EQ5  lactoylglutathione lyase
[B] Pseudomonas entomophila (strain L48)PSEE402969  UniProtKB/TrEMBL Q1I8Q7  lactoylglutathione lyase Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7959071; Product type e : enzyme
[B] Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)PSEF503345  UniProtKB/TrEMBL Q4KB85  identified by match to protein family HMM PF00903; match to protein family HMM TIGR00068 lactoylglutathione lyase
[B] Pseudomonas fluorescens (strain PfO-1)PSEPF02913  UniProtKB/TrEMBL Q3KC41  Glyoxalase I
[B] Pseudomonas mendocina (strain ymp)PSEMY04148  UniProtKB/TrEMBL A4Y038  Lactoylglutathione lyase
[B] Pseudomonas putida (strain F1 / ATCC 700007)PSEP101956  UniProtKB/TrEMBL A5W1X7  Lactoylglutathione lyase
[B] Pseudomonas putida (strain GB-1)PSEPG02115  UniProtKB/TrEMBL B0KMI2  lactoylglutathione lyase unknown EC_number=4.4.1.5 KEGG: pen:PSEEN3212 lactoylglutathione lyase TIGRFAM: lactoylglutathione lyase PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase
[B] Pseudomonas putida (strain KT2440)PSEPK03707  UniProtKB/TrEMBL Q88GF8  similar to GB:Z14955, GB:Z14954, GB:Z29574, GB:Z29575, SP:Q02223, PID:1930146, PID:29408, PID:33807, PID:471245, and PID:499189; identified by sequence similarity; putative lactoylglutathione lyase
[B] Pseudomonas putida (strain W619)PSEPW02094  UniProtKB/TrEMBL B1J720  Lactoylglutathione lyase
[B] Pseudomonas syringae (pv. tomato)PSESM02950  UniProtKB/TrEMBL Q880P8  identified by match to PFAM protein family HMM PF00903 lactoylglutathione lyase
[B] Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6)PSE1402113  UniProtKB/TrEMBL Q48JF2  identified by match to protein family HMM PF00903; match to protein family HMM TIGR00068 lactoylglutathione lyase
[B] Pseudomonas syringae pv. syringae (strain B728a)PSEU202956  UniProtKB/TrEMBL Q4ZS65  Glyoxalase I
[B] Stenotrophomonas maltophilia (strain K279a)STRMK03840  UniProtKB/TrEMBL B2FHX3  Putative lactoylglutathione lyase
[B] Stenotrophomonas maltophilia (strain R551-3)STRM503477  UniProtKB/TrEMBL B4SJQ4  Lactoylglutathione lyase
[B] Xanthomonas axonopodis (pv. citri)XANAC03533  UniProtKB/TrEMBL Q8PGI4  identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark lactoylglutathione lyase
[B] Xanthomonas campestris pv. campestrisXANCP00564  UniProtKB/TrEMBL Q8PCX6  Lactoylglutathione lyase
[B] Xanthomonas campestris pv. campestris (strain 8004)XANC803554  UniProtKB/TrEMBL Q4UQH4  lactoylglutathione lyase
[B] Xanthomonas campestris pv. campestris (strain B100)XANCB03760  UniProtKB/TrEMBL B0RVQ2  Lactoylglutathione lyase
[B] Xanthomonas campestris pv. vesicatoria (strain 85-10)XANC503661  UniProtKB/TrEMBL Q3BP33  Lactoylglutathione lyase
[B] Xanthomonas oryzae (pv. oryzae)XANOR00665  UniProtKB/TrEMBL Q5H4W2  identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark lactoylglutathione lyase
[B] Xanthomonas oryzae pv. oryzae (strain MAFF 311018)XANOM00623  UniProtKB/TrEMBL Q2P7N8  lactoylglutathione lyase identified by sequence similarity; putative; ORF located using Blastx/Glimmer/GeneHacker
[B] Xanthomonas oryzae pv. oryzae (strain PXO99A)XANOP04004  UniProtKB/TrEMBL B2SQ90  Lactoylglutathione lyase
[B] Xylella fastidiosaXYLFA01392  UniProtKB/TrEMBL Q9PDI0  similar to SP|P16635 (percent identity: 63 %/query alignment coverage: 97.7 %/subject alignment coverage: 98.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder lactoylglutathione lyase
[B] Xylella fastidiosa (strain M12)XYLFM00648  UniProtKB/TrEMBL B0U6M3  Lactoylglutathione lyase
[B] Xylella fastidiosa (strain M23)XYLF200627  UniProtKB/TrEMBL B2I9L0  Lactoylglutathione lyase
[B] Xylella fastidiosa (strain Temecula1 / ATCC 700964)XYLFT00584  UniProtKB/TrEMBL Q87DQ2  Lactoylglutathione lyase