Entry MYCA902080 (PYRD_MYCA9)

BMycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)


General information

Description
Probable dihydroorotate dehydrogenase
Organism
MYCA9 - Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Locus
Chromosome: complement(2105078..2106139)
InterPro
IPR001295

IDs and Cross-references

UniProtKB/Swiss-Prot
UniProtKB/Swiss-Prot PYRD_MYCA9 (Acc.: B1MPD4)
NCBI
ncbi logo CAM62185.1
Other IDs
MAB_2104c

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
catalytic activity (GO:0003824) IEA: GO_REF:002
dihydroorotate dehydrogenase activity (GO:0004152) IEA: GO_REF:002, GO_REF:003
oxidoreductase activity (GO:0016491) IEA: GO_REF:037
oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627) IEA: GO_REF:002
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor (GO:0016628) IEA: OMA_Fun:001

Cellular component
GO termEvidence and reference
cytoplasm (GO:0005737) IEA: GO_REF:002
cytosol (GO:0005829) IEA: OMA_Fun:001
plasma membrane (GO:0005886) IEA: GO_REF:037, GO_REF:039
membrane (GO:0016020) IEA: GO_REF:002, GO_REF:037
integral component of membrane (GO:0016021) IEA: OMA_Fun:001

Biological process
GO termEvidence and reference
'de novo' pyrimidine nucleobase biosynthetic process (GO:0006207) IEA: GO_REF:002
pyrimidine nucleotide biosynthetic process (GO:0006221) IEA: GO_REF:037
UMP biosynthetic process (GO:0006222) IEA: GO_REF:002
'de novo' UMP biosynthetic process (GO:0044205) IEA: GO_REF:041
oxidation-reduction process (GO:0055114) IEA: GO_REF:002, GO_REF:037

Protein Sequence

MLYQILLRLF FLVSPERVHT LVFAALRAIA AFTPTRWLLN RLCAPTDPIL GTEVFGVHFP    60
APLGLAAGFD KDGEGLKVWG PLGFGYAEVG TVTAIAQPGN PKPRLFRLPA DRGLLNRMGF   120
NNHGAAALAP RLATRTSTVP IGANIGKSKI VEPAFASSDY RVSARQVGPA ADFLVVNVSS   180
PNTPGLRDLQ AIGELRKILS AVLEETTAPV LVKIAPDLSD ADIDEIADLA VELGLAGIVA   240
TNTTISRAAL KTTGVEDLGA GGVSGPPVAA RSLEVLRRLY RRVGDRLVLI SVGGIEDADD   300
AWARIIAGAS LLQGYTGFIY RGGFYAKRIH DGIAQRLRAG GFASLQDAVG SAT          353