Entry STRAW05395 (Q82CF3)

BStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)


General information

Description
Aspartate-semialdehyde dehydrogenase
Organism
STRAW - Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Locus
Chromosome: complement(6543990..6545006)
InterPro
IPR000319
Protein Structures
pmp logo Protein Model Portal: Q82CF3

IDs and Cross-references

UniProtKB/TrEMBL
UniProtKB/TrEMBL Q82CF3
NCBI
ncbi logo BAC73109.1
Other IDs
SAV5397

Domain Architecture

Gene Ontology

Molecular function
GO termEvidence and reference
N-acetyl-gamma-glutamyl-phosphate reductase activity (GO:0003942) IEA: GO_REF:002
aspartate-semialdehyde dehydrogenase activity (GO:0004073) IEA: GO_REF:002, GO_REF:003, GO_REF:020
oxidoreductase activity (GO:0016491) IEA: GO_REF:038
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620) IEA: GO_REF:002
protein dimerization activity (GO:0046983) IEA: GO_REF:002
NADP binding (GO:0050661) IEA: GO_REF:002, GO_REF:020
NAD binding (GO:0051287) IEA: GO_REF:002

Cellular component
GO termEvidence and reference
cytoplasm (GO:0005737) IEA: GO_REF:002

Biological process
GO termEvidence and reference
cellular amino acid metabolic process (GO:0006520) IEA: GO_REF:002
cellular amino acid biosynthetic process (GO:0008652) IEA: GO_REF:002, GO_REF:038
lysine biosynthetic process (GO:0009085) IEA: GO_REF:038
methionine biosynthetic process (GO:0009086) IEA: GO_REF:002, GO_REF:038
threonine biosynthetic process (GO:0009088) IEA: GO_REF:002, GO_REF:020, GO_REF:038, GO_REF:041
lysine biosynthetic process via diaminopimelate (GO:0009089) IEA: GO_REF:002, GO_REF:020, GO_REF:041
isoleucine biosynthetic process (GO:0009097) IEA: GO_REF:002
diaminopimelate biosynthetic process (GO:0019877) IEA: GO_REF:020, GO_REF:038
oxidation-reduction process (GO:0055114) IEA: GO_REF:002, GO_REF:038
'de novo' L-methionine biosynthetic process (GO:0071266) IEA: GO_REF:020

Protein Sequence

MRVGIVGATG QVGTVMRRIL VERDFPVTEL RLFASARSAG SVVDGVTVED ASTADYTGLD    60
IVLFSAGGAT SRALCEKVAA QGAVVIDNSS AWRKDPAVPL VVAEVNPHAI ADRPKGIIAN   120
PNCTTMAAMP VLKPLHEEAG LEALIVATYQ AVSGSGVAGV AELHGQAQKV IADADKLTHD   180
GEAVDYPEPQ VYQRPIAFNV VPLAGSLVDD GLHETDEEQK LRNESRKILE IPALKVSGTC   240
VRVPVFSGHS LQVNARFARP LSVERATELL GGAPGVALSE IPTPLEAAGK DPSFVGRIRA   300
DETVDNGLAL FISNDNLRKG AALNAVQIAE LVAAELKG                           338